Skip Header

Contribute Send feedback
Read comments (?) or add your own

C9X9R4 (C9X9R4_SALTD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acetolactate synthase RuleBase RU003591
EC=2.2.1.6 RuleBase RU003591
Gene names
Ordered Locus Names:STMMW_38761 EMBL CBG26889.1
OrganismSalmonella typhimurium (strain D23580) [Complete proteome] [HAMAP] EMBL CBG26889.1
Taxonomic identifier568708 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 pyruvate = 2-acetolactate + CO2.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Binds 1 thiamine pyrophosphate per subunit By similarity.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.

Sequence similarities

Belongs to the TPP enzyme family. RuleBase RU003702

Sequences

Sequence LengthMass (Da)Tools
C9X9R4 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 6587AAE9E6E2BE04

FASTA54859,224
        10         20         30         40         50         60 
MNGAQWVVHA LRAQGVKTVF GYPGGAIMPV YDALYDGGVE HLLCRHEQGA AMAAIGYARS 

        70         80         90        100        110        120 
TGKTGVCIAT SGPGATNLIT GLADALLDSV PVVAITGQVS APFIGTDAFQ EVDVLGLSLA 

       130        140        150        160        170        180 
CTKHSFLVQS LEELPRIMAE AFEVANAGRP GPVLVDIPKD IQLASGELEP WFTTVANEAT 

       190        200        210        220        230        240 
FPQADVEQAR QMLEQAKKPM LYVGGGVGMA QAVPALRKFI AVTQMPVTCT LKGLGAVEAD 

       250        260        270        280        290        300 
YPYYLGMLGM HGTKAANFAV QECDLLIAVG ARFDDRVTGK LNTFAPNASV IHMDIDPAEM 

       310        320        330        340        350        360 
NKLRQAHVAL QGDLNSLLPA LQQPLKIDAW RQSCAELRAE HAWRYDHPGE TIYAPLLLKQ 

       370        380        390        400        410        420 
LSERKPADSV VTTDVGQHQM WSAQHMTYTR PENFITSSGL GTMGFGLPAA VGAQVARPND 

       430        440        450        460        470        480 
TVICISGDGS FMMNVQELGT VKRKQLPLKI VLLDNQRLGM VRQWQQLFFQ ERYSETTLTD 

       490        500        510        520        530        540 
NPDFLMLASA FGIPGQHITR KDQVEAALDT MLASEGPYLL HVSIDELENV WPLVPPGASN 


SEMLEKLS

« Hide

References

[1]"Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype."
Kingsley R.A., Msefula C.L., Thomson N.R., Kariuki S., Holt K.E., Gordon M.A., Harris D., Clarke L., Whitehead S., Sangal V., Marsh K., Achtman M., Molyneux M.E., Cormican M., Parkhill J., Maclennan C.A., Heyderman R.S., Dougan G.
Genome Res. 19:2279-2287(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: D23580 EMBL CBG26889.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FN424405 Genomic DNA. Translation: CBG26889.1.
RefSeqYP_005234884.1. NC_016854.1.

3D structure databases

ProteinModelPortalC9X9R4.
ModBaseSearch...

Proteomic databases

PRIDEC9X9R4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBG26889; CBG26889; STMMW_38761.
GeneID11762907.
KEGGsev:STMMW_38761.
PATRIC36729507. VBISalEnt111430_4140.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000258448.
KOK01652.

Enzyme and pathway databases

UniPathwayUPA00047; UER00055.
UPA00049; UER00059.

Family and domain databases

InterProIPR012846. Acetolactate_synth_lsu.
IPR012000. Thiamin_PyroP_enz_cen_dom.
IPR012001. Thiamin_PyroP_enz_TPP-bd_dom.
IPR000399. TPP-bd_CS.
IPR011766. TPP_enzyme-bd_C.
[Graphical view]
PANTHERPTHR18968:SF13. PTHR18968:SF13. 1 hit.
PfamPF02775. TPP_enzyme_C. 1 hit.
PF00205. TPP_enzyme_M. 1 hit.
PF02776. TPP_enzyme_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00118. acolac_lg. 1 hit.
PROSITEPS00187. TPP_ENZYMES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC9X9R4_SALTD
AccessionPrimary (citable) accession number: C9X9R4
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info