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C9SJ15 (DAPB_VERA1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length875 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activity

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein By similarity. Note: Lysosome-like vacuoles By similarity.

Sequence similarities

Belongs to the peptidase S9B family.

Ontologies

Keywords
   Cellular componentMembrane
Vacuole
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   Molecular functionAminopeptidase
Hydrolase
Protease
Serine protease
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

vacuolar membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionaminopeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

serine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 875875Probable dipeptidyl-aminopeptidase B
PRO_0000412168

Regions

Topological domain1 – 9898Cytoplasmic Potential
Transmembrane99 – 11921Helical; Signal-anchor for type II membrane protein; Potential
Topological domain120 – 875756Vacuolar Potential

Sites

Active site7261Charge relay system By similarity
Active site8031Charge relay system By similarity
Active site8361Charge relay system By similarity

Amino acid modifications

Glycosylation3541N-linked (GlcNAc...) Potential
Glycosylation5671N-linked (GlcNAc...) Potential
Glycosylation7851N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
C9SJ15 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 6ED2051D22DBFEB2

FASTA87598,704
        10         20         30         40         50         60 
MSEPKPIQDT LDRRHSRESS ISSASTTSLV FDRLAEESEK NHDASSRPHP SAARHAYTDD 

        70         80         90        100        110        120 
NSDAIKESDI NDPETGPFLG ASSETTPPRK GVDRKLKKVL LIVGGFFVAA WIVSLVVFLT 

       130        140        150        160        170        180 
NKSYKHGSQI DHDPAATNRK SGKRVTLDQV QSGFWRPTSH TFSWIPGPDG EDGLLLEQEA 

       190        200        210        220        230        240 
RGKHFLVVED VRSQGSADGE AHPDAAESRT LIKDPWFYWG DQQHSILQTW PSKNQKKVLV 

       250        260        270        280        290        300 
ATQKQRNWRH SFTALYWVFD VESQSAEPLD PAHPEERVQL ATWNAQSDAI VFTRSNNLFL 

       310        320        330        340        350        360 
RKLADDKVTP ITTDGGPEYF YGIPDWVYEE EVFSGNSATW WSADGKHVAF LRTNETEVPE 

       370        380        390        400        410        420 
YPIQYFVSRP SGAEPEVGEE NYPEVRQIKY PKVGSPNPVV DLLFYDVEKG DVFTVDIDGD 

       430        440        450        460        470        480 
FPEKDKLINF VMWADGNVLV KTTNRVSDVL QVNLIDIVAR TGKTVQHVDV AKIDGGWFEI 

       490        500        510        520        530        540 
SHVMYIPADP KNGRPHDGYV DTVIHNDGDH LAYFTPMDNP KPVYITEGPG WEVDGSASAV 

       550        560        570        580        590        600 
DLKNNLVYFR STKESSIQRH IYSVHLNGTD MKPFTDTTHE SYYDVSFSSG AGFGLLSYQG 

       610        620        630        640        650        660 
PKVPWQKVVS TPSNPKSYER IIEENKDLTQ QAKKHELPVL EYGTIKVDDV ELNYVERRPP 

       670        680        690        700        710        720 
HFDKNKKYPV LFQQYSGPGS QTVTKKFAVD FQSSDGGRRT TRSPRRATGR PSATSTPTAF 

       730        740        750        760        770        780 
AIWGWSYGGF ATLKTLETDA GRTFRYGMAV APVTDWRFYD SIYTERYMRT PDLNRNGYQQ 

       790        800        810        820        830        840 
TAISNTTALG ANERFLVMHG VADDNVHMQN TLTLLDELDL AGVENYDVHV FPDSDHSIYF 

       850        860        870 
HNANRIVYDK LSNWLINAFN GEWVKVNDAK PKIES 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS985218 Genomic DNA. Translation: EEY18938.1.
RefSeqXP_003005441.1. XM_003005395.1.

3D structure databases

ProteinModelPortalC9SJ15.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9532123.
KEGGval:VDBG_05047.

Phylogenomic databases

KOK01282.
OrthoDBEOG72VHFG.

Family and domain databases

Gene3D2.140.10.30. 1 hit.
InterProIPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPB_VERA1
AccessionPrimary (citable) accession number: C9SJ15
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: November 24, 2009
Last modified: April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries