C9ZF77 (C9ZF77_STRSW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alkyl hydroperoxide reductase AhpD HAMAP MF_01676
EC=1.11.1.15 HAMAP MF_01676

Alternative name(s):
Alkylhydroperoxidase AhpD HAMAP MF_01676

Gene names

Name:	ahpD HAMAP MF_01676 EMBL CBG70461.1
Ordered Locus Names:	SCAB_33641

Organism

Streptomyces scabies (strain 87.22) (Streptomyces scabiei) [Complete proteome] [HAMAP]

Taxonomic identifier

680198 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity By similarity. HAMAP MF_01676 SAAS SAAS004674
Catalytic activity	2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. HAMAP MF_01676 SAAS SAAS004674
Subunit structure	Homotrimer By similarity. HAMAP MF_01676
Sequence similarities	Belongs to the AhpD family. HAMAP MF_01676

Ontologies

Keywords
Domain	Redox-active center HAMAP MF_01676 SAAS SAAS004674
Molecular function	Antioxidant HAMAP MF_01676 SAAS SAAS004674 Oxidoreductase Peroxidase HAMAP MF_01676 SAAS SAAS004674
PTM	Disulfide bond HAMAP MF_01676 SAAS SAAS004674
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alkyl hydroperoxide reductase activity Inferred from electronic annotation. Source: HAMAP peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW peroxiredoxin activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	131	1	Proton donor By similarity HAMAP MF_01676
	Active site	134	1	Cysteine sulfenic acid (-SOH) intermediate By similarity HAMAP MF_01676
Amino acid modifications
	Disulfide bond	131 ↔ 134		Alternate By similarity HAMAP MF_01676
	Disulfide bond	134		Interchain (with AhpC); in linked form By similarity HAMAP MF_01676

Sequences

	Sequence		Length	Mass (Da)
	C9ZF77 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 99758D50CEFFB0BD	FASTA	177	18,904
	10 20 30 40 50 60 MPLDTLRSAI PDYAGDLRRN LDAVLGDSGL SEQQVWGTVL ASAIASRSAP VLRELAPEAR 70 80 90 100 110 120 ARLSPEAYTA AKSAAAAMAL SNVFFRTRHL LSDHAYGELR TGLRMKVLGD PGVDRVDYEL 130 140 150 160 170 WALAVSAINA CGACLDSHEQ ALRRAGVGRE TVQEAFRIAS VIQAVGVTLE TEAVLSE

References

[1]	"Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions." Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J., Loria R. Mol. Plant Microbe Interact. 23:161-175(2010) [PubMed: 20064060] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 87.22 EMBL CBG70461.1.
[2]	Bentley S.D. Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 87.22 EMBL CBG70461.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN554889 Genomic DNA. Translation: CBG70461.1.
RefSeq	YP_003489012.1. NC_013929.1.
3D structure databases
ProteinModelPortal	C9ZF77.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8840300.
GenomeReviews	Gene locus SCAB_33641 in contig FN554889_GR.
KEGG	scb:SCAB_33641.
PATRIC	35322372. VBIStrSca144334_3287.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	RAGLRMN.
Family and domain databases
HAMAP	MF_01676. AhpD. [Tree]
InterPro	IPR004674. AhpD. IPR004675. AhpD_core. IPR003779. CMD. [Graphical view]
KO	K04756.
Pfam	PF02627. CMD. 1 hit. [Graphical view]
TIGRFAMs	TIGR00777. AhpD. 1 hit. TIGR00778. AhpD_dom. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C9ZF77_STRSW

Accession

Primary (citable) accession number: C9ZF77

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)