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D0FRY7 (D0FRY7_ERWPE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2531Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3011Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D0FRY7 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: CAAEF0626C690AED

FASTA35638,705
        10         20         30         40         50         60 
MSRPIVATIN RAALRQNLAI ARYTAGGARL WSVVKANAYG HGIDHVWQSL NETDGFALLN 

        70         80         90        100        110        120 
LEEAILLRER GWKKPILLLE GFFHPDDLQI LDRYRLTTSV HSNWQINALA QAKLSAPIDI 

       130        140        150        160        170        180 
YLKMNSGMNR LGFQPERVHG VWQKLRSLEN VGELTLMAHF ADAESAEGVA EPLKRIEQAA 

       190        200        210        220        230        240 
EGLECPRSLA NSAATLWHPQ THYDWVRPGI ILYGASPSGQ WQDIAGSGLQ PVMTLTSEVI 

       250        260        270        280        290        300 
AVQQLAAGSG VGYGSRYRAN CSQRIGVVAC GYADGYPRHA PTGTPIRVDG EKTQIVGAVS 

       310        320        330        340        350 
MDMITVDLTP CLQAGIGSQV ELWGDNVKID DVASASGTVG YELMCALAPR VPVRVV 

« Hide

References

[1]"Genome comparison of the epiphytic bacteria Erwinia billingiae and E. tasmaniensis with the pear pathogen E. pyrifoliae."
Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H., Knaust F., Geider K., Reinhardt R.
BMC Genomics 11:393-393(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ep1/96 EMBL CAX55402.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FP236842 Genomic DNA. Translation: CAX55402.1.
RefSeqYP_002648633.1. NC_012214.1.

3D structure databases

ProteinModelPortalD0FRY7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING634499.EpC_16230.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAX55402; CAX55402; EpC_16230.
GeneID8541143.
KEGGepy:EpC_16230.
PATRIC20421466. VBIErwPyr67807_1629.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031446.
KOK01775.
OMAMAHFADA.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycEPYR634499:GJIP-1682-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0FRY7_ERWPE
AccessionPrimary (citable) accession number: D0FRY7
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: February 19, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)