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C9RVI2 (C9RVI2_GEOSY) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU004247 HAMAP-Rule MF_01201

EC=5.1.1.1 RuleBase RU004247 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:GYMC61_1091 EMBL ACX77753.1
OrganismGeobacillus sp. (strain Y412MC61) [Complete proteome] [HAMAP] EMBL ACX77753.1
Taxonomic identifier544556 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length384 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2651Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1361Substrate By similarity HAMAP-Rule MF_01201
Binding site3121Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
C9RVI2 [UniParc].

Last modified November 24, 2009. Version 1.
Checksum: 8008AE12BDA23A52

FASTA38442,923
        10         20         30         40         50         60 
MDEFHRDTWV EIDLDAIYDN VANLRRFLPG GTQIMAVVKA NAYGHGDAQV AATALEAGAS 

        70         80         90        100        110        120 
RLAVAFLDEA LALRKKGIDA PILVLGASRP EDVALAAEHR IALTVFRSDW LEKASSLYNG 

       130        140        150        160        170        180 
STPIHFHLKM DTGMGRLGVK DEEETKRIAA LIDRHPPFVL EGVYTHFATA DEVNTDYFSY 

       190        200        210        220        230        240 
QYARFLHMLD WLPSRPPLVH CANSAAALRF SDRAFNMVRF GISMYGLAPS PDIKPLLPYE 

       250        260        270        280        290        300 
LKEAFSLHSR LVHVKKLQPG EKVSYGATYT AQTEEWIGTI PIGYADGWLR RLQHFHVLVG 

       310        320        330        340        350        360 
GQRAPIVGRI CMDQCMIRLP EPLPVGTKVT LIGRQGDEVI SIDDVARHLG TINYEVPCTI 

       370        380 
SYRVPRIFFR NKRIMEVRNA VGRG 

« Hide

References

[1]"Complete sequence of chromosome of Geobacillus sp. Y412MC61."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Brumm P., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y412MC61 EMBL ACX77753.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001794 Genomic DNA. Translation: ACX77753.1.
RefSeqYP_003252235.1. NC_013411.1.

3D structure databases

ProteinModelPortalC9RVI2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING544556.GYMC61_1091.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX77753; ACX77753; GYMC61_1091.
GeneID8524915.
KEGGgyc:GYMC61_1091.
PATRIC32163712. VBIGeoSp85804_1138.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAITMDQLM.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycGSP544556:GI3L-1144-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC9RVI2_GEOSY
AccessionPrimary (citable) accession number: C9RVI2
Entry history
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)