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D0C9L6 (D0C9L6_ACIBA) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. RuleBase RU000673

Sequence similarities

Belongs to the PTH family. RuleBase RU004320

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site221Phosphate PDB 4LWR
Binding site1071Acetate 1 PDB 4HOY PDB 4IKO PDB 4JY7
Binding site1111Acetate 1; via carbonyl oxygen PDB 4HOY PDB 4IKO PDB 4JY7
Binding site1161Phosphate PDB 4LWR
Binding site1311Acetate 1 PDB 4HOY PDB 4IKO PDB 4JY7

Sequences

Sequence LengthMass (Da)Tools
D0C9L6 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 08025EF679FC28FF

FASTA19320,938
        10         20         30         40         50         60 
MSNISLIVGL GNPGSEYAQT RHNAGFWFVE QLADKYGITL KNDPKFHGIS GRGNIEGHDV 

        70         80         90        100        110        120 
RLLLPMTYMN RSGQSVVPFS KFYQIAPEAI LIAHDELDMN PGVIRLKTGG GHGGHNGLRD 

       130        140        150        160        170        180 
IVPHIGPNFH RLRIGIGHPG SKERVSGHVL GKAPSNEQSL MDGAIDHALS KVKLLVQGQV 

       190 
PQAMNQINAY KPA 

« Hide

References

[1]"The Genome Sequence of Acinetobacter baumannii strain ATCC 19606."
The Broad Institute Genome Sequencing Platform
Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S. expand/collapse author list , Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C., Peleg A., Haas B., Nusbaum C., Birren B.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 19606 EMBL EEX03935.1.
[2]"The mode of inhibitor binding to peptidyl-tRNA hydrolase: binding studies and structure determination of unbound and bound peptidyl-tRNA hydrolase from Acinetobacter baumannii."
Kaushik S., Singh N., Yamini S., Singh A., Sinha M., Arora A., Kaur P., Sharma S., Singh T.P.
PLoS ONE 8:e67547-e67547(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS) IN COMPLEX WITH ACETATE.
[3]"The Genome Sequence of Acinetobacter baumannii CIP 70.34T."
The Broad Institute Genome Sequencing Platform, The Broad Institute Genome Sequencing Center for Infectious Disease
Cerqueira G., Feldgarden M., Courvalin P., Perichon B., Grillot-Courvalin C., Clermont D., Rocha E., Yoon E.-J., Nemec A., Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M. expand/collapse author list , Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.
Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CIP 70.34 EMBL ENW73725.1.
[4]"Crystal structure of native peptidyl t-RNA hydrolase from Acinetobacter baumannii at 1.38A resolution."
Kaushik S., Singh N., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.38 ANGSTROMS).
[5]"Crystal structure of the ternary complex of peptidyl tRNA hydrolase from Acinetobacter baumannii with cytosine arabinoside and phosphate ion at 1.1A resolution."
Kaushik S., Singh N., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JUL-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.10 ANGSTROMS) IN COMPLEX WITH PHOSPHATE.
[6]"Crystal structure of peptidyl t-RNA hydrolase from Acinetobacter baumannii in unbound state at 1.36A resolution."
Kaushik S., Singh N., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (AUG-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.36 ANGSTROMS).
[7]"Crystal structure of Arg119Gln mutant of Peptidyl-tRNA hydrolase from Acinetobacter Baumannii at 1.49 A resolution."
Sikarwar J., Dube D., Kaushik S., Sinha M., Kaur P., Sharma S., Singh T.P.
Submitted (JAN-2014) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.49 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG704573 Genomic DNA. Translation: EEX03935.1.
APRG01000016 Genomic DNA. Translation: ENW73725.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3WH4X-ray1.36A1-193[»]
4FOPX-ray1.86A1-193[»]
4FOTX-ray2.20A1-193[»]
4HOYX-ray1.78A1-193[»]
4IKOX-ray1.90A1-193[»]
4JWKX-ray1.87A1-193[»]
4JX9X-ray1.40A1-193[»]
4JY7X-ray1.90A1-193[»]
4LWQX-ray1.38A1-193[»]
4LWRX-ray1.10A1-193[»]
4OLJX-ray1.49A1-193[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEEX03935; EEX03935; HMPREF0010_01329.
ENW73725; ENW73725; F911_03144.
PATRIC24332185. VBIAciBau3967_1302.

Family and domain databases

Gene3D3.40.50.1470. 1 hit.
HAMAPMF_00083. Pept_tRNA_hydro_bact.
InterProIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERPTHR17224. PTHR17224. 1 hit.
PfamPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMSSF53178. SSF53178. 1 hit.
TIGRFAMsTIGR00447. pth. 1 hit.
PROSITEPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0C9L6_ACIBA
AccessionPrimary (citable) accession number: D0C9L6
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: April 16, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)