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D0B9E9 (D0B9E9_BRUME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphopantetheine adenylyltransferase 2 HAMAP MF_00151
EC=2.7.7.3 HAMAP MF_00151
Alternative name(s):
Dephospho-CoA pyrophosphorylase 2 HAMAP MF_00151
Pantetheine-phosphate adenylyltransferase 2 HAMAP MF_00151
Gene names
Name:coaD2 HAMAP MF_00151
ORF Names:BAWG_2857 EMBL EEW86804.1
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length164 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151

Catalytic activity

ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151

Subunit structure

Homohexamer By similarity. HAMAP MF_00151

Subcellular location

Cytoplasm By similarity HAMAP MF_00151.

Sequence similarities

Belongs to the bacterial CoaD family. HAMAP MF_00151

Sequences

Sequence LengthMass (Da)Tools
D0B9E9 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 73787866A6C89A5A

FASTA16417,399
        10         20         30         40         50         60 
MTIAIYAGSF DPVTNGHIDV LKGALRLADQ VIVAIGMHPG KKPLFSFDER VALIEASAKA 

        70         80         90        100        110        120 
VLHKDAARVS VIAFDGLVID AARKHGAQLM VRGLRDGTDL DYEMQMAGMN GTMAPELQTV 

       130        140        150        160 
FLPADPAVRT ITATLVRQIA SMGGDIKPFV PVAVAAALNT KFKS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		GG703780 Genomic DNA. Translation: EEW86804.1.
RefSeqNP_539803.1. NC_003317.1.

3D structure databases

ProteinModelPortalD0B9E9.
ModBaseSearch...

Protein-protein interaction databases

STRINGD0B9E9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1196597.
PATRIC17801960. VBIBruMel146950_3300.

Phylogenomic databases

OMAAMSDFEY.

Family and domain databases

HAMAPMF_00151. PPAT_bact.
[Tree]
InterProIPR004821. Cyt_trans-rel.
IPR004820. Cytidylyltransf.
IPR001980. LPS_biosynth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
PRINTSPR01020. LPSBIOSNTHSS.
TIGRFAMsTIGR01510. CoaD_prev_kdtB. 1 hit.
TIGR00125. Cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0B9E9_BRUME
AccessionPrimary (citable) accession number: D0B9E9
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: January 25, 2012
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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