Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C9S0R2 (BGAL_GEOSY) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-galactosidase BgaB

Short name=Beta-gal
EC=3.2.1.23
Alternative name(s):
Beta-galactosidase I
Lactase
Gene names
Name:bgaB
Ordered Locus Names:GYMC61_0530
OrganismGeobacillus sp. (strain Y412MC61) [Complete proteome] [HAMAP]
Taxonomic identifier544556 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length672 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sequence similarities

Belongs to the glycosyl hydrolase 42 family.

Ontologies

Keywords
   LigandMetal-binding
Zinc
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgalactose metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentbeta-galactosidase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 672672Beta-galactosidase BgaB
PRO_0000407689

Regions

Region351 – 3544Substrate binding By similarity

Sites

Active site1481Proton donor By similarity
Active site3031Nucleophile By similarity
Metal binding1131Zinc By similarity
Metal binding1561Zinc By similarity
Metal binding1581Zinc By similarity
Metal binding1611Zinc By similarity
Binding site1091Substrate By similarity
Binding site1471Substrate By similarity
Binding site3111Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
C9S0R2 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 5B4573522E398425

FASTA67278,015
        10         20         30         40         50         60 
MNVLSSICYG GDYNPEQWPE EIWYEDAKLM QKAGVNLVSL GIFSWSKIEP SDGVFDFEWL 

        70         80         90        100        110        120 
DKVIDILYDH GVYINLGTAT ATTPAWFVKK YPDSLPIDES GVIFSFGSRQ HYCPNHPQLI 

       130        140        150        160        170        180 
THIKRLVRAI AERYKNHPAL KMWHVNNEYA CHVSKCFCEN CAVAFRKWLK ERYKTIDELN 

       190        200        210        220        230        240 
ERWGTNFWGQ RYNHWDEINP PRKAPTFINP SQELDYYRFM NDSILKLFLT EKEILRGVTP 

       250        260        270        280        290        300 
DIPVSTNFMG SFKPLNYFQW AQHVDIVTWD SYPDPREGLP IQHAMMNDLM RSLRKGQPFI 

       310        320        330        340        350        360 
LMEQVTSHVN WRDINVPKPP GVMRLWSYAT IARGADGIMF FQWRQSRAGA EKFHGAMVPH 

       370        380        390        400        410        420 
FLNENNRIYR EVTQLGQELK KLDCLVGSRI KAEVAIIFDW ENWWAVELSS KPHNKLRYIP 

       430        440        450        460        470        480 
IVEAYYRELY KRNIAVDFVR PSDDLTKYKV VIAPMLYMVK EGEDENLRQF VANGGTLIVS 

       490        500        510        520        530        540 
FFSGIVDEND RVHLGGYPGP LRDILGIFVE EFVPYPETKV NKIYSNDGEY DCTTWADIIR 

       550        560        570        580        590        600 
LEGAEPLATF KGDWYAGLPA VTRNCYGKGE GIYVGTYPDS NYLGRLLEQV FAKHHINPIL 

       610        620        630        640        650        660 
EVAENVEVQQ RETDEWKYLI IINHNDYEVT LSLPEDKIYQ NMIDGKCFRG GELRIQGVDV 

       670 
AVLREHDEAG KV 

« Hide

References

[1]"Complete sequence of chromosome of Geobacillus sp. Y412MC61."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Brumm P., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y412MC61.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001794 Genomic DNA. Translation: ACX77212.1.
RefSeqYP_003251694.1. NC_013411.1.

3D structure databases

ProteinModelPortalC9S0R2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING544556.GYMC61_0530.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX77212; ACX77212; GYMC61_0530.
GeneID8524336.
KEGGgyc:GYMC61_0530.
PATRIC32162521. VBIGeoSp85804_0561.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1874.
HOGENOMHOG000117811.
KOK12308.
OMAHIWLGGY.
OrthoDBEOG6GTZGG.

Enzyme and pathway databases

BioCycGSP544556:GI3L-565-MONOMER.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFPIRSF001084. B-galactosidase. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBGAL_GEOSY
AccessionPrimary (citable) accession number: C9S0R2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: November 24, 2009
Last modified: June 11, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries