C9YWY8 (C9YWY8_STRSW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859
EC=2.1.1.174 HAMAP MF_01859

Alternative name(s):
23S rRNA m2G1835 methyltransferase HAMAP MF_01859
rRNA (guanine-N(2)-)-methyltransferase RlmG HAMAP MF_01859

Gene names

Name:	rlmG HAMAP MF_01859
Ordered Locus Names:	SCAB_82901

Organism

Streptomyces scabies (strain 87.22) (Streptomyces scabiei) [Complete proteome] [HAMAP]

Taxonomic identifier

680198 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	386 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859 SAAS SAAS007848
Catalytic activity	S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859 SAAS SAAS007848
Subcellular location	Cytoplasm By similarity HAMAP MF_01859 SAAS SAAS007848.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family. HAMAP MF_01859

Ontologies

Keywords
Biological process	rRNA processing HAMAP MF_01859 SAAS SAAS007848
Cellular component	Cytoplasm HAMAP MF_01859 SAAS SAAS007848
Ligand	S-adenosyl-L-methionine HAMAP MF_01859 SAAS SAAS007848
Molecular function	Methyltransferase HAMAP MF_01859 SAAS SAAS007848 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C9YWY8 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 503C815A564D0D4F	FASTA	386	41,724
	10 20 30 40 50 60 MSDRMTAPWG EYTLTRFPED PRDLLRAWDA SDAYLLRHLA ESGTRLDGTV VIVGDRWGAL 70 80 90 100 110 120 TTALAGYGPT QITDSFLSRE ATRANLERGG VDPDAVRLLT TRDTPPDRVD VLLVRIPKSL 130 140 150 160 170 180 ALLEDQLHRL APAVHEGTVV IGTGMVKEIH TSTLRLFERI LGPTRTSLAR QKARLVLCTP 190 200 210 220 230 240 DAEVLAARGD DPWPYTYRLP DDVGVLAGRA VVNHAGVFCA DRLDIGTRFF LRQLPQAPAG 250 260 270 280 290 300 GRVVDLGCGN GVVGTAVALA GPDAEVVFVD ESYQAVASAR ATYEANRPGA DPGAEFLVGD 310 320 330 340 350 360 GLEDFPAGSV DLVLNNPPFH SHQATTDATA RRMFTGARRA LRPGGELWVV GNRHLGYHVT 370 380 LRRIFGNGEV VASDPRFVVL RAVRAG

References

[1]	"Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions." Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J., Loria R. Mol. Plant Microbe Interact. 23:161-175(2010) [PubMed: 20064060] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 87.22 EMBL CBG75243.1.
[2]	Bentley S.D. Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 87.22 EMBL CBG75243.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN554889 Genomic DNA. Translation: CBG75243.1.
RefSeq	YP_003493767.1. NC_013929.1.
3D structure databases
ProteinModelPortal	C9YWY8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8845863.
GenomeReviews	Gene locus SCAB_82901 in contig FN554889_GR.
KEGG	scb:SCAB_82901.
PATRIC	35332281. VBIStrSca144334_8174.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NRHLGYH.
Family and domain databases
HAMAP	MF_01859. 23SrRNA_methyltr_G. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
PROSITE	PS00092. N6_MTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C9YWY8_STRSW

Accession

Primary (citable) accession number: C9YWY8

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)