C9UE09 (C9UE09_BRUAO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenine phosphoribosyltransferase HAMAP MF_00004
Short name=APRT HAMAP MF_00004
EC=2.4.2.7 HAMAP MF_00004

Gene names

Name:	apt HAMAP MF_00004
ORF Names:	BABG_02923 EMBL EEX55737.1

Organism

Brucella abortus bv. 4 str. 292 EMBL EEX55737.1

Taxonomic identifier

520452 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	181 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis By similarity. HAMAP MF_00004
Catalytic activity	AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00004
Pathway	Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. HAMAP MF_00004
Subunit structure	Homodimer By similarity. HAMAP MF_00004
Subcellular location	Cytoplasm By similarity HAMAP MF_00004.
Sequence similarities	Belongs to the purine/pyrimidine phosphoribosyltransferase family. HAMAP MF_00004

Ontologies

Keywords
Biological process	Purine salvage HAMAP MF_00004
Cellular component	Cytoplasm HAMAP MF_00004
Molecular function	Glycosyltransferase HAMAP MF_00004 EMBL EEX55737.1 Transferase
Gene Ontology (GO)
Biological process	adenine salvage Inferred from electronic annotation. Source: HAMAP purine ribonucleoside salvage Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	adenine phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C9UE09 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 128ABF9D88C2A953	FASTA	181	19,614
	10 20 30 40 50 60 MESGFKVTLK DAIRTIPDYP KPGVQFRDVT TLMGNAQAFR RAVDELVYPY AGNRIDKVAG 70 80 90 100 110 120 IEARGFILGG AIAHQLSAGF VPIRKKGKLP RDTVRIAYSL EYGVDEMEMH RDAIEKGERV 130 140 150 160 170 180 VLVDDLIATG GTAEAAAKLL LQMGAEIVAA CFIIDLPDLG GRKKLEALGL PVRTLVAFEG D

References

[1]

"The Genome Sequence of Brucella abortus bv. 4 str. 292." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 292 EMBL EEX55737.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS999875 Genomic DNA. Translation: EEX55737.1.
3D structure databases
ProteinModelPortal	C9UE09.
SMR	C9UE09. Positions 8-181.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	24181422. VBIBruAbo93713_1286.
Family and domain databases
HAMAP	MF_00004. Aden_phosphoribosyltr. [Tree]
InterPro	IPR005764. Ade_phspho_trans. IPR000836. PRibTrfase. [Graphical view]
Pfam	PF00156. Pribosyltran. 1 hit. [Graphical view]
TIGRFAMs	TIGR01090. Apt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C9UE09_BRUAO

Accession

Primary (citable) accession number: C9UE09

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	December 14, 2011
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)