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Protein
Submitted name:

1-deoxy-D-xylulose-5-phosphate synthase

Gene

dxs

Organism
Brucella pinnipedialis (strain NCTC 12890 / BCCN 94-73 / B2/94)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 1-deoxy-D-xylulose-5-phosphate synthase activity Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. thiamine pyrophosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. 1-deoxy-D-xylulose 5-phosphate biosynthetic process Source: UniProtKB-UniPathway
  2. terpenoid biosynthetic process Source: UniProtKB-HAMAP
  3. thiamine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Enzyme and pathway databases

BioCyciBPIN520461:GJF0-465-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
1-deoxy-D-xylulose-5-phosphate synthaseImported
Gene namesi
Name:dxsImported
Ordered Locus Names:BPI_I466Imported
OrganismiBrucella pinnipedialis (strain NCTC 12890 / BCCN 94-73 / B2/94)Imported
Taxonomic identifieri520461 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000010095 Componenti: Chromosome 1

Family & Domainsi

Phylogenomic databases

KOiK01662.

Family and domain databases

Gene3Di3.40.50.920. 1 hit.
3.40.50.970. 3 hits.
HAMAPiMF_00315. DXP_synth.
InterProiIPR005477. Dxylulose-5-P_synthase.
IPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
PfamiPF13292. DXP_synthase_N. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 3 hits.
SSF52922. SSF52922. 1 hit.
TIGRFAMsiTIGR00204. dxs. 1 hit.
PROSITEiPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9TTT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRPSTPLLD KAPTPDRLRA LPEQDLPQLA EELRTELIDA VSTTGGHLGA
60 70 80 90 100
GLGVVELTVA LHHVFNTPYD RIIWDVGHQA YPHKILTGRR DRIRTLRQAG
110 120 130 140 150
GLSGFTKRAE SEYDPFGAAH SSTSISAGLG MAVASELSGE KRNVIAVIGD
160 170 180 190 200
GSMSAGMAYE AMNNAGALDA RLIVILNDND MSIAPPTGAM SAYLARLVSG
210 220 230 240 250
RTYRSVREAA KQVAQKLPKF LQDKARKSEE YARAFFTGGT LFEELGFYYV
260 270 280 290 300
GPIDGHNLDH LLPVLKNVRD TQKGPVLIHV VTQKGKGYAP AEAAADKYHG
310 320 330 340 350
VNEFDVITGK QAKPPANAPS YTKIFGTSLI EEARHDDKIV AVTAAMPTGT
360 370 380 390 400
GLDLFGEAFP KRVFDVGIAE QHAVTFAAGL ASEGYKPFCA IYSTFLQRGY
410 420 430 440 450
DQVVHDVSIQ NLPVRFPIDR AGLVGADGPT HAGSFDTGFL AALPGFVVMA
460 470 480 490 500
ASDEAELRHM VRTAAEYDEG PISFRYPRGD GVGVDLPERG SVLEIGKGRI
510 520 530 540 550
VREGTKVALL SFGTRLQECL AAAEELGAAG LSTTVADARF AKPLDHDLIR
560 570 580 590 600
RLAREHEVLV MVEEGAVGGF GSHVLQFLAT DGLLDRGLKV RALTLPDIYQ
610 620 630 640
DHGKPDAMYA EAGLDRTGIV RTVFAALHRD ELGHEALPTP FRA
Length:643
Mass (Da):69,153
Last modified:November 23, 2009 - v1
Checksum:i4948F8DD11A59F65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002078 Genomic DNA. Translation: AEK53773.1.
RefSeqiYP_004755541.1. NC_015857.1.

Genome annotation databases

EnsemblBacteriaiAEK53773; AEK53773; BPI_I466.
EEX99831; EEX99831; BAHG_00761.
GeneIDi10996945.
KEGGibpp:BPI_I466.
PATRICi24250790. VBIBruPin17457_0401.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002078 Genomic DNA. Translation: AEK53773.1.
RefSeqiYP_004755541.1. NC_015857.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEK53773; AEK53773; BPI_I466.
EEX99831; EEX99831; BAHG_00761.
GeneIDi10996945.
KEGGibpp:BPI_I466.
PATRICi24250790. VBIBruPin17457_0401.

Phylogenomic databases

KOiK01662.

Enzyme and pathway databases

BioCyciBPIN520461:GJF0-465-MONOMER.

Family and domain databases

Gene3Di3.40.50.920. 1 hit.
3.40.50.970. 3 hits.
HAMAPiMF_00315. DXP_synth.
InterProiIPR005477. Dxylulose-5-P_synthase.
IPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
PfamiPF13292. DXP_synthase_N. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 3 hits.
SSF52922. SSF52922. 1 hit.
TIGRFAMsiTIGR00204. dxs. 1 hit.
PROSITEiPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Brucella pinnipedialis B2/94 sheds light on the evolutionary history of the genus Brucella."
    Audic S., Lescot M., Claverie J.M., Cloeckaert A., Zygmunt M.S.
    BMC Evol. Biol. 11:200-200(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 12890 / BCCN 94-73 / B2/94Imported.

Entry informationi

Entry nameiC9TTT1_BRUPB
AccessioniPrimary (citable) accession number: C9TTT1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2009
Last sequence update: November 23, 2009
Last modified: March 31, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.