Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoadenosine phosphosulfate reductase

Gene

cysH

Organism
Streptomyces scabies (strain 87.22) (Streptomyces scabiei)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Reduction of activated sulfate into sulfite.UniRule annotation

Catalytic activityi

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSSCA680198:GJ76-1877-MONOMER.
UniPathwayiUPA00140; UER00206.
UPA00140; UER00206.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoadenosine phosphosulfate reductaseUniRule annotation (EC:1.8.4.8UniRule annotation)
Alternative name(s):
3'-phosphoadenylylsulfate reductaseUniRule annotation
PAPS reductase, thioredoxin dependentUniRule annotation
PAPS sulfotransferaseUniRule annotation
PAdoPS reductaseUniRule annotation
Gene namesi
Name:cysHUniRule annotationImported
Ordered Locus Names:SCAB_19791Imported
OrganismiStreptomyces scabies (strain 87.22) (Streptomyces scabiei)Imported
Taxonomic identifieri680198 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000001444 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PAPS reductase family. CysH subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000249397.
KOiK00390.
OMAiCVTSSMA.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00063. CysH.
InterProiIPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFiPIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMsiTIGR00434. cysH. 1 hit.

Sequencei

Sequence statusi: Complete.

C9YUJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAVQADSGT SASSPDTAGQ DEARRAELRA LAEQAGRDLE DASALEILQW
60 70 80 90 100
AADTFGERFC VTSSMEDAVV AHLASRARPG VDVVFLDTGY HFPETIGTRD
110 120 130 140 150
AVEAVMDVNL VTITPRQTVA EQDAEYGPRL HDRDPDLCCF LRKVKPLEEG
160 170 180 190 200
LARFDAWATG LRRDESASRA DTPVVGWDDK RGKVKVSPIA RWTQDDVDAY
210 220 230 240 250
VAEHGVLTNP LLMDGYASVG CAPCTRRVAP GEDARAGRWA GNAKTECGLH

L
Length:251
Mass (Da):27,186
Last modified:November 24, 2009 - v1
Checksum:i3A5263ADAA476ECC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN554889 Genomic DNA. Translation: CBG69099.1.
RefSeqiWP_012999823.1. NC_013929.1.
YP_003487664.1. NC_013929.1.

Genome annotation databases

EnsemblBacteriaiCBG69099; CBG69099; SCAB_19791.
KEGGiscb:SCAB_19791.
PATRICi35319654. VBIStrSca144334_1941.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN554889 Genomic DNA. Translation: CBG69099.1.
RefSeqiWP_012999823.1. NC_013929.1.
YP_003487664.1. NC_013929.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBG69099; CBG69099; SCAB_19791.
KEGGiscb:SCAB_19791.
PATRICi35319654. VBIStrSca144334_1941.

Phylogenomic databases

HOGENOMiHOG000249397.
KOiK00390.
OMAiCVTSSMA.

Enzyme and pathway databases

UniPathwayiUPA00140; UER00206.
UPA00140; UER00206.
BioCyciSSCA680198:GJ76-1877-MONOMER.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00063. CysH.
InterProiIPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFiPIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMsiTIGR00434. cysH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions."
    Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J., Loria R.
    Mol. Plant Microbe Interact. 23:161-175(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 87.22Imported.

Entry informationi

Entry nameiC9YUJ9_STRSW
AccessioniPrimary (citable) accession number: C9YUJ9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: April 29, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.