Skip Header

Contribute Send feedback
Read comments (?) or add your own

C9U098 (C9U098_9RHIZ) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ferrochelatase RuleBase RU000607 HAMAP MF_00323

EC=4.99.1.1 RuleBase RU000607 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323 EMBL AEK55538.1
ORF Names:BAHG_02045 EMBL EEY01669.1, BPI_II78 EMBL AEK55538.1
OrganismBrucella pinnipedialis B2/94 EMBL EEY01669.1
Taxonomic identifier520461 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. SAAS SAAS001015 RuleBase RU000607 HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. SAAS SAAS001015 RuleBase RU000607 HAMAP MF_00323

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. SAAS SAAS001015 RuleBase RU000607 HAMAP MF_00323

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. RuleBase RU004185 HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
C9U098 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 5FE6C0F0EA435D32

FASTA35240,057
        10         20         30         40         50         60 
MSGTDKVRVN VSQTAQTPLH TSAKLPKVGV LLVNLGTPDG TSYGPMRRYL AEFLSDRRVI 

        70         80         90        100        110        120 
EWSRLIWYPI LYGIVLNTRP RRSGRLYDRI WNHENNESPL RTYTRAQGEK LAKALSDQPN 

       130        140        150        160        170        180 
VVVDWAMRYG QPSIESITDR LLQQGCERIV IFPLYPQYSA TTTATVNDKF FEALMKKRFM 

       190        200        210        220        230        240 
PAIRTVPSYE AEPVYIDALA RSVEKHLATL SFKPEVILTS YHGIPKSYSD KGDPYRQQCL 

       250        260        270        280        290        300 
ETTRLLRERL GLGEDEMRAT FQSRFGPEEW LQPYTDETVK ELAKNGVKSV AVLNPGFVAD 

       310        320        330        340        350 
CLETVDEIGN EAAEEFLENG GENFSHIPCL NDSEEGMKVI ETLVRRELLG WV 

« Hide

References

[1]"The genome sequence of Brucella pinnipedialis B2/94 sheds light on the evolutionary history of the genus Brucella."
Audic S., Lescot M., Claverie J.M., Cloeckaert A., Zygmunt M.S.
BMC Evol. Biol. 11:200-200(2011) [PubMed: 21745361] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL AEK55538.1.
[2]"The Genome Sequence of Brucella pinnipedialis B2/94."
The Broad Institute Genome Sequencing Platform
Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. expand/collapse author list , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL EEY01669.1.
[3]Zygmunt M., Clockaert A.
Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL AEK55538.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002079 Genomic DNA. Translation: AEK55538.1.
DS999851 Genomic DNA. Translation: EEY01669.1.
RefSeqYP_004757306.1. NC_015858.1.

3D structure databases

ProteinModelPortalC9U098.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10995293.
PATRIC24254719. VBIBruPin17457_2948.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC9U098_9RHIZ
AccessionPrimary (citable) accession number: C9U098
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: January 25, 2012
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)