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Protein

NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic

Gene

ndhF

Organism
Lactuca sativa (Garden lettuce)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.UniRule annotation

Catalytic activityi

NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
Biological processTransportUniRule annotation
LigandNADUniRule annotationSAAS annotation, NADPUniRule annotationSAAS annotation, PlastoquinoneUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H-quinone oxidoreductase subunit 5, chloroplasticUniRule annotation (EC:1.6.5.-UniRule annotation)
Alternative name(s):
NADH-plastoquinone oxidoreductase subunit 5UniRule annotation
Gene namesi
Name:ndhFUniRule annotationImported
Encoded oniPlastid; ChloroplastImported
OrganismiLactuca sativa (Garden lettuce)Imported
Taxonomic identifieri4236 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeCichorioideaeCichorieaeLactucinaeLactuca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei50 – 74HelicalUniRule annotationAdd BLAST25
Transmembranei86 – 104HelicalUniRule annotationAdd BLAST19
Transmembranei110 – 131HelicalUniRule annotationAdd BLAST22
Transmembranei152 – 168HelicalUniRule annotationAdd BLAST17
Transmembranei188 – 207HelicalUniRule annotationAdd BLAST20
Transmembranei228 – 252HelicalUniRule annotationAdd BLAST25
Transmembranei258 – 276HelicalUniRule annotationAdd BLAST19
Transmembranei292 – 313HelicalUniRule annotationAdd BLAST22
Transmembranei319 – 340HelicalUniRule annotationAdd BLAST22
Transmembranei361 – 382HelicalUniRule annotationAdd BLAST22
Transmembranei394 – 416HelicalUniRule annotationAdd BLAST23
Transmembranei514 – 535HelicalUniRule annotationAdd BLAST22
Transmembranei570 – 588HelicalUniRule annotationAdd BLAST19

Keywords - Cellular componenti

ChloroplastUniRule annotationImported, Membrane, Plastid, ThylakoidUniRule annotation

PTM / Processingi

Keywords - PTMi

QuinoneUniRule annotation

Interactioni

Subunit structurei

NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 94Proton_antipo_NInterPro annotationAdd BLAST58
Domaini106 – 407Proton_antipo_MInterPro annotationAdd BLAST302
Domaini413 – 654Proton_antipo_CInterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the complex I subunit 5 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR002128. NADH_UbQ_OxRdtase_chlpt_su5_C.
IPR003945. NADHpl_OxRdtase_5.
IPR018393. NADHpl_OxRdtase_5_subgr.
IPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
PfamiView protein in Pfam
PF01010. Proton_antipo_C. 1 hit.
PF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
PRINTSiPR01435. NPOXDRDTASE5.
TIGRFAMsiTIGR01974. NDH_I_L. 1 hit.

Sequencei

Sequence statusi: Fragment.

D0G846-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LRRMWSFQSV LLLSIVMIFS MNLSIQQINS SYVYQYVWSW IINNDFSLEF
60 70 80 90 100
GYLIDPLTSI MLILITTVGI MVLIYSDNYM SHDHGYLRFF AYMSFFSTSM
110 120 130 140 150
LGLVTSSNLI QIYIFWELVG ICSYLLIGFW FTRPVAAKAC QKAFVTNRVG
160 170 180 190 200
DFGLLLGILG FYWITGSFEF RDLFQIFNNL ISNNEVNFLF VTLCAILLFA
210 220 230 240 250
GAIAKSAQFP LHVWLPDAME GPTPISALIH AATMVAAGIF LVARLMPLFI
260 270 280 290 300
VIPHIMNFIS LIGIITVFLG ATLALAQKDI KRGLAYSTMS QLGYMMLALG
310 320 330 340 350
MGSYRSALFH LITHAYSKAL LFLGSGSVIH SMETLVGYCP KKSQNMVLMG
360 370 380 390 400
GLTKHLPITK NSFLLGTLSL CGIPPLACFW SKDEILNDSW LYSPIFGIIA
410 420 430 440 450
WSTAGLTAFY MCRIYLLTFE GHLNVHFQNY SGKRNTPFYS ISLWGKEGSK
460 470 480 490 500
ISNKNFSLVT LLKMKKNPRP SFFSNNKVYK IDENVRNMIQ PFLSIPHFGN
510 520 530 540 550
TKTYSYPYES DNTMLFPILI LILFTLFVGF LGIPFNQDVD ILSKWLNPSI
560 570 580 590 600
NLLHQNSNNS IDWYEFSKDA FFSVSIASFG IFIAFFLYKP VYSSFQNLEF
610 620 630 640 650
LNTFVKMGPN RIFYDKIKNS IYDWSYNRGY IDAFYGRFLT AGIRKLANFA
660
HFFDRRIIDA IPNGVGLMS
Length:669
Mass (Da):76,166
Last modified:December 15, 2009 - v1
Checksum:iFF8BE1699CF81EB1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei669Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB530948 Genomic DNA. Translation: BAI49099.1.

Similar proteinsi

Entry informationi

Entry nameiD0G846_LACSA
AccessioniPrimary (citable) accession number: D0G846
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: August 30, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation