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C9XK75

- C9XK75_PEPDC

UniProt

C9XK75 - C9XK75_PEPDC

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Protein
Submitted name:

PTS system, beta-glucoside-specific IIabc component

Gene
bglF, CD196_0373
Organism
Peptoclostridium difficile (strain CD196) (Clostridium difficile)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.SAAS annotations

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
  2. protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Source: InterPro

GO - Biological processi

  1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotations, Transferase

Keywords - Biological processi

Phosphotransferase systemSAAS annotations, Sugar transportSAAS annotations, Transport

Enzyme and pathway databases

BioCyciCDIF645462:GJED-461-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
PTS system, beta-glucoside-specific IIabc componentImported
Gene namesi
Name:bglFImported
Ordered Locus Names:CD196_0373Imported
OrganismiPeptoclostridium difficile (strain CD196) (Clostridium difficile)Imported
Taxonomic identifieri645462 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
ProteomesiUP000002068: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotations, Membrane

Interactioni

Protein-protein interaction databases

STRINGi645462.CD196_0373.

Family & Domainsi

Sequence similaritiesi

Contains PTS EIIA type-1 domain.SAAS annotations
Contains PTS EIIA type-domain.SAAS annotations
Contains PTS EIIB type-1 domain.SAAS annotations
Contains PTS EIIB type-domain.SAAS annotations
Contains PTS EIIC type-1 domain.SAAS annotations
Contains PTS EIIC type-domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

eggNOGiCOG1263.
HOGENOMiHOG000102023.
KOiK02755.
K02756.
K02757.
OMAiIEHCSTR.
OrthoDBiEOG6ND0GQ.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR011297. PTS_IIABC_b_glu.
IPR001996. PTS_IIB_1.
[Graphical view]
PfamiPF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00830. PTBA. 1 hit.
TIGR01995. PTS-II-ABC-beta. 1 hit.
PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9XK75-1 [UniParc]FASTAAdd to Basket

« Hide

MNYKKTAIDI IEQVGGSKNI LALEHCSTRL RFKLIDRSKV NQDALKKVQG    50
VMSIVNGAQF QVVIGNSVVD VYDEILKVCP LDTNDSTVKT EEKINLGTRF 100
IEFIINIFQP LIFAIAGAGI LKSLLMLLAM FNILKSDSTI YTLLVAISDA 150
TFYFLPLMVA VTTANVLKCN RLVAIAAVGY LLLPATTTAL SEGVELFGFT 200
IPNIAYNAQV FPAILCVSFL ATMEKIFNKY SPKPIRTFFV PMMSLAITVP 250
ITLTILGPLG YNVGTIFTTI ILFLYNKMGF LVVGLLAAFL PFMVATGMHK 300
ALIPYSINTI GKLGYEALYM TSSLAHNISE SGACFAVALR TKDETLKQTA 350
LSAGISALMG ITEPALYGIT LQHKRAMLGV VFSSAISGTF LGLFAVKGFV 400
IVGPGLASMS MFIDPNNGNN LIFASIGFVI AILGSFIITL IIWKEDTNTV 450
ESSIGDVVEE ELEEEKEVNI LVTPVEGKVI DLSKVNDELF ASKTLGDGVA 500
IIPTNGNLYA PCDSEVVMLF ETKHAIGLRT KNGAEILIHI GINTVSMNGD 550
GFKTFVKTGD NVKEGDLLIQ FDLDKISHAN LDSTVMIVNN NGADYAYKVL 600
NQSYGNVKKG SILFDVKGGI 620
Length:620
Mass (Da):67,047
Last modified:November 24, 2009 - v1
Checksum:iF93E16A65F8F271F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN538970 Genomic DNA. Translation: CBA60733.1.
RefSeqiYP_003213420.1. NC_013315.1.

Genome annotation databases

EnsemblBacteriaiCBA60733; CBA60733; CD196_0373.
GeneIDi8463494.
KEGGicdc:CD196_0373.
PATRICi19446922. VBICloDif125228_0384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN538970 Genomic DNA. Translation: CBA60733.1 .
RefSeqi YP_003213420.1. NC_013315.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 645462.CD196_0373.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBA60733 ; CBA60733 ; CD196_0373 .
GeneIDi 8463494.
KEGGi cdc:CD196_0373.
PATRICi 19446922. VBICloDif125228_0384.

Phylogenomic databases

eggNOGi COG1263.
HOGENOMi HOG000102023.
KOi K02755.
K02756.
K02757.
OMAi IEHCSTR.
OrthoDBi EOG6ND0GQ.

Enzyme and pathway databases

BioCyci CDIF645462:GJED-461-MONOMER.

Family and domain databases

Gene3Di 3.30.1360.60. 1 hit.
InterProi IPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR011297. PTS_IIABC_b_glu.
IPR001996. PTS_IIB_1.
[Graphical view ]
Pfami PF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view ]
SUPFAMi SSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsi TIGR00830. PTBA. 1 hit.
TIGR01995. PTS-II-ABC-beta. 1 hit.
PROSITEi PS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium."
    Stabler R.A., He M., Dawson L., Martin M., Valiente E., Corton C., Lawley T.D., Sebaihia M., Quail M.A., Rose G., Gerding D.N., Gibert M., Popoff M.R., Parkhill J., Dougan G., Wren B.W.
    Genome Biol. 10:R102.1-R102.15(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CD196Imported.

Entry informationi

Entry nameiC9XK75_PEPDC
AccessioniPrimary (citable) accession number: C9XK75
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: September 3, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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