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C9TW13 (C9TW13_9RHIZ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818
EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818 EMBL AEK54498.1
ORF Names:BAHG_01465 EMBL EEY00536.1, BPI_I1231 EMBL AEK54498.1
OrganismBrucella pinnipedialis B2/94 EMBL EEY00536.1
Taxonomic identifier520461 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length155 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. SAAS SAAS016856 HAMAP MF_00818

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. SAAS SAAS016856 HAMAP MF_00818

Pathway

tRNA modification; tRNA-queuosine biosynthesis. SAAS SAAS016856 HAMAP MF_00818

Subcellular location

Cytoplasm By similarity SAAS SAAS016856 HAMAP MF_00818.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
C9TW13 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: EB93CD3CC760ADE1

FASTA15517,416
        10         20         30         40         50         60 
MSENTIYSGL KQLGSHTDIP LTPEEAVLER VANPQEGTPY CVRFTAPEFT SLCPMTGQPD 

        70         80         90        100        110        120 
FAHLVIDYVP GKWLVESKSL KLFLFSFRNH GAFHEDCTVT IGKRLVDLLE PEWLRIGGYW 

       130        140        150 
YPRGGIPIDV FYQTGAAPLN VWIPEQGVAN YRGRG

« Hide

References

[1]"The genome sequence of Brucella pinnipedialis B2/94 sheds light on the evolutionary history of the genus Brucella."
Audic S., Lescot M., Claverie J.M., Cloeckaert A., Zygmunt M.S.
BMC Evol. Biol. 11:200-200(2011) [PubMed: 21745361] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL AEK54498.1.
[2]"The Genome Sequence of Brucella pinnipedialis B2/94."
The Broad Institute Genome Sequencing Platform
Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. expand/collapse author list , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL EEY00536.1.
[3]Zygmunt M., Clockaert A.
Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL AEK54498.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002078 Genomic DNA. Translation: AEK54498.1.
DS999848 Genomic DNA. Translation: EEY00536.1.
RefSeqYP_004756266.1. NC_015857.1.

3D structure databases

ProteinModelPortalC9TW13.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10997708.
PATRIC24252278. VBIBruPin17457_1264.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC9TW13_9RHIZ
AccessionPrimary (citable) accession number: C9TW13
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: December 14, 2011
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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