Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D0CB74

- D0CB74_ACIBA

UniProt

D0CB74 - D0CB74_ACIBA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Riboflavin biosynthesis protein RibD

Gene

ribD

Organism
Acinetobacter baumannii ATCC 19606 = CIP 70.34
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.UniRule annotation

Cofactori

Note: Binds 1 zinc ion.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi54 – 541Zinc; via pros nitrogenImported
Metal bindingi79 – 791ZincImported
Metal bindingi88 – 881ZincImported

GO - Molecular functioni

  1. 5-amino-6-(5-phosphoribosylamino)uracil reductase activity Source: InterPro
  2. diaminohydroxyphosphoribosylaminopyrimidine deaminase activity Source: InterPro
  3. NADP binding Source: InterPro
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. riboflavin biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported, OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Riboflavin biosynthesisUniRule annotation

Keywords - Ligandi

Metal-bindingUniRule annotationImported, NADPUniRule annotation, ZincUniRule annotationImported

Enzyme and pathway databases

UniPathwayiUPA00275; UER00401.
UPA00275; UER00402.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin biosynthesis protein RibDUniRule annotation
Gene namesi
Name:ribDImported
ORF Names:DJ41_1419Imported, F911_03682Imported, HMPREF0010_02004Imported
OrganismiAcinetobacter baumannii ATCC 19606 = CIP 70.34Imported
Taxonomic identifieri575584 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3ZPCX-ray2.20A/B1-361[»]
3ZPGX-ray1.99A1-361[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

In the C-terminal section; belongs to the HTP reductase family.UniRule annotation
In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.UniRule annotation

Family and domain databases

Gene3Di3.40.430.10. 1 hit.
InterProiIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR024072. DHFR-like_dom.
IPR004794. Eubact_RibD.
IPR011549. RibD_C.
IPR002734. RibDG_C.
[Graphical view]
PfamiPF00383. dCMP_cyt_deam_1. 1 hit.
PF01872. RibD_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006769. RibD. 1 hit.
SUPFAMiSSF53597. SSF53597. 1 hit.
SSF53927. SSF53927. 1 hit.
TIGRFAMsiTIGR00326. eubact_ribD. 1 hit.
TIGR00227. ribD_Cterm. 1 hit.
PROSITEiPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0CB74-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSELKQDQYW MQQAIELAKR GLYSTKPNPN VGCVIVKDDQ LIGEGFHPKA
60 70 80 90 100
GQPHAEVFAL RQAGEQAQGA TAYVTLEPCA HYGRTPPCAE ALVKAQVKKV
110 120 130 140 150
VVACPDPNPL VAGKGVQILK NAGIEVEIGI CEDLAAKLNQ GFLKAMSTGM
160 170 180 190 200
PYVRLKVASS LDGRTAMASG ESKWITGSAA RQDVQHWRAI SGAVITGIDT
210 220 230 240 250
VIADDCQLNV RSLHNIDIET VAQPKRVILD RRGRLPLTAK ILENPETVMV
260 270 280 290 300
MGPYRQELAD LGVIQLEIQP LKTLLQTLSK QYQIYDVLIE AGATLSSAFL
310 320 330 340 350
QEGLIDEMIS YVAPTLLGQS ARAMFNADFE YMAQQLRFKL LDVIQLDQDI
360
RLRLIPTQEK V
Length:361
Mass (Da):39,633
Last modified:November 24, 2009 - v1
Checksum:i13F6A01D4B132ACA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704574 Genomic DNA. Translation: EEX03756.1.
APRG01000018 Genomic DNA. Translation: ENW73393.1.
JMRY01000017 Genomic DNA. Translation: KFC02170.1.

Genome annotation databases

EnsemblBacteriaiEEX03756; EEX03756; HMPREF0010_02004.
ENW73393; ENW73393; F911_03682.
PATRICi24333545. VBIAciBau3967_1967.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704574 Genomic DNA. Translation: EEX03756.1 .
APRG01000018 Genomic DNA. Translation: ENW73393.1 .
JMRY01000017 Genomic DNA. Translation: KFC02170.1 .

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3ZPC X-ray 2.20 A/B 1-361 [» ]
3ZPG X-ray 1.99 A 1-361 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EEX03756 ; EEX03756 ; HMPREF0010_02004 .
ENW73393 ; ENW73393 ; F911_03682 .
PATRICi 24333545. VBIAciBau3967_1967.

Enzyme and pathway databases

UniPathwayi UPA00275 ; UER00401 .
UPA00275 ; UER00402 .

Family and domain databases

Gene3Di 3.40.430.10. 1 hit.
InterProi IPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR016193. Cytidine_deaminase-like.
IPR024072. DHFR-like_dom.
IPR004794. Eubact_RibD.
IPR011549. RibD_C.
IPR002734. RibDG_C.
[Graphical view ]
Pfami PF00383. dCMP_cyt_deam_1. 1 hit.
PF01872. RibD_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF006769. RibD. 1 hit.
SUPFAMi SSF53597. SSF53597. 1 hit.
SSF53927. SSF53927. 1 hit.
TIGRFAMsi TIGR00326. eubact_ribD. 1 hit.
TIGR00227. ribD_Cterm. 1 hit.
PROSITEi PS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 19606Imported.
  2. "Structure of diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase from Acinetobacter baumannii."
    Dawson A., Trumper P., Chrysostomou G., Hunter W.N.
    Acta Crystallogr. F 69:611-617(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS) IN COMPLEX WITH ZINC.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CIP 70.34Imported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 19606Imported.

Entry informationi

Entry nameiD0CB74_ACIBA
AccessioniPrimary (citable) accession number: D0CB74
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: November 26, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3