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C9RGZ0

- C9RGZ0_METVM

UniProt

C9RGZ0 - C9RGZ0_METVM

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Protein
Ribulose bisphosphate carboxylase
Gene
rbcL, Metvu_0984
Organism
Methanocaldococcus vulcanius (strain ATCC 700851 / DSM 12094 / M7) (Methanococcus vulcanius)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the addition of molecular CO2 and H2O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase By similarity.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei153 – 1531Proton acceptor By similarityUniRule annotation
Binding sitei155 – 1551Substrate By similarityUniRule annotation
Metal bindingi179 – 1791Magnesium; via carbamate group By similarityUniRule annotation
Metal bindingi181 – 1811Magnesium By similarityUniRule annotation
Metal bindingi182 – 1821Magnesium By similarityUniRule annotation
Active sitei269 – 2691Proton acceptor By similarityUniRule annotation
Binding sitei270 – 2701Substrate By similarityUniRule annotation
Binding sitei302 – 3021Substrate By similarityUniRule annotation
Sitei309 – 3091Transition state stabilizer By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. ribulose-bisphosphate carboxylase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, OxidoreductaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMVUL579137:GHFP-995-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylaseUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCOUniRule annotation
Gene namesi
Name:rbcLUniRule annotation
Ordered Locus Names:Metvu_0984Imported
OrganismiMethanocaldococcus vulcanius (strain ATCC 700851 / DSM 12094 / M7) (Methanococcus vulcanius)Imported
Taxonomic identifieri579137 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000002063: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei179 – 1791N6-carboxylysine By similarityUniRule annotation

Interactioni

Subunit structurei

Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi579137.Metvu_0984.

Structurei

3D structure databases

ProteinModelPortaliC9RGZ0.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni353 – 3553Substrate binding By similarityUniRule annotation
Regioni375 – 3784Substrate binding By similarityUniRule annotation

Sequence similaritiesi

Belongs to the RuBisCO large chain family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1850.
HOGENOMiHOG000230831.
KOiK01601.
OMAiFTQDWAS.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProiIPR017712. RuBisCO_III.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsiTIGR03326. rubisco_III. 1 hit.

Sequencei

Sequence statusi: Complete.

C9RGZ0-1 [UniParc]FASTAAdd to Basket

« Hide

MDYINLNYTP KESDLLSCMI IKGDDLKKLA NEIAGESSIG TWTKVQTMKS    50
DIYEKLKPNV YEIKEIGNDG KYKIGLIKIA YPLYDFEINN MPGVLAGIAG 100
NIFGMKIAKG LRILDFRFPK EFIDEYEGPE YGIEGVRNTL KIKERPLLGT 150
IVKPKVGLKT EEHAKVAYEA WVGGVDLVKD DENLTSQDFN KFEDRVYKTL 200
EMRDKAEEET GERKAYMPNI TAPYNEMIRR AEIAEDAESE YVMIDVVVSG 250
FSAVQSFREE NFGFIIHAHR AMHAAMTRSK DFGITMLTLA KIYRLLGVDQ 300
LHIGTVVGKM EGEEREVKAI RDEIVYDKVE ADNEHKFFEQ EWFGLNSVFP 350
VSSGGVHPRL VPKIVEILGR DVIIQAGGGI HGHPDGTRAG AKAMRAAIEA 400
VMEGKPLEEK AEEVIELKKA LEYWK 425
Length:425
Mass (Da):47,952
Last modified:November 24, 2009 - v1
Checksum:iA2E35BB843A5A98C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001787 Genomic DNA. Translation: ACX72842.1.
RefSeqiWP_015733062.1. NC_013407.1.
YP_003247324.1. NC_013407.1.

Genome annotation databases

EnsemblBacteriaiACX72842; ACX72842; Metvu_0984.
GeneIDi8513321.
KEGGimvu:Metvu_0984.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001787 Genomic DNA. Translation: ACX72842.1 .
RefSeqi WP_015733062.1. NC_013407.1.
YP_003247324.1. NC_013407.1.

3D structure databases

ProteinModelPortali C9RGZ0.
ModBasei Search...

Protein-protein interaction databases

STRINGi 579137.Metvu_0984.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACX72842 ; ACX72842 ; Metvu_0984 .
GeneIDi 8513321.
KEGGi mvu:Metvu_0984.

Phylogenomic databases

eggNOGi COG1850.
HOGENOMi HOG000230831.
KOi K01601.
OMAi FTQDWAS.

Enzyme and pathway databases

BioCyci MVUL579137:GHFP-995-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProi IPR017712. RuBisCO_III.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsi TIGR03326. rubisco_III. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700851 / DSM 12094 / M7.

Entry informationi

Entry nameiC9RGZ0_METVM
AccessioniPrimary (citable) accession number: C9RGZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: September 3, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O2 to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains By similarity.UniRule annotation

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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