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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotationImported
ORF Names:F911_03144Imported, HMPREF0010_01329Imported
OrganismiAcinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841Imported
Taxonomic identifieri575584 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
Proteomesi
  • UP000013132 Componenti: Unassembled WGS sequence
  • UP000005740 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi575584.HMPREF0010_01329.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3WH4X-ray1.36A1-193[»]
4FOPX-ray1.86A1-193[»]
4FOTX-ray2.20A1-193[»]
4HOYX-ray1.78A1-193[»]
4IKOX-ray1.90A1-193[»]
4JWKX-ray1.87A1-193[»]
4JX9X-ray1.40A1-193[»]
4JY7X-ray1.90A1-193[»]
4LWQX-ray1.38A1-193[»]
4LWRX-ray1.10A1-193[»]
4OLJX-ray1.49A1-193[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD. Bacteria.
COG0193. LUCA.

Family and domain databases

Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0C9L6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNISLIVGL GNPGSEYAQT RHNAGFWFVE QLADKYGITL KNDPKFHGIS
60 70 80 90 100
GRGNIEGHDV RLLLPMTYMN RSGQSVVPFS KFYQIAPEAI LIAHDELDMN
110 120 130 140 150
PGVIRLKTGG GHGGHNGLRD IVPHIGPNFH RLRIGIGHPG SKERVSGHVL
160 170 180 190
GKAPSNEQSL MDGAIDHALS KVKLLVQGQV PQAMNQINAY KPA
Length:193
Mass (Da):20,938
Last modified:November 24, 2009 - v1
Checksum:i08025EF679FC28FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704573 Genomic DNA. Translation: EEX03935.1.
APRG01000016 Genomic DNA. Translation: ENW73725.1.
RefSeqiWP_000065593.1. NZ_KL810966.1.

Genome annotation databases

EnsemblBacteriaiEEX03935; EEX03935; HMPREF0010_01329.
ENW73725; ENW73725; F911_03144.
PATRICi24332185. VBIAciBau3967_1302.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704573 Genomic DNA. Translation: EEX03935.1.
APRG01000016 Genomic DNA. Translation: ENW73725.1.
RefSeqiWP_000065593.1. NZ_KL810966.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3WH4X-ray1.36A1-193[»]
4FOPX-ray1.86A1-193[»]
4FOTX-ray2.20A1-193[»]
4HOYX-ray1.78A1-193[»]
4IKOX-ray1.90A1-193[»]
4JWKX-ray1.87A1-193[»]
4JX9X-ray1.40A1-193[»]
4JY7X-ray1.90A1-193[»]
4LWQX-ray1.38A1-193[»]
4LWRX-ray1.10A1-193[»]
4OLJX-ray1.49A1-193[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi575584.HMPREF0010_01329.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEEX03935; EEX03935; HMPREF0010_01329.
ENW73725; ENW73725; F911_03144.
PATRICi24332185. VBIAciBau3967_1302.

Phylogenomic databases

eggNOGiENOG4108ZPD. Bacteria.
COG0193. LUCA.

Family and domain databases

Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 19606Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19606Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CIP 70.34Imported.

Entry informationi

Entry nameiD0C9L6_ACIBA
AccessioniPrimary (citable) accession number: D0C9L6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: July 6, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.