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C9R4X3

- C9R4X3_AGGAD

UniProt

C9R4X3 - C9R4X3_AGGAD

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Protein
DNA mismatch repair protein MutH
Gene
mutH, D11S_1483
Organism
Aggregatibacter actinomycetemcomitans serotype C (strain D11S-1) (Actinobacillus actinomycetemcomitans)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair By similarity.UniRule annotationSAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. endonuclease activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA modification Source: InterPro
  2. DNA repair Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseUniRule annotationSAAS annotationsImported, Hydrolase, Nuclease

Keywords - Biological processi

DNA damage, DNA repairUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAACT668336:GJBF-1481-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotation
Alternative name(s):
Methyl-directed mismatch repair protein
Gene namesi
Name:mutHUniRule annotation
Ordered Locus Names:D11S_1483Imported
OrganismiAggregatibacter actinomycetemcomitans serotype C (strain D11S-1) (Actinobacillus actinomycetemcomitans)Imported
Taxonomic identifieri668336 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeAggregatibacter
ProteomesiUP000002569: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi668336.D11S_1483.

Family & Domainsi

Sequence similaritiesi

Belongs to the MutH family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3066.
HOGENOMiHOG000271839.
KOiK03573.
OMAiLRPKGAN.
OrthoDBiEOG6CGCC0.

Family and domain databases

Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH.
InterProiIPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
[Graphical view]
PfamiPF02976. MutH. 1 hit.
[Graphical view]
SMARTiSM00927. MutH. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

Sequencei

Sequence statusi: Complete.

C9R4X3-1 [UniParc]FASTAAdd to Basket

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MIPQTTEALL SRAQSIAGLT FGELAAQWHI SVPPNLKRDK GWVGMLLETA    50
LGATAGSKAE QDFTHLGIEL KTLPINEQGY PLETTFVSLA PLIQNSGVNW 100
QNSHVRHKLS RVLWIPIEGS RHIPLAERHI GTPILWQPNE QQEALLKQDW 150
EELMDYIVLG QLDKINARLG EVLQLRPKAA NSKALTKGIG KNGEIIDTLP 200
LGFYLRKEFT YQILQQFVQQ AI 222
Length:222
Mass (Da):24,887
Last modified:November 24, 2009 - v1
Checksum:i991A798139F14934
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001733 Genomic DNA. Translation: ACX82859.1.
RefSeqiYP_003256078.1. NC_013416.1.

Genome annotation databases

EnsemblBacteriaiACX82859; ACX82859; D11S_1483.
GeneIDi8537202.
KEGGiaat:D11S_1483.
PATRICi31913701. VBIAggAct139153_1395.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001733 Genomic DNA. Translation: ACX82859.1 .
RefSeqi YP_003256078.1. NC_013416.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 668336.D11S_1483.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACX82859 ; ACX82859 ; D11S_1483 .
GeneIDi 8537202.
KEGGi aat:D11S_1483.
PATRICi 31913701. VBIAggAct139153_1395.

Phylogenomic databases

eggNOGi COG3066.
HOGENOMi HOG000271839.
KOi K03573.
OMAi LRPKGAN.
OrthoDBi EOG6CGCC0.

Enzyme and pathway databases

BioCyci AACT668336:GJBF-1481-MONOMER.

Family and domain databases

Gene3Di 3.40.600.10. 1 hit.
HAMAPi MF_00759. MutH.
InterProi IPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR011335. Restrct_endonuc-II-like.
[Graphical view ]
Pfami PF02976. MutH. 1 hit.
[Graphical view ]
SMARTi SM00927. MutH. 1 hit.
[Graphical view ]
SUPFAMi SSF52980. SSF52980. 1 hit.
TIGRFAMsi TIGR02248. mutH_TIGR. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Aggregatibacter actinomycetemcomitans serotype c strain D11S-1."
    Chen C., Kittichotirat W., Si Y., Bumgarner R.
    J. Bacteriol. 191:7378-7379(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D11S-1.

Entry informationi

Entry nameiC9R4X3_AGGAD
AccessioniPrimary (citable) accession number: C9R4X3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: April 16, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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