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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

GYMC61_2755

Organism
Geobacillus sp. (strain Y412MC61)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. (S)-3-amino-2-methylpropionate transaminase activity Source: UniProtKB-EC
  2. 4-aminobutyrate transaminase activity Source: InterPro
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciGSP544556:GI3L-2861-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported (EC:2.6.1.22Imported)
Gene namesi
Ordered Locus Names:GYMC61_2755Imported
OrganismiGeobacillus sp. (strain Y412MC61)Imported
Taxonomic identifieri544556 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
ProteomesiUP000008468: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi544556.GYMC61_2755.

Structurei

3D structure databases

ProteinModelPortaliC9RT92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiNLCAEAN.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9RT92-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKAKTKKYIQ VKTAIPGPKA KELLGKKEEN VPRGPFHTVP TFAVKGEGAL
60 70 80 90 100
LTDVDGNTFI DLAGAIGSLN VGHCPPKVVE AIQKQAEQYI HPCFHVMMYE
110 120 130 140 150
PYVELAETLN RITPGNHSKK TFFLNSGAEA VENAVKIARK YTGRRAILSF
160 170 180 190 200
ERGFHGRTLL AMSLTSKVKP YKFGFGPFAP DTYKLPYPYY YRKPAGMTNE
210 220 230 240 250
ELDAELLRRL EDFFLSDVPA EEVAAIIMEP VQGEGGFIVP SKTFVQGVKR
260 270 280 290 300
ICEKYGILFI ADEIQTGFGR TGKMFAIEHF DVIPDLITMS KSIGAGVPIS
310 320 330 340 350
AVTGRAEVMD APNPGEIGGT YGGSPLGCVA ALEVIRMLQQ EQLVERANVI
360 370 380 390 400
GQIAIDRFRR LQEKYETVGD VRGLGAMVAV EFVTDAKTKT PNKELTAAIL
410 420 430 440
RECHQRGVIV MGAGLYSNVI RLLTPLVITD EQLEEALDVI EEVIAELA
Length:448
Mass (Da):49,167
Last modified:November 24, 2009 - v1
Checksum:i6903C3796508F795
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001794 Genomic DNA. Translation: ACX79337.1.
RefSeqiYP_003253819.1. NC_013411.1.

Genome annotation databases

EnsemblBacteriaiACX79337; ACX79337; GYMC61_2755.
GeneIDi8526632.
KEGGigyc:GYMC61_2755.
PATRICi32167303. VBIGeoSp85804_2880.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001794 Genomic DNA. Translation: ACX79337.1.
RefSeqiYP_003253819.1. NC_013411.1.

3D structure databases

ProteinModelPortaliC9RT92.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi544556.GYMC61_2755.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX79337; ACX79337; GYMC61_2755.
GeneIDi8526632.
KEGGigyc:GYMC61_2755.
PATRICi32167303. VBIGeoSp85804_2880.

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiNLCAEAN.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciGSP544556:GI3L-2861-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Geobacillus sp. Y412MC61."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Brumm P., Mead D.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y412MC61Imported.

Entry informationi

Entry nameiC9RT92_GEOSY
AccessioniPrimary (citable) accession number: C9RT92
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: January 7, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.