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C9X080 (C9X080_NEIM8) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidine--tRNA ligase HAMAP-Rule MF_00127
EC=6.1.1.21 HAMAP-Rule MF_00127
Alternative name(s):
Histidyl-tRNA synthetase HAMAP-Rule MF_00127
Gene names
Name:hisS HAMAP-Rule MF_00127 EMBL CAX50373.1
Ordered Locus Names:NMV_1554
OrganismNeisseria meningitidis serogroup C (strain 8013) [Complete proteome] [HAMAP]
Taxonomic identifier604162 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria ›

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). HAMAP-Rule MF_00127 SAAS SAAS015807

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00127

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00127.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00127 RuleBase RU003746

Sequences

Sequence LengthMass (Da)Tools
C9X080 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: B23B0B50811121C5

FASTA43148,593
        10         20         30         40         50         60 
MAQKIQSVKG MNDLLPVEQK DFKLTAAFWQ AFEDTVGRWT RAYGYQQIRT PIVEQTGLFV 

        70         80         90        100        110        120 
RSIGEETDVV GKEMYTFSDS NDSLSLSLRP EGTASCLRAV VEHNLLYNSP QKLWYMGPMF 

       130        140        150        160        170        180 
RRERPQKGRY RQFHQVGIEA LGFEGPDIDA EIITMSADLW EKLSIREYLT LEINSLGNRE 

       190        200        210        220        230        240 
ERAAHRAALV EYLTRYEDKL DEDSKRRLKT NPLRVLDTKN PDLQEICNAA PRLVDYLGEA 

       250        260        270        280        290        300 
SQNHYARFKA MLDGLGIQYI ENPRLVRGLD YYNQTVFEWT TDKLGAQATV CGGGRYDGLI 

       310        320        330        340        350        360 
EELGGKPAPS IGFAMGIERL LLLVSEYGSL EVNAAPDVYA MHQGERADLQ VMKYAQALRA 

       370        380        390        400        410        420 
QGFNVMQHSG YQSLKAQMKK ADNSGARFAL IVAQDELANG TVTLKDMNGA HGQQTVAAED 

       430 
LTHTLQQWKN A

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References

[1]"NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis."
Rusniok C., Vallenet D., Floquet S., Ewles H., Mouze-Soulama C., Brown D., Lajus A., Buchrieser C., Medigue C., Glaser P., Pelicic V.
Genome Biol. 10:R110.1-R110.13(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 8013.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM999788 Genomic DNA. Translation: CAX50373.1.
RefSeqYP_005878849.1. NC_017501.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAX50373; CAX50373; NMV_1554.
GeneID12395266.
KEGGnmt:NMV_1554.
PATRIC36833758. VBINeiMen144578_1830.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000018072.
KOK01892.
OMACGGGNFK.

Family and domain databases

Gene3D3.40.50.800. 1 hit.
HAMAPMF_00127. His_tRNA_synth.
InterProIPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
[Graphical view]
PANTHERPTHR11476. PTHR11476. 1 hit.
PfamPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
PIRSFPIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMSSF52954. Anticodon_bd. 1 hit.
TIGRFAMsTIGR00442. hisS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC9X080_NEIM8
AccessionPrimary (citable) accession number: C9X080
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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