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D0EYG7

- D0EYG7_HUMAN

UniProt

D0EYG7 - D0EYG7_HUMAN

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Protein
Submitted name:

Interleukin 7

Gene

IL7

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. bone resorption Source: Ensembl
  2. homeostasis of number of cells within a tissue Source: Ensembl
  3. immune response Source: InterPro
  4. negative regulation of catalytic activity Source: Ensembl
  5. negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
  6. positive regulation of B cell proliferation Source: Ensembl
  7. positive regulation of organ growth Source: Ensembl
  8. positive regulation of T cell differentiation Source: Ensembl
  9. regulation of gene expression Source: Ensembl
  10. T cell lineage commitment Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 7Imported
Gene namesi
Name:IL7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiD0EYG7.
ExpressionAtlasiD0EYG7. baseline and differential.

Family & Domainsi

Family and domain databases

InterProiIPR001181. IL-7.
IPR018049. IL-7/IL-9_CS.
IPR000226. IL-7/IL-9_fam.
[Graphical view]
PANTHERiPTHR10526. PTHR10526. 1 hit.
PfamiPF01415. IL7. 1 hit.
[Graphical view]
PIRSFiPIRSF001942. IL-7. 1 hit.
PRINTSiPR00435. INTERLEUKIN7.
SMARTiSM00127. IL7. 1 hit.
[Graphical view]
PROSITEiPS00255. INTERLEUKIN_7_9. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D0EYG7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN
60 70 80 90 100
KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK
110 120 130 140 150
PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK

EH
Length:152
Mass (Da):17,387
Last modified:November 24, 2009 - v1
Checksum:iDCA15D4A22628F01
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GQ919059 mRNA. Translation: ACX53627.1.
UniGeneiHs.591873.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GQ919059 mRNA. Translation: ACX53627.1 .
UniGenei Hs.591873.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi IL7. human.
NextBioi 35488931.

Gene expression databases

Bgeei D0EYG7.
ExpressionAtlasi D0EYG7. baseline and differential.

Family and domain databases

InterProi IPR001181. IL-7.
IPR018049. IL-7/IL-9_CS.
IPR000226. IL-7/IL-9_fam.
[Graphical view ]
PANTHERi PTHR10526. PTHR10526. 1 hit.
Pfami PF01415. IL7. 1 hit.
[Graphical view ]
PIRSFi PIRSF001942. IL-7. 1 hit.
PRINTSi PR00435. INTERLEUKIN7.
SMARTi SM00127. IL7. 1 hit.
[Graphical view ]
PROSITEi PS00255. INTERLEUKIN_7_9. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Purification and characterization of human interleukin-7 expressed in Escherichia coli."
    Geng M., Zhang Y.-T., Chen Q., Wang F.-P., Xu L.-H., Ouyang D.-Y., He X.-H.
    Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD0EYG7_HUMAN
AccessioniPrimary (citable) accession number: D0EYG7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: October 29, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.