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Protein
Submitted name:

Putative D-3-phosphoglycerate dehydrogenase

Gene

serA

Organism
Peptoclostridium difficile (strain R20291) (Clostridium difficile)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciCDIF645463:GJP4-923-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative D-3-phosphoglycerate dehydrogenaseImported
Gene namesi
Name:serAImported
Ordered Locus Names:CDR20291_0848Imported
OrganismiPeptoclostridium difficile (strain R20291) (Clostridium difficile)Imported
Taxonomic identifieri645463 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
ProteomesiUP000002070 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliC9YJU8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0111.
HOGENOMiHOG000136700.
OMAiHDHIKVI.
OrthoDBiEOG6VXFC3.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9YJU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYNILVTDGI EKEAARKLRE LDFNVIEQFY EKDVLGDKLK DVDVLVVRSA
60 70 80 90 100
TKVTKDVIDK ALEGKKLKLI VRGGVGLDNI DVKYAQANGI KVMNTPNASS
110 120 130 140 150
ISVAELTIGQ LFVLARFINT ANVTMRDGKW EKKKYKGTEI NGKTLGLIGF
160 170 180 190 200
GRIAKEVAKR AELLGMNVIY TDIMGEAQGF NNYKFCDMEE VLENADFLSL
210 220 230 240 250
HIPFDKNKGA VITEKEINKM KKGAYLINCA RGGLVDEKDL LKALDEGKLS
260 270 280 290 300
AAAIDVYEQE PTLNLDLVNH PRVSPTPHIG ASTVEAQERI GDEIVNVIQD
310
FFLDFNNLIG VAL
Length:313
Mass (Da):34,666
Last modified:November 24, 2009 - v1
Checksum:i49503EA420A04067
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN545816 Genomic DNA. Translation: CBE02943.1.

Genome annotation databases

EnsemblBacteriaiCBE02943; CBE02943; CDR20291_0848.
PATRICi19455510. VBICloDif78408_0910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN545816 Genomic DNA. Translation: CBE02943.1.

3D structure databases

ProteinModelPortaliC9YJU8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBE02943; CBE02943; CDR20291_0848.
PATRICi19455510. VBICloDif78408_0910.

Phylogenomic databases

eggNOGiCOG0111.
HOGENOMiHOG000136700.
OMAiHDHIKVI.
OrthoDBiEOG6VXFC3.

Enzyme and pathway databases

BioCyciCDIF645463:GJP4-923-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium."
    Stabler R.A., He M., Dawson L., Martin M., Valiente E., Corton C., Lawley T.D., Sebaihia M., Quail M.A., Rose G., Gerding D.N., Gibert M., Popoff M.R., Parkhill J., Dougan G., Wren B.W.
    Genome Biol. 10:R102.1-R102.15(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R20291Imported.

Entry informationi

Entry nameiC9YJU8_PEPDR
AccessioniPrimary (citable) accession number: C9YJU8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: July 22, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.