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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Aggregatibacter actinomycetemcomitans serotype C (strain D11S-1) (Actinobacillus actinomycetemcomitans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotationSAAS annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotation
Ordered Locus Names:D11S_1483Imported
OrganismiAggregatibacter actinomycetemcomitans serotype C (strain D11S-1) (Actinobacillus actinomycetemcomitans)Imported
Taxonomic identifieri668336 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeAggregatibacter
Proteomesi
  • UP000002569 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 149MutHInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the MutH family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000271839
KOiK03573
OMAiPPDLKRD

Family and domain databases

CDDicd00583 MutH_Sau3AI, 1 hit
Gene3Di3.40.600.10, 1 hit
HAMAPiMF_00759 MutH, 1 hit
InterProiView protein in InterPro
IPR004230 DNA_mismatch_repair_MutH
IPR011337 DNA_rep_MutH/RE_typeII
IPR037057 DNA_rep_MutH/RE_typeII_sf
IPR011335 Restrct_endonuc-II-like
PfamiView protein in Pfam
PF02976 MutH, 1 hit
SMARTiView protein in SMART
SM00927 MutH, 1 hit
SUPFAMiSSF52980 SSF52980, 1 hit
TIGRFAMsiTIGR02248 mutH_TIGR, 1 hit

Sequencei

Sequence statusi: Complete.

C9R4X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPQTTEALL SRAQSIAGLT FGELAAQWHI SVPPNLKRDK GWVGMLLETA
60 70 80 90 100
LGATAGSKAE QDFTHLGIEL KTLPINEQGY PLETTFVSLA PLIQNSGVNW
110 120 130 140 150
QNSHVRHKLS RVLWIPIEGS RHIPLAERHI GTPILWQPNE QQEALLKQDW
160 170 180 190 200
EELMDYIVLG QLDKINARLG EVLQLRPKAA NSKALTKGIG KNGEIIDTLP
210 220
LGFYLRKEFT YQILQQFVQQ AI
Length:222
Mass (Da):24,887
Last modified:November 24, 2009 - v1
Checksum:i991A798139F14934
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001733 Genomic DNA Translation: ACX82859.1
RefSeqiWP_005541016.1, NC_013416.2

Genome annotation databases

EnsemblBacteriaiACX82859; ACX82859; D11S_1483
GeneIDi31673667
KEGGiaat:D11S_1483
PATRICifig|668336.12.peg.1437

Similar proteinsi

Entry informationi

Entry nameiC9R4X3_AGGAD
AccessioniPrimary (citable) accession number: C9R4X3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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