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D0EYG7

- D0EYG7_HUMAN

UniProt

D0EYG7 - D0EYG7_HUMAN

Protein
Submitted name:

Interleukin 7

Gene

IL7

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Biological processi

    1. bone resorption Source: Ensembl
    2. homeostasis of number of cells within a tissue Source: Ensembl
    3. immune response Source: InterPro
    4. negative regulation of catalytic activity Source: Ensembl
    5. negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
    6. positive regulation of B cell proliferation Source: Ensembl
    7. positive regulation of organ growth Source: Ensembl
    8. positive regulation of T cell differentiation Source: Ensembl
    9. regulation of gene expression Source: Ensembl
    10. T cell lineage commitment Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Interleukin 7Imported
    Gene namesi
    Name:IL7Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiD0EYG7.
    BgeeiD0EYG7.

    Family & Domainsi

    Family and domain databases

    InterProiIPR001181. IL-7.
    IPR018049. IL-7/IL-9_CS.
    IPR000226. IL-7/IL-9_fam.
    [Graphical view]
    PANTHERiPTHR10526. PTHR10526. 1 hit.
    PfamiPF01415. IL7. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001942. IL-7. 1 hit.
    PRINTSiPR00435. INTERLEUKIN7.
    SMARTiSM00127. IL7. 1 hit.
    [Graphical view]
    PROSITEiPS00255. INTERLEUKIN_7_9. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    D0EYG7-1 [UniParc]FASTAAdd to Basket

    « Hide

    DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN    50
    KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK 100
    PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK 150
    EH 152
    Length:152
    Mass (Da):17,387
    Last modified:November 24, 2009 - v1
    Checksum:iDCA15D4A22628F01
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ919059 mRNA. Translation: ACX53627.1.
    UniGeneiHs.591873.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GQ919059 mRNA. Translation: ACX53627.1 .
    UniGenei Hs.591873.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi IL7. human.
    NextBioi 35488931.

    Gene expression databases

    ArrayExpressi D0EYG7.
    Bgeei D0EYG7.

    Family and domain databases

    InterProi IPR001181. IL-7.
    IPR018049. IL-7/IL-9_CS.
    IPR000226. IL-7/IL-9_fam.
    [Graphical view ]
    PANTHERi PTHR10526. PTHR10526. 1 hit.
    Pfami PF01415. IL7. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001942. IL-7. 1 hit.
    PRINTSi PR00435. INTERLEUKIN7.
    SMARTi SM00127. IL7. 1 hit.
    [Graphical view ]
    PROSITEi PS00255. INTERLEUKIN_7_9. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Purification and characterization of human interleukin-7 expressed in Escherichia coli."
      Geng M., Zhang Y.-T., Chen Q., Wang F.-P., Xu L.-H., Ouyang D.-Y., He X.-H.
      Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiD0EYG7_HUMAN
    AccessioniPrimary (citable) accession number: D0EYG7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 24, 2009
    Last sequence update: November 24, 2009
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.