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Protein
Submitted name:

PTS system, beta-glucoside-specific IIabc component

Gene

bglF

Organism
Peptoclostridium difficile (strain CD196) (Clostridium difficile)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.SAAS annotation

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
  2. protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Source: InterPro

GO - Biological processi

  1. phosphoenolpyruvate-dependent sugar phosphotransferase system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

Phosphotransferase systemSAAS annotation, Sugar transportSAAS annotation, Transport

Enzyme and pathway databases

BioCyciCDIF645462:GJED-461-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
PTS system, beta-glucoside-specific IIabc componentImported
Gene namesi
Name:bglFImported
Ordered Locus Names:CD196_0373Imported
OrganismiPeptoclostridium difficile (strain CD196) (Clostridium difficile)Imported
Taxonomic identifieri645462 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
ProteomesiUP000002068 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi645462.CD196_0373.

Family & Domainsi

Sequence similaritiesi

Contains PTS EIIA type-1 domain.SAAS annotation
Contains PTS EIIB type-1 domain.SAAS annotation
Contains PTS EIIC type-1 domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiCOG1263.
HOGENOMiHOG000102023.
KOiK02755.
K02756.
K02757.
OrthoDBiEOG6ND0GQ.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR011297. PTS_IIABC_b_glu.
IPR001996. PTS_IIB_1.
[Graphical view]
PfamiPF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00830. PTBA. 1 hit.
TIGR01995. PTS-II-ABC-beta. 1 hit.
PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9XK75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYKKTAIDI IEQVGGSKNI LALEHCSTRL RFKLIDRSKV NQDALKKVQG
60 70 80 90 100
VMSIVNGAQF QVVIGNSVVD VYDEILKVCP LDTNDSTVKT EEKINLGTRF
110 120 130 140 150
IEFIINIFQP LIFAIAGAGI LKSLLMLLAM FNILKSDSTI YTLLVAISDA
160 170 180 190 200
TFYFLPLMVA VTTANVLKCN RLVAIAAVGY LLLPATTTAL SEGVELFGFT
210 220 230 240 250
IPNIAYNAQV FPAILCVSFL ATMEKIFNKY SPKPIRTFFV PMMSLAITVP
260 270 280 290 300
ITLTILGPLG YNVGTIFTTI ILFLYNKMGF LVVGLLAAFL PFMVATGMHK
310 320 330 340 350
ALIPYSINTI GKLGYEALYM TSSLAHNISE SGACFAVALR TKDETLKQTA
360 370 380 390 400
LSAGISALMG ITEPALYGIT LQHKRAMLGV VFSSAISGTF LGLFAVKGFV
410 420 430 440 450
IVGPGLASMS MFIDPNNGNN LIFASIGFVI AILGSFIITL IIWKEDTNTV
460 470 480 490 500
ESSIGDVVEE ELEEEKEVNI LVTPVEGKVI DLSKVNDELF ASKTLGDGVA
510 520 530 540 550
IIPTNGNLYA PCDSEVVMLF ETKHAIGLRT KNGAEILIHI GINTVSMNGD
560 570 580 590 600
GFKTFVKTGD NVKEGDLLIQ FDLDKISHAN LDSTVMIVNN NGADYAYKVL
610 620
NQSYGNVKKG SILFDVKGGI
Length:620
Mass (Da):67,047
Last modified:November 24, 2009 - v1
Checksum:iF93E16A65F8F271F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN538970 Genomic DNA. Translation: CBA60733.1.
RefSeqiYP_003213420.1. NC_013315.1.

Genome annotation databases

EnsemblBacteriaiCBA60733; CBA60733; CD196_0373.
KEGGicdc:CD196_0373.
PATRICi19446922. VBICloDif125228_0384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN538970 Genomic DNA. Translation: CBA60733.1.
RefSeqiYP_003213420.1. NC_013315.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi645462.CD196_0373.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBA60733; CBA60733; CD196_0373.
KEGGicdc:CD196_0373.
PATRICi19446922. VBICloDif125228_0384.

Phylogenomic databases

eggNOGiCOG1263.
HOGENOMiHOG000102023.
KOiK02755.
K02756.
K02757.
OrthoDBiEOG6ND0GQ.

Enzyme and pathway databases

BioCyciCDIF645462:GJED-461-MONOMER.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR011297. PTS_IIABC_b_glu.
IPR001996. PTS_IIB_1.
[Graphical view]
PfamiPF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00830. PTBA. 1 hit.
TIGR01995. PTS-II-ABC-beta. 1 hit.
PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium."
    Stabler R.A., He M., Dawson L., Martin M., Valiente E., Corton C., Lawley T.D., Sebaihia M., Quail M.A., Rose G., Gerding D.N., Gibert M., Popoff M.R., Parkhill J., Dougan G., Wren B.W.
    Genome Biol. 10:R102.1-R102.15(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CD196Imported.

Entry informationi

Entry nameiC9XK75_PEPDC
AccessioniPrimary (citable) accession number: C9XK75
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: April 1, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.