C9TUZ6 (C9TUZ6_BRUPB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP-Rule MF_00123
EC=6.1.1.19 HAMAP-Rule MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP-Rule MF_00123

Gene names

Name:	argS HAMAP-Rule MF_00123 EMBL AEK54201.1
ORF Names:	BAHG_01176 EMBL EEY00247.1, BPI_I913 EMBL AEK54201.1

Organism

Brucella pinnipedialis (strain NCTC 12890 / BCCN 94-73 / B2/94) [Complete proteome] [HAMAP] EMBL EEY00247.1

Taxonomic identifier

520461 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella pinnipedialis

Protein attributes

Sequence length	585 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00123
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489 HAMAP-Rule MF_00123

Ontologies

Keywords
Biological process	Protein biosynthesis RuleBase RU003489 HAMAP-Rule MF_00123
Cellular component	Cytoplasm HAMAP-Rule MF_00123
Ligand	ATP-binding RuleBase RU003489 HAMAP-Rule MF_00123 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase RuleBase RU003489 HAMAP-Rule MF_00123 EMBL EEY00247.1 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Motif	131 – 141	11	"HIGH" region By similarity HAMAP-Rule MF_00123

Sequences

	Sequence		Length	Mass (Da)
	C9TUZ6 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: D9F99D72766C2B6B	FASTA	585	65,124
	10 20 30 40 50 60 MNIFADFDAR IKKTLQDIDL KPKDGGELDL SRIGVEPPRD ASHGDIATNA AMVLSKAVGQ 70 80 90 100 110 120 NPRELAARIA EALKADEDVE SVDVAGPGFI NLRLKASYWQ RELLVMLNEG TDFGRSRLGA 130 140 150 160 170 180 GKKVNVEYVS ANPTGPMHVG HCRGAVVGDV LANLLKFAGY DVVKEYYIND AGAQIDVLAR 190 200 210 220 230 240 SVMLRYREAL GESIGEIPAG LYPGDYLVRV GQELAGEFGT KLLEMPEAEA LAIVKDRTID 250 260 270 280 290 300 AMMAMIRADL DALNVHHDVF YSERKLHVDH ARAIRNAIND LTLKGHVYKG KLPPPKGQLP 310 320 330 340 350 360 EDWEDREQTL FRSTEVGDDI DRPLMKSDGS FTYFAGDVAY FKDKYDRGFN EMIYVLGADH 370 380 390 400 410 420 GGYVKRLEAV ARAVSDGKAK LTVLLCQLVK LFRNGEPVRM SKRAGEFITL RDVVDEVGRD 430 440 450 460 470 480 PVRFMMLYRK NDAPLDFDFA KVTEQSKDNP VFYVQYASAR CHSVFRQAAD QLGLVDLDRV 490 500 510 520 530 540 AMGSHFEKLT DESEIALVRK LAEYPRLIES AAIHQEPHRL AFYLYDLASS FHSQWNRGTE 550 560 570 580 NPDLRFIKVN DPDLSLARLG LVQVVSDVLT SGLTIIGADA PTEMR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Genome Sequence of Brucella pinnipedialis B2/94." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: B2/94 EMBL EEY00247.1.
[2]	Zygmunt M., Clockaert A. Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: B2/94 EMBL AEK54201.1.
[3]	"The genome sequence of Brucella pinnipedialis B2/94 sheds light on the evolutionary history of the genus Brucella." Audic S., Lescot M., Claverie J.M., Cloeckaert A., Zygmunt M.S. BMC Evol. Biol. 11:200-200(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B2/94 EMBL AEK54201.1 and NCTC 12890 / BCCN 94-73 / B2/94.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002078 Genomic DNA. Translation: AEK54201.1. DS999848 Genomic DNA. Translation: EEY00247.1.
RefSeq	YP_004755969.1. NC_015857.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEK54201; AEK54201; BPI_I913. EEY00247; EEY00247; BAHG_01176.
GeneID	10997390.
KEGG	bpp:BPI_I913.
PATRIC	24251657. VBIBruPin17457_0931.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01887.
Enzyme and pathway databases
BioCyc	BPIN520461:GJF0-910-MONOMER.
Family and domain databases
Gene3D	3.30.1360.70. 1 hit. 3.40.50.620. 1 hit.
HAMAP	MF_00123. Arg_tRNA_synth.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
PANTHER	PTHR11956. PTHR11956. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C9TUZ6_BRUPB

Accession

Primary (citable) accession number: C9TUZ6

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)