C9XE68 (C9XE68_SALTD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartate carbamoyltransferase regulatory chain HAMAP-Rule MF_00002

Gene names

Name:	pyrI HAMAP-Rule MF_00002
Ordered Locus Names:	STMMW_44041 EMBL CBG27414.1

Organism

Salmonella typhimurium (strain D23580) [Complete proteome] [HAMAP] EMBL CBG27414.1

Taxonomic identifier

568708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella typhimurium

Protein attributes

Sequence length	153 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in allosteric regulation of aspartate carbamoyltransferase By similarity. HAMAP-Rule MF_00002
Cofactor	Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00002
Subunit structure	Contains catalytic and regulatory chains By similarity. HAMAP-Rule MF_00002
Sequence similarities	Belongs to the PyrI family. HAMAP-Rule MF_00002

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis HAMAP-Rule MF_00002
Ligand	Metal-binding HAMAP-Rule MF_00002 Zinc HAMAP-Rule MF_00002
Molecular function	Transferase EMBL CBG27414.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	'de novo' pyrimidine nucleobase biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	aspartate carbamoyltransferase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	109	1	Zinc By similarity HAMAP-Rule MF_00002
	Metal binding	114	1	Zinc By similarity HAMAP-Rule MF_00002
	Metal binding	138	1	Zinc By similarity HAMAP-Rule MF_00002
	Metal binding	141	1	Zinc By similarity HAMAP-Rule MF_00002

Sequences

	Sequence		Length	Mass (Da)
	C9XE68 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 5C5730A07D45FD6F	FASTA	153	17,087
	10 20 30 40 50 60 MTHDNKLQVE AIKCGTVIDH IPAQVGFKLL SLFKLTETDQ RITIGLNLPS GEMGRKDLIK 70 80 90 100 110 120 IENTFLTEEQ VNQLALYAPQ ATVNRIDNYD VVGKSRPSLP ERINNVLVCP NSNCISHAEP 130 140 150 VSSSFAVKKR ANDIALKCKY CEKEFSHYVV LAN

References

[1]

"Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype." Kingsley R.A., Msefula C.L., Thomson N.R., Kariuki S., Holt K.E., Gordon M.A., Harris D., Clarke L., Whitehead S., Sangal V., Marsh K., Achtman M., Molyneux M.E., Cormican M., Parkhill J., Maclennan C.A., Heyderman R.S., Dougan G. Genome Res. 19:2279-2287(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D23580 EMBL CBG27414.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN424405 Genomic DNA. Translation: CBG27414.1.
RefSeq	YP_005235400.1. NC_016854.1.
3D structure databases
ProteinModelPortal	C9XE68.
SMR	C9XE68. Positions 1-153.
ModBase	Search...
Proteomic databases
PRIDE	C9XE68.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBG27414; CBG27414; STMMW_44041.
GeneID	11759420.
KEGG	sev:STMMW_44041.
PATRIC	36730695. VBISalEnt111430_4709.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000113530.
KO	K00610.
Family and domain databases
Gene3D	2.30.30.20. 1 hit. 3.30.70.140. 1 hit.
HAMAP	MF_00002. Asp_carb_tr_reg.
InterPro	IPR020545. Asp_carbamoyltransf_reg_N. IPR002801. Asp_carbamoylTrfase_reg. IPR020542. Asp_carbamoyltrfase_reg_C. [Graphical view]
Pfam	PF01948. PyrI. 1 hit. PF02748. PyrI_C. 1 hit. [Graphical view]
ProDom	PD006194. Asp_carbamoylTrfase_reg. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54893. Asp_carbamoylTrfase_reg. 1 hit. SSF57825. Asp_transf_reg_C. 1 hit.
TIGRFAMs	TIGR00240. ATCase_reg. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C9XE68_SALTD

Accession

Primary (citable) accession number: C9XE68

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)