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D0B3M7 (D0B3M7_BRUME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Argininosuccinate lyase 2 HAMAP MF_00006
Short name=ASAL 2 HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006
Alternative name(s):
Arginosuccinase 2 HAMAP MF_00006
Gene names
Name:argH2 HAMAP MF_00006
ORF Names:BAWG_0109 EMBL EEW88001.1
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length466 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006

Subcellular location

Cytoplasm By similarity HAMAP MF_00006.

Sequence similarities

Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Arginine biosynthesis HAMAP MF_00006
   Cellular componentCytoplasm HAMAP MF_00006
   Molecular functionLyase HAMAP MF_00006 EMBL EEW88001.1
Gene Ontology (GO)
   Biological processarginine biosynthetic process via ornithine

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionargininosuccinate lyase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D0B3M7 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: A455713E39E31C66

FASTA46651,267
        10         20         30         40         50         60 
MSEQKSSNQM WGGRFASGPD AIMEEINASI GFDRKLYAQD IQGSLAHAAM LAKTGIIAAE 

        70         80         90        100        110        120 
DHKQIENGLK TIRKEIEEGK FTFSRKLEDI HMNIEARLAE LIGPAAGRLH TARSRNDQVA 

       130        140        150        160        170        180 
VDFRLWVKQE LEKTAAALKN LIEAFLERAE EHAATVMPGF THLQTAQPVT FGHHCMAYVE 

       190        200        210        220        230        240 
MFGRDLSRVR DAIERIDESP LGAAALAGTG FPIDRHMTAK ALGFREPTRN SLDSVSDRDY 

       250        260        270        280        290        300 
ALEFLSLAAI CAGHLSRLAE EIVIWSTPQF NFVRLSDAFS TGSSIMPQKK NPDAAELVRA 

       310        320        330        340        350        360 
KTGRINGSLV ALLTIMKGLP LAYSKDMQED KEQVFDAAEN LELAIAAMAG MVRDLTVNVA 

       370        380        390        400        410        420 
AMKKAAGSGY STATDLADWL VRTLGLPFRE AHHVTGRAVA LAESRKVDLA KLSLEELQSI 

       430        440        450        460 
NPAITAEVFG YLTVEKSVKS RQSFGGTAPQ EVRRQIRYWK KRIAKA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		GG703778 Genomic DNA. Translation: EEW88001.1.
RefSeqNP_539004.1. NC_003317.1.

3D structure databases

ProteinModelPortalD0B3M7.
SMRD0B3M7. Positions 19-465.
ModBaseSearch...

Protein-protein interaction databases

STRINGD0B3M7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1195798.
PATRIC17795522. VBIBruMel146950_1035.

Phylogenomic databases

OMAEDIHTVI.

Family and domain databases

HAMAPMF_00006. Arg_succ_lyase.
[Tree]
InterProIPR009049. Argininosuccinate_lyase.
IPR003031. D_crystallin.
IPR000362. Fumarate_lyase.
IPR020557. Fumarate_lyase_CS.
IPR008948. L-Aspartase-like.
IPR022761. Lyase1_N.
[Graphical view]
PANTHERPTHR11444:SF3. argH. 1 hit.
PfamPF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSPR00145. ARGSUCLYASE.
PR00149. FUMRATELYASE.
SUPFAMSSF48557. L-Aspartase-like. 1 hit.
TIGRFAMsTIGR00838. ArgH. 1 hit.
PROSITEPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0B3M7_BRUME
AccessionPrimary (citable) accession number: D0B3M7
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: January 25, 2012
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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