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Protein

Endochitinase 4

Gene

chi4

Organism
Metarhizium anisopliae (Entomophthora anisopliae)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods). Participates in the infection process and directly acts in the penetration process of the host cuticle (By similarity).By similarity

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei112Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation, Virulence
LigandChitin-binding

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Endochitinase 4 (EC:3.2.1.14)
Alternative name(s):
Chitinase 4
Gene namesi
Name:chi4
OrganismiMetarhizium anisopliae (Entomophthora anisopliae)
Taxonomic identifieri5530 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesClavicipitaceaeMetarhizium

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004298701 – 282Endochitinase 4Add BLAST282

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi265N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliC9WJD0.
SMRiC9WJD0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9WJD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GAKNGVHPPL GWIPIQDARI RQHGYNVISA AFPVILPDGT ALWEDGMDAN
60 70 80 90 100
VKVATPAEMC QAKAAGATMV MSIGGAAAAI DLSSSSVADK FVSTIVPILK
110 120 130 140 150
RYNFDGVDID IEAGLSGSGT FGTLSASQAN LVRIIDGILA QMPSNFGLTM
160 170 180 190 200
APETAYVTGG SVTYGSIWGA YLPIIKKYAD NGRLWWLNMQ YYNGAMYGCS
210 220 230 240 250
GDSYEAGTVK GFVAQTDCLD KGLVIQGTTI RVPYDKQVPG LPAQSGAGGG
260 270 280
YMSPSLVGQA WDHYNGSLKG LMTWSINWDG SK
Length:282
Mass (Da):29,690
Last modified:November 24, 2009 - v1
Checksum:i0E7DEFA8AB0FFF89
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei2821

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ609317 Genomic DNA. Translation: ACU30521.1.

Similar proteinsi

Entry informationi

Entry nameiCHI4_METAN
AccessioniPrimary (citable) accession number: C9WJD0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 9, 2014
Last sequence update: November 24, 2009
Last modified: May 10, 2017
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families