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C9XK75

- C9XK75_PEPDC

UniProt

C9XK75 - C9XK75_PEPDC

Protein
Submitted name:

PTS system, beta-glucoside-specific IIabc component

Gene

bglF

Organism
Peptoclostridium difficile (strain CD196) (Clostridium difficile)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (24 Nov 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.SAAS annotation

    GO - Molecular functioni

    1. kinase activity Source: UniProtKB-KW
    2. protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Source: InterPro

    GO - Biological processi

    1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseSAAS annotation, Transferase

    Keywords - Biological processi

    Phosphotransferase systemSAAS annotation, Sugar transportSAAS annotation, Transport

    Enzyme and pathway databases

    BioCyciCDIF645462:GJED-461-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PTS system, beta-glucoside-specific IIabc componentImported
    Gene namesi
    Name:bglFImported
    Ordered Locus Names:CD196_0373Imported
    OrganismiPeptoclostridium difficile (strain CD196) (Clostridium difficile)Imported
    Taxonomic identifieri645462 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
    ProteomesiUP000002068: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Interactioni

    Protein-protein interaction databases

    STRINGi645462.CD196_0373.

    Family & Domainsi

    Sequence similaritiesi

    Contains PTS EIIA type-1 domain.SAAS annotation
    Contains PTS EIIA type-domain.SAAS annotation
    Contains PTS EIIB type-1 domain.SAAS annotation
    Contains PTS EIIB type-domain.SAAS annotation
    Contains PTS EIIC type-1 domain.SAAS annotation
    Contains PTS EIIC type-domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    eggNOGiCOG1263.
    HOGENOMiHOG000102023.
    KOiK02755.
    K02756.
    K02757.
    OMAiIEHCSTR.
    OrthoDBiEOG6ND0GQ.

    Family and domain databases

    Gene3Di3.30.1360.60. 1 hit.
    InterProiIPR011055. Dup_hybrid_motif.
    IPR018113. PTrfase_EIIB_Cys.
    IPR001127. PTS_EIIA_1_perm.
    IPR003352. PTS_EIIC.
    IPR013013. PTS_EIIC_1.
    IPR011297. PTS_IIABC_b_glu.
    IPR001996. PTS_IIB_1.
    [Graphical view]
    PfamiPF00358. PTS_EIIA_1. 1 hit.
    PF00367. PTS_EIIB. 1 hit.
    PF02378. PTS_EIIC. 1 hit.
    [Graphical view]
    SUPFAMiSSF51261. SSF51261. 1 hit.
    SSF55604. SSF55604. 1 hit.
    TIGRFAMsiTIGR00830. PTBA. 1 hit.
    TIGR01995. PTS-II-ABC-beta. 1 hit.
    PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
    PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
    PS51098. PTS_EIIB_TYPE_1. 1 hit.
    PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
    PS51103. PTS_EIIC_TYPE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C9XK75-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNYKKTAIDI IEQVGGSKNI LALEHCSTRL RFKLIDRSKV NQDALKKVQG    50
    VMSIVNGAQF QVVIGNSVVD VYDEILKVCP LDTNDSTVKT EEKINLGTRF 100
    IEFIINIFQP LIFAIAGAGI LKSLLMLLAM FNILKSDSTI YTLLVAISDA 150
    TFYFLPLMVA VTTANVLKCN RLVAIAAVGY LLLPATTTAL SEGVELFGFT 200
    IPNIAYNAQV FPAILCVSFL ATMEKIFNKY SPKPIRTFFV PMMSLAITVP 250
    ITLTILGPLG YNVGTIFTTI ILFLYNKMGF LVVGLLAAFL PFMVATGMHK 300
    ALIPYSINTI GKLGYEALYM TSSLAHNISE SGACFAVALR TKDETLKQTA 350
    LSAGISALMG ITEPALYGIT LQHKRAMLGV VFSSAISGTF LGLFAVKGFV 400
    IVGPGLASMS MFIDPNNGNN LIFASIGFVI AILGSFIITL IIWKEDTNTV 450
    ESSIGDVVEE ELEEEKEVNI LVTPVEGKVI DLSKVNDELF ASKTLGDGVA 500
    IIPTNGNLYA PCDSEVVMLF ETKHAIGLRT KNGAEILIHI GINTVSMNGD 550
    GFKTFVKTGD NVKEGDLLIQ FDLDKISHAN LDSTVMIVNN NGADYAYKVL 600
    NQSYGNVKKG SILFDVKGGI 620
    Length:620
    Mass (Da):67,047
    Last modified:November 24, 2009 - v1
    Checksum:iF93E16A65F8F271F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN538970 Genomic DNA. Translation: CBA60733.1.
    RefSeqiYP_003213420.1. NC_013315.1.

    Genome annotation databases

    EnsemblBacteriaiCBA60733; CBA60733; CD196_0373.
    GeneIDi8463494.
    KEGGicdc:CD196_0373.
    PATRICi19446922. VBICloDif125228_0384.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN538970 Genomic DNA. Translation: CBA60733.1 .
    RefSeqi YP_003213420.1. NC_013315.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 645462.CD196_0373.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBA60733 ; CBA60733 ; CD196_0373 .
    GeneIDi 8463494.
    KEGGi cdc:CD196_0373.
    PATRICi 19446922. VBICloDif125228_0384.

    Phylogenomic databases

    eggNOGi COG1263.
    HOGENOMi HOG000102023.
    KOi K02755.
    K02756.
    K02757.
    OMAi IEHCSTR.
    OrthoDBi EOG6ND0GQ.

    Enzyme and pathway databases

    BioCyci CDIF645462:GJED-461-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1360.60. 1 hit.
    InterProi IPR011055. Dup_hybrid_motif.
    IPR018113. PTrfase_EIIB_Cys.
    IPR001127. PTS_EIIA_1_perm.
    IPR003352. PTS_EIIC.
    IPR013013. PTS_EIIC_1.
    IPR011297. PTS_IIABC_b_glu.
    IPR001996. PTS_IIB_1.
    [Graphical view ]
    Pfami PF00358. PTS_EIIA_1. 1 hit.
    PF00367. PTS_EIIB. 1 hit.
    PF02378. PTS_EIIC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51261. SSF51261. 1 hit.
    SSF55604. SSF55604. 1 hit.
    TIGRFAMsi TIGR00830. PTBA. 1 hit.
    TIGR01995. PTS-II-ABC-beta. 1 hit.
    PROSITEi PS51093. PTS_EIIA_TYPE_1. 1 hit.
    PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
    PS51098. PTS_EIIB_TYPE_1. 1 hit.
    PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
    PS51103. PTS_EIIC_TYPE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium."
      Stabler R.A., He M., Dawson L., Martin M., Valiente E., Corton C., Lawley T.D., Sebaihia M., Quail M.A., Rose G., Gerding D.N., Gibert M., Popoff M.R., Parkhill J., Dougan G., Wren B.W.
      Genome Biol. 10:R102.1-R102.15(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CD196Imported.

    Entry informationi

    Entry nameiC9XK75_PEPDC
    AccessioniPrimary (citable) accession number: C9XK75
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 24, 2009
    Last sequence update: November 24, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3