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D0B5S8 (D0B5S8_BRUME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase 2 HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase 2 HAMAP MF_00323
Protoheme ferro-lyase 2 HAMAP MF_00323
Gene names
Name:hemH2 HAMAP MF_00323
ORF Names:BAWG_1449 EMBL EEW86970.1
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2221Iron By similarity HAMAP MF_00323
Metal binding3031Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
D0B5S8 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 5FE6C0F0EA435D32

FASTA35240,057
        10         20         30         40         50         60 
MSGTDKVRVN VSQTAQTPLH TSAKLPKVGV LLVNLGTPDG TSYGPMRRYL AEFLSDRRVI 

        70         80         90        100        110        120 
EWSRLIWYPI LYGIVLNTRP RRSGRLYDRI WNHENNESPL RTYTRAQGEK LAKALSDQPN 

       130        140        150        160        170        180 
VVVDWAMRYG QPSIESITDR LLQQGCERIV IFPLYPQYSA TTTATVNDKF FEALMKKRFM 

       190        200        210        220        230        240 
PAIRTVPSYE AEPVYIDALA RSVEKHLATL SFKPEVILTS YHGIPKSYSD KGDPYRQQCL 

       250        260        270        280        290        300 
ETTRLLRERL GLGEDEMRAT FQSRFGPEEW LQPYTDETVK ELAKNGVKSV AVLNPGFVAD 

       310        320        330        340        350 
CLETVDEIGN EAAEEFLENG GENFSHIPCL NDSEEGMKVI ETLVRRELLG WV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		GG703779 Genomic DNA. Translation: EEW86970.1.
RefSeqNP_540995.1. NC_003318.1.

3D structure databases

ProteinModelPortalD0B5S8.
ModBaseSearch...

Protein-protein interaction databases

STRINGD0B5S8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1197789.
PATRIC17798641. VBIBruMel146950_1664.

Phylogenomic databases

OMATIEEIGM.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0B5S8_BRUME
AccessionPrimary (citable) accession number: D0B5S8
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: January 25, 2012
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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