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C9ZCP3 (C9ZCP3_STRSW) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:SCAB_78681 EMBL CBG74832.1
OrganismStreptomyces scabies (strain 87.22) (Streptomyces scabiei) [Complete proteome] [HAMAP] EMBL CBG74832.1
Taxonomic identifier680198 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length512 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407 RuleBase RU000617

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2101N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2081ATP By similarity HAMAP-Rule MF_00407
Binding site2151ATP By similarity HAMAP-Rule MF_00407
Binding site2301ATP By similarity HAMAP-Rule MF_00407
Binding site2591ATP By similarity HAMAP-Rule MF_00407
Binding site2991ATP By similarity HAMAP-Rule MF_00407
Binding site3741ATP By similarity HAMAP-Rule MF_00407
Binding site3801ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
C9ZCP3 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: EF258D84F913D2FC

FASTA51255,286
        10         20         30         40         50         60 
MLFARLARVS QEIAATSARS RKTALLADLF RDAGEEDVPI VIPYLAGRLP QGRLGIGWKV 

        70         80         90        100        110        120 
LDQRIPPAGT ATLTVREVDA RLTAIGAVTG TGSQTERRRL VGALLAAATE DEQRYLVGLL 

       130        140        150        160        170        180 
TGEVRQGALD ALAVEGLAGA TGAPAADVRR AVMLAGSLQT VARALLAEGP RALEGFRLTV 

       190        200        210        220        230        240 
GRPVQPMLAH SAPSVAEAVA KLGVCAVEEK LDGIRVQLHR DGGDVRLYTR TLDDITDRLP 

       250        260        270        280        290        300 
ELTSAALGLR GERFILDGEV IAFDGNGRPR SFQETAGRVG SRLDVATAAR QVPVSPVFFD 

       310        320        330        340        350        360 
ALSVDGQDLL DLPFTERHAV LARLVPEPMR VRRTLVTGPD DLPEAERFLT DTLERGHEGV 

       370        380        390        400        410        420 
VLKALDAPYS AGRRGASWLK VKPVHTLDLV VLAAEWGHGR RTGRLSNLHL GARTADGAFA 

       430        440        450        460        470        480 
MLGKTFKGMT DALLAWQTER LTELAVEEHR WGVTVRPELV VEIAYDGLQR STRYPAGVTL 

       490        500        510 
RFARVIRYRE DKTPGEADTV EALLSAHPEV TR 

« Hide

References

[1]"Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions."
Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J., Loria R.
Mol. Plant Microbe Interact. 23:161-175(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 87.22 EMBL CBG74832.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN554889 Genomic DNA. Translation: CBG74832.1.
RefSeqYP_003493363.1. NC_013929.1.

3D structure databases

ProteinModelPortalC9ZCP3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBG74832; CBG74832; SCAB_78681.
GeneID8844530.
KEGGscb:SCAB_78681.
PATRIC35331449. VBIStrSca144334_7758.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000036008.
KOK01971.
OMAVPIVIPY.

Enzyme and pathway databases

BioCycSSCA680198:GJ76-7705-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC9ZCP3_STRSW
AccessionPrimary (citable) accession number: C9ZCP3
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: June 11, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)