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C9TST5 (C9TST5_9RHIZ) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456 EMBL AEK55135.1
ORF Names:BAHG_03249 EMBL EEX99055.1, BPI_I1900 EMBL AEK55135.1
OrganismBrucella pinnipedialis B2/94 EMBL EEX99055.1
Taxonomic identifier520461 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. SAAS SAAS011529 HAMAP MF_00456

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. SAAS SAAS011529 HAMAP MF_00456

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. SAAS SAAS011529 HAMAP MF_00456

Subcellular location

Cytoplasm By similarity SAAS SAAS011529 HAMAP MF_00456.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. SAAS SAAS011529 HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
C9TST5 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: D4AA35B35182226A

FASTA37839,874
        10         20         30         40         50         60 
MLKKLKDYRR IVVKIGSALL VDRATGLKRE WLESLGQDIA ALQHAGVEVL VVSSGAIALG 

        70         80         90        100        110        120 
RTVLGLPKKA LKLEESQAAA AAGQIALAKA YADVLGGHGI KSGQILVTLS DTEERRRYLN 

       130        140        150        160        170        180 
ARATIETLLK LKAVPIINEN DTVATTEIRY GDNDRLAARV ATMMGADLLI LLSDIDGLYT 

       190        200        210        220        230        240 
APPHKNPDAQ FLPFVETITP QIEAMAGAAA SELSRGGMKT KLDAGKIANA AGTAMIITSG 

       250        260        270        280        290        300 
TRFGPLSAID RGERATLFEA AHAPVNAWKT WISGNLEPAG RLTVDAGAVK ALKSGKSLLP 

       310        320        330        340        350        360 
AGVKEVDGDF ERGDTVAVMN EDGREIARGL IAYDAADARK VAGHKSDEIS AILGYDARAA 

       370 
MIHRNDLVVR AASDAKAA

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References

[1]"The genome sequence of Brucella pinnipedialis B2/94 sheds light on the evolutionary history of the genus Brucella."
Audic S., Lescot M., Claverie J.M., Cloeckaert A., Zygmunt M.S.
BMC Evol. Biol. 11:200-200(2011) [PubMed: 21745361] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL AEK55135.1.
[2]"The Genome Sequence of Brucella pinnipedialis B2/94."
The Broad Institute Genome Sequencing Platform
Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. expand/collapse author list , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL EEX99055.1.
[3]Zygmunt M., Clockaert A.
Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: B2/94 EMBL AEK55135.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002078 Genomic DNA. Translation: AEK55135.1.
DS999845 Genomic DNA. Translation: EEX99055.1.
RefSeqYP_004756903.1. NC_015857.1.

3D structure databases

ProteinModelPortalC9TST5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10998377.
PATRIC24249150. VBIBruPin17457_0215.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC9TST5_9RHIZ
AccessionPrimary (citable) accession number: C9TST5
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: January 25, 2012
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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