C9TTC2 (C9TTC2_BRUPB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Urease subunit gamma RuleBase RU003850 HAMAP-Rule MF_00739
EC=3.5.1.5 RuleBase RU003850 HAMAP-Rule MF_00739

Alternative name(s):
Urea amidohydrolase subunit gamma HAMAP-Rule MF_00739

Gene names

Name:	ureA-1 EMBL AEK53610.1
Synonyms:	ureA HAMAP-Rule MF_00739
ORF Names:	BAHG_00602 EMBL EEX99672.1, BPI_I302 EMBL AEK53610.1

Organism

Brucella pinnipedialis (strain NCTC 12890 / BCCN 94-73 / B2/94) [Complete proteome] [HAMAP] EMBL EEX99672.1

Taxonomic identifier

520461 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella pinnipedialis

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. SAAS SAAS012010 RuleBase RU003850 HAMAP-Rule MF_00739
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. SAAS SAAS012010 HAMAP-Rule MF_00739
Subunit structure	Heterotrimer of ureA (gamma), ureB (beta) and ureC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity. HAMAP-Rule MF_00739
Subcellular location	Cytoplasm By similarity SAAS SAAS012010 RuleBase RU003850 HAMAP-Rule MF_00739.
Sequence similarities	Belongs to the urease gamma subunit family. RuleBase RU003850 HAMAP-Rule MF_00739

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS012010 HAMAP-Rule MF_00739
Molecular function	Hydrolase SAAS SAAS012010 RuleBase RU003850 HAMAP-Rule MF_00739 EMBL AEK53610.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	urea catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nickel cation binding Inferred from electronic annotation. Source: InterPro urease activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C9TTC2 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 98BAAAE973961FE1	FASTA	100	11,103
	10 20 30 40 50 60 MNLTPREKDK LLIAMAAMVA RRRLERGVKL NHPEAIALVS DFVVEGARDG RTVAELMEAG 70 80 90 100 AHVITREQVM DGVAEMIRDI QVEATFPDGT KLVTVHEPIR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Genome Sequence of Brucella pinnipedialis B2/94." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: B2/94 EMBL EEX99672.1.
[2]	Zygmunt M., Clockaert A. Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: B2/94 EMBL AEK53610.1.
[3]	"The genome sequence of Brucella pinnipedialis B2/94 sheds light on the evolutionary history of the genus Brucella." Audic S., Lescot M., Claverie J.M., Cloeckaert A., Zygmunt M.S. BMC Evol. Biol. 11:200-200(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B2/94 EMBL AEK53610.1 and NCTC 12890 / BCCN 94-73 / B2/94.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002078 Genomic DNA. Translation: AEK53610.1. DS999848 Genomic DNA. Translation: EEX99672.1.
RefSeq	YP_004755378.1. NC_015857.1.
3D structure databases
SMR	C9TTC2. Positions 1-99.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEK53610; AEK53610; BPI_I302. EEX99672; EEX99672; BAHG_00602.
GeneID	10996781.
KEGG	bpp:BPI_I302.
PATRIC	24250458. VBIBruPin17457_0236.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01430.
Enzyme and pathway databases
BioCyc	BPIN520461:GJF0-301-MONOMER.
UniPathway	UPA00258; UER00370.
Family and domain databases
Gene3D	3.30.280.10. 1 hit.
HAMAP	MF_00739. Urease_gamma.
InterPro	IPR002026. Urease_gamma/gamma-beta_su. IPR012010. Urease_gamma_su. [Graphical view]
Pfam	PF00547. Urease_gamma. 1 hit. [Graphical view]
PIRSF	PIRSF001223. Urease_gamma. 1 hit.
ProDom	PD002319. Urease_gamma_reg. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54111. Urease_gamma_reg. 1 hit.
TIGRFAMs	TIGR00193. urease_gam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C9TTC2_BRUPB

Accession

Primary (citable) accession number: C9TTC2

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)