Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D0FRY7

- D0FRY7_ERWPE

UniProt

D0FRY7 - D0FRY7_ERWPE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene

dadB

Organism
Erwinia pyrifoliae (strain Ep1/96)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei130 – 1301SubstrateUniRule annotation
Active sitei253 – 2531Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei301 – 3011Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciEPYR634499:GJIP-1682-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:dadBImported
Ordered Locus Names:EpC_16230Imported
OrganismiErwinia pyrifoliae (strain Ep1/96)Imported
Taxonomic identifieri634499 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia
ProteomesiUP000007061: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi634499.EpC_16230.

Structurei

3D structure databases

ProteinModelPortaliD0FRY7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.
OMAiPVELWGQ.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0FRY7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRPIVATIN RAALRQNLAI ARYTAGGARL WSVVKANAYG HGIDHVWQSL
60 70 80 90 100
NETDGFALLN LEEAILLRER GWKKPILLLE GFFHPDDLQI LDRYRLTTSV
110 120 130 140 150
HSNWQINALA QAKLSAPIDI YLKMNSGMNR LGFQPERVHG VWQKLRSLEN
160 170 180 190 200
VGELTLMAHF ADAESAEGVA EPLKRIEQAA EGLECPRSLA NSAATLWHPQ
210 220 230 240 250
THYDWVRPGI ILYGASPSGQ WQDIAGSGLQ PVMTLTSEVI AVQQLAAGSG
260 270 280 290 300
VGYGSRYRAN CSQRIGVVAC GYADGYPRHA PTGTPIRVDG EKTQIVGAVS
310 320 330 340 350
MDMITVDLTP CLQAGIGSQV ELWGDNVKID DVASASGTVG YELMCALAPR

VPVRVV
Length:356
Mass (Da):38,705
Last modified:November 24, 2009 - v1
Checksum:iCAAEF0626C690AED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP236842 Genomic DNA. Translation: CAX55402.1.
RefSeqiYP_002648633.1. NC_012214.1.

Genome annotation databases

EnsemblBacteriaiCAX55402; CAX55402; EpC_16230.
GeneIDi8541143.
KEGGiepy:EpC_16230.
PATRICi20421466. VBIErwPyr67807_1629.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FP236842 Genomic DNA. Translation: CAX55402.1 .
RefSeqi YP_002648633.1. NC_012214.1.

3D structure databases

ProteinModelPortali D0FRY7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 634499.EpC_16230.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAX55402 ; CAX55402 ; EpC_16230 .
GeneIDi 8541143.
KEGGi epy:EpC_16230.
PATRICi 20421466. VBIErwPyr67807_1629.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.
OMAi PVELWGQ.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci EPYR634499:GJIP-1682-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome comparison of the epiphytic bacteria Erwinia billingiae and E. tasmaniensis with the pear pathogen E. pyrifoliae."
    Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H., Knaust F., Geider K., Reinhardt R.
    BMC Genomics 11:393-393(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ep1/96Imported.

Entry informationi

Entry nameiD0FRY7_ERWPE
AccessioniPrimary (citable) accession number: D0FRY7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3