D0AZT7 (D0AZT7_BRUAO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134
ORF Names:	BAUG_2402 EMBL EEW79533.1

Organism

Brucella abortus NCTC 8038 EMBL EEW79533.1

Taxonomic identifier

575591 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134 SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134 SAAS SAAS013798
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134 SAAS SAAS013798
Molecular function	Decarboxylase HAMAP MF_00134 SAAS SAAS013798 Lyase
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D0AZT7 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 7BDF1668C6EAEC55	FASTA	268	29,269
	10 20 30 40 50 60 MSTDILRKIE AYKREEIAAA KARLALDELK ARTRDQSAPR GFLKALEAKR AAGQFALIAE 70 80 90 100 110 120 IKKASPSKGL IRPDFDPPAL AKAYEEGGAA CLSVLTDTPS FQGAPEFLTA ARQACSLPAL 130 140 150 160 170 180 RKDFLFDPYQ VYEARSWGAD CILIIMASVD DDLAKELEDT AFALGMDALI EVHDEAEMER 190 200 210 220 230 240 ALKLSSRLLG VNNRNLRSFE VNLAVSERLA KMAPSDRLLV GESGIFTHED CLRLEKSGIG 250 260 TFLIGESLMR QHDVAAATRA LLTGAEKL

References

[1]

"The Genome Sequence of Brucella abortus NCTC 8038." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Sangari F.J., Nusbaum C., Galagan J., Birren B. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: NCTC 8038 EMBL EEW79533.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG703765 Genomic DNA. Translation: EEW79533.1.
3D structure databases
ProteinModelPortal	D0AZT7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	24162758. VBIBruAbo97623_2712.
Family and domain databases
HAMAP	MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D0AZT7_BRUAO

Accession

Primary (citable) accession number: D0AZT7

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	December 14, 2011
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)