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Protein

Signal peptidase I

Gene

GYMC61_1987

Organism
Geobacillus sp. (strain Y412MC61)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.UniRule annotation

GO - Molecular functioni

  1. serine-type peptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseUniRule annotation

Enzyme and pathway databases

BioCyciGSP544556:GI3L-2080-MONOMER.

Protein family/group databases

MEROPSiS26.018.

Names & Taxonomyi

Protein namesi
Recommended name:
Signal peptidase IUniRule annotation (EC:3.4.21.89UniRule annotation)
Gene namesi
Ordered Locus Names:GYMC61_1987Imported
OrganismiGeobacillus sp. (strain Y412MC61)Imported
Taxonomic identifieri544556 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
ProteomesiUP000008468 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi544556.GYMC61_1987.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S26 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0681.
HOGENOMiHOG000003673.
KOiK03100.
OMAiGKPYEEP.
OrthoDBiEOG622PW8.

Family and domain databases

Gene3Di2.10.109.10. 2 hits.
InterProiIPR000223. Pept_S26A_signal_pept_1.
IPR019758. Pept_S26A_signal_pept_1_CS.
IPR019757. Pept_S26A_signal_pept_1_Lys-AS.
IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
IPR028360. Peptidase_S24/S26_b-rbn.
IPR019759. Peptidase_S24_S26.
IPR015927. Peptidase_S24_S26A/B/C.
[Graphical view]
PANTHERiPTHR12383. PTHR12383. 1 hit.
PfamiPF00717. Peptidase_S24. 1 hit.
[Graphical view]
PRINTSiPR00727. LEADERPTASE.
SUPFAMiSSF51306. SSF51306. 1 hit.
TIGRFAMsiTIGR02227. sigpep_I_bact. 1 hit.
PROSITEiPS00501. SPASE_I_1. 1 hit.
PS00760. SPASE_I_2. 1 hit.
PS00761. SPASE_I_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9RZT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQKKSEWRE WMKAIVVAVL LAGGIRYFIF APIIVDGYSM MPTLHNHERM
60 70 80 90 100
IVNKLAYKIG MPHRFDIIVF HAEEGRDYIK RVIGLPGDRI EYKNDTLYIN
110 120 130 140 150
GKPYEEPYLD EYKKQLSDGG PLTESFTLEE LTGRSTVPPG HLFVMGDNRR
160 170 180
FSKDSRHIGF IPMSKVVGKA NLVYWPLSDA RIVK
Length:184
Mass (Da):21,264
Last modified:November 23, 2009 - v1
Checksum:iF5A4AED5664725A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001794 Genomic DNA. Translation: ACX78603.1.
RefSeqiYP_003253085.1. NC_013411.1.

Genome annotation databases

EnsemblBacteriaiACX78603; ACX78603; GYMC61_1987.
KEGGigyc:GYMC61_1987.
PATRICi32165622. VBIGeoSp85804_2053.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001794 Genomic DNA. Translation: ACX78603.1.
RefSeqiYP_003253085.1. NC_013411.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi544556.GYMC61_1987.

Protein family/group databases

MEROPSiS26.018.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX78603; ACX78603; GYMC61_1987.
KEGGigyc:GYMC61_1987.
PATRICi32165622. VBIGeoSp85804_2053.

Phylogenomic databases

eggNOGiCOG0681.
HOGENOMiHOG000003673.
KOiK03100.
OMAiGKPYEEP.
OrthoDBiEOG622PW8.

Enzyme and pathway databases

BioCyciGSP544556:GI3L-2080-MONOMER.

Family and domain databases

Gene3Di2.10.109.10. 2 hits.
InterProiIPR000223. Pept_S26A_signal_pept_1.
IPR019758. Pept_S26A_signal_pept_1_CS.
IPR019757. Pept_S26A_signal_pept_1_Lys-AS.
IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
IPR028360. Peptidase_S24/S26_b-rbn.
IPR019759. Peptidase_S24_S26.
IPR015927. Peptidase_S24_S26A/B/C.
[Graphical view]
PANTHERiPTHR12383. PTHR12383. 1 hit.
PfamiPF00717. Peptidase_S24. 1 hit.
[Graphical view]
PRINTSiPR00727. LEADERPTASE.
SUPFAMiSSF51306. SSF51306. 1 hit.
TIGRFAMsiTIGR02227. sigpep_I_bact. 1 hit.
PROSITEiPS00501. SPASE_I_1. 1 hit.
PS00760. SPASE_I_2. 1 hit.
PS00761. SPASE_I_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Geobacillus sp. Y412MC61."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Brumm P., Mead D.
    Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y412MC61Imported.

Entry informationi

Entry nameiC9RZT0_GEOSY
AccessioniPrimary (citable) accession number: C9RZT0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 23, 2009
Last sequence update: November 23, 2009
Last modified: March 31, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.