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C9R4X3

- C9R4X3_AGGAD

UniProt

C9R4X3 - C9R4X3_AGGAD

Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Aggregatibacter actinomycetemcomitans serotype C (strain D11S-1) (Actinobacillus actinomycetemcomitans)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (24 Nov 2009)
      Previous versions | rss
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    Functioni

    Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. endonuclease activity Source: UniProtKB-KW

    GO - Biological processi

    1. DNA modification Source: InterPro
    2. DNA repair Source: UniProtKB-KW

    Keywords - Molecular functioni

    EndonucleaseUniRule annotationSAAS annotationImported, Hydrolase, Nuclease

    Keywords - Biological processi

    DNA damage, DNA repairUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciAACT668336:GJBF-1481-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA mismatch repair protein MutHUniRule annotation
    Alternative name(s):
    Methyl-directed mismatch repair proteinUniRule annotation
    Gene namesi
    Name:mutHUniRule annotation
    Ordered Locus Names:D11S_1483Imported
    OrganismiAggregatibacter actinomycetemcomitans serotype C (strain D11S-1) (Actinobacillus actinomycetemcomitans)Imported
    Taxonomic identifieri668336 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeAggregatibacter
    ProteomesiUP000002569: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi668336.D11S_1483.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MutH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3066.
    HOGENOMiHOG000271839.
    KOiK03573.
    OMAiLRPKGAN.
    OrthoDBiEOG6CGCC0.

    Family and domain databases

    Gene3Di3.40.600.10. 1 hit.
    HAMAPiMF_00759. MutH.
    InterProiIPR004230. DNA_mismatch_repair_MutH.
    IPR011337. DNA_rep_MutH/RE_typeII.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view]
    PfamiPF02976. MutH. 1 hit.
    [Graphical view]
    SMARTiSM00927. MutH. 1 hit.
    [Graphical view]
    SUPFAMiSSF52980. SSF52980. 1 hit.
    TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C9R4X3-1 [UniParc]FASTAAdd to Basket

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    MIPQTTEALL SRAQSIAGLT FGELAAQWHI SVPPNLKRDK GWVGMLLETA    50
    LGATAGSKAE QDFTHLGIEL KTLPINEQGY PLETTFVSLA PLIQNSGVNW 100
    QNSHVRHKLS RVLWIPIEGS RHIPLAERHI GTPILWQPNE QQEALLKQDW 150
    EELMDYIVLG QLDKINARLG EVLQLRPKAA NSKALTKGIG KNGEIIDTLP 200
    LGFYLRKEFT YQILQQFVQQ AI 222
    Length:222
    Mass (Da):24,887
    Last modified:November 24, 2009 - v1
    Checksum:i991A798139F14934
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001733 Genomic DNA. Translation: ACX82859.1.
    RefSeqiYP_003256078.1. NC_013416.1.

    Genome annotation databases

    EnsemblBacteriaiACX82859; ACX82859; D11S_1483.
    GeneIDi8537202.
    KEGGiaat:D11S_1483.
    PATRICi31913701. VBIAggAct139153_1395.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001733 Genomic DNA. Translation: ACX82859.1 .
    RefSeqi YP_003256078.1. NC_013416.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 668336.D11S_1483.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACX82859 ; ACX82859 ; D11S_1483 .
    GeneIDi 8537202.
    KEGGi aat:D11S_1483.
    PATRICi 31913701. VBIAggAct139153_1395.

    Phylogenomic databases

    eggNOGi COG3066.
    HOGENOMi HOG000271839.
    KOi K03573.
    OMAi LRPKGAN.
    OrthoDBi EOG6CGCC0.

    Enzyme and pathway databases

    BioCyci AACT668336:GJBF-1481-MONOMER.

    Family and domain databases

    Gene3Di 3.40.600.10. 1 hit.
    HAMAPi MF_00759. MutH.
    InterProi IPR004230. DNA_mismatch_repair_MutH.
    IPR011337. DNA_rep_MutH/RE_typeII.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view ]
    Pfami PF02976. MutH. 1 hit.
    [Graphical view ]
    SMARTi SM00927. MutH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52980. SSF52980. 1 hit.
    TIGRFAMsi TIGR02248. mutH_TIGR. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Aggregatibacter actinomycetemcomitans serotype c strain D11S-1."
      Chen C., Kittichotirat W., Si Y., Bumgarner R.
      J. Bacteriol. 191:7378-7379(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: D11S-1Imported.

    Entry informationi

    Entry nameiC9R4X3_AGGAD
    AccessioniPrimary (citable) accession number: C9R4X3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 24, 2009
    Last sequence update: November 24, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3