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D0B2M2 (D0B2M2_BRUME) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
NADH-quinone oxidoreductase subunit B HAMAP-Rule MF_01356

EC=1.6.99.5 HAMAP-Rule MF_01356
Alternative name(s):
NADH dehydrogenase I subunit B HAMAP-Rule MF_01356
NDH-1 subunit B HAMAP-Rule MF_01356
Gene names
Name:nuoB HAMAP-Rule MF_01356
ORF Names:BAWG_1052 EMBL EEW88944.1
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity. HAMAP-Rule MF_01356

Catalytic activity

NADH + quinone = NAD+ + quinol. HAMAP-Rule MF_01356

Cofactor

Binds 1 4Fe-4S cluster By similarity. HAMAP-Rule MF_01356

Subunit structure

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex By similarity. HAMAP-Rule MF_01356

Subcellular location

Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP-Rule MF_01356.

Sequence similarities

Belongs to the complex I 20 kDa subunit family. RuleBase RU004464 HAMAP-Rule MF_01356

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding791Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01356
Metal binding801Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01356
Metal binding1441Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01356
Metal binding1741Iron-sulfur (4Fe-4S) By similarity HAMAP-Rule MF_01356

Sequences

Sequence LengthMass (Da)Tools
D0B2M2 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 65410FA2F51B8DC6

FASTA20021,664
        10         20         30         40         50         60 
MEEGGAGMGL TGTNTTLVAP QPKGILDPRT GKPVGSDDAF FNDLNGELSD KGFIVTSADA 

        70         80         90        100        110        120 
LITWARTGSL MWMTFGLACC AVEMMHISMP RYDAERFGIA PRASPRQSDV MIVAGTLTNK 

       130        140        150        160        170        180 
MAPALRKVYD QMPEPRYVIS MGSCANGGGY YHYSYSVVRG CDRVVPVDIY VPGCPPTAEA 

       190        200 
LLYGILLLQK KIRRTGTIER 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG703778 Genomic DNA. Translation: EEW88944.1.
RefSeqNP_540074.1. NC_003317.1.

3D structure databases

ProteinModelPortalD0B2M2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEEW88944; EEW88944; BAWG_1052.
GeneID1196868.
KEGGbme:BMEI1157.
PATRIC17797704. VBIBruMel146950_0667.

Phylogenomic databases

eggNOGCOG0377.
KOK00331.
OMANNSAEYV.

Enzyme and pathway databases

BioCycBMEL224914:GCJ0-1192-MONOMER.

Family and domain databases

Gene3D3.40.50.700. 1 hit.
HAMAPMF_01356. NDH1_NuoB.
InterProIPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR006138. NADH_UQ_OxRdtase_20Kd_su.
[Graphical view]
PfamPF01058. Oxidored_q6. 1 hit.
[Graphical view]
TIGRFAMsTIGR01957. nuoB_fam. 1 hit.
PROSITEPS01150. COMPLEX1_20K. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0B2M2_BRUME
AccessionPrimary (citable) accession number: D0B2M2
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: June 11, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)