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C9R146

- C9R146_ECOD1

UniProt

C9R146 - C9R146_ECOD1

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Protein
RNA polymerase sigma factor
Gene
rpoE, EcDH1_1095, ECDH1ME8569_2500
Organism
Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
  4. sigma factor activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Sigma factorUniRule annotationSAAS annotations

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
Gene namesi
Name:rpoEImported
Ordered Locus Names:EcDH1_1095Imported, ECDH1ME8569_2500Imported
OrganismiEscherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)Imported
Taxonomic identifieri536056 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000004998: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymeraseImported

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2MAONMR-A1-92[»]
2MAPNMR-A1-92[»]

Family & Domainsi

Sequence similaritiesi

Belongs to the sigma-70 factor family. ECF subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000094755.
KOiK03088.
OMAiIDNKIQP.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR000838. RNA_pol_sigma70_ECF_CS.
IPR007627. RNA_pol_sigma70_r2.
IPR013249. RNA_pol_sigma70_r4_t2.
IPR014286. RNA_pol_sigma70_RpoE.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF08281. Sigma70_r4_2. 1 hit.
[Graphical view]
SUPFAMiSSF88659. SSF88659. 1 hit.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02939. RpoE_Sigma70. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiPS01063. SIGMA70_ECF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9R146-1 [UniParc]FASTAAdd to Basket

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MSEQLTDQVL VERVQKGDQK AFNLLVVRYQ HKVASLVSRY VPSGDVPDVV    50
QEAFIKAYRA LDSFRGDSAF YTWLYRIAVN TAKNYLVAQG RRPPSSDVDA 100
IEAENFESGG ALKEISNPEN LMLSEELRQI VFRTIESLPE DLRMAITLRE 150
LDGLSYEEIA AIMDCPVGTV RSRIFRAREA IDNKVQPLIR R 191
Length:191
Mass (Da):21,696
Last modified:November 24, 2009 - v1
Checksum:iC71EEF5939C3611E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001637 Genomic DNA. Translation: ACX38769.1.
AP012030 Genomic DNA. Translation: BAJ44356.1.
RefSeqiYP_006091058.1. NC_017625.1.
YP_006129901.1. NC_017638.1.

Genome annotation databases

EnsemblBacteriaiACX38769; ACX38769; EcDH1_1095.
BAJ44356; BAJ44356; ECDH1ME8569_2500.
GeneIDi12704680.
12870299.
KEGGiedh:EcDH1_1095.
edj:ECDH1ME8569_2500.
PATRICi36694329. VBIEscCol36761_1152.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001637 Genomic DNA. Translation: ACX38769.1 .
AP012030 Genomic DNA. Translation: BAJ44356.1 .
RefSeqi YP_006091058.1. NC_017625.1.
YP_006129901.1. NC_017638.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2MAO NMR - A 1-92 [» ]
2MAP NMR - A 1-92 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACX38769 ; ACX38769 ; EcDH1_1095 .
BAJ44356 ; BAJ44356 ; ECDH1ME8569_2500 .
GeneIDi 12704680.
12870299.
KEGGi edh:EcDH1_1095.
edj:ECDH1ME8569_2500.
PATRICi 36694329. VBIEscCol36761_1152.

Phylogenomic databases

HOGENOMi HOG000094755.
KOi K03088.
OMAi IDNKIQP.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR014284. RNA_pol_sigma-70_dom.
IPR000838. RNA_pol_sigma70_ECF_CS.
IPR007627. RNA_pol_sigma70_r2.
IPR013249. RNA_pol_sigma70_r4_t2.
IPR014286. RNA_pol_sigma70_RpoE.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF04542. Sigma70_r2. 1 hit.
PF08281. Sigma70_r4_2. 1 hit.
[Graphical view ]
SUPFAMi SSF88659. SSF88659. 1 hit.
SSF88946. SSF88946. 1 hit.
TIGRFAMsi TIGR02939. RpoE_Sigma70. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEi PS01063. SIGMA70_ECF. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1 and DH1Imported.
  2. "Comparison of sequence reads obtained from three next-generation sequencing platforms."
    Suzuki S., Ono N., Furusawa C., Ying B.-W., Yomo T.
    PLoS ONE 6:E19534-E19534(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1 and DH1Imported.
  3. "Structural basis for -10 promoter element melting by environmentally induced sigma factors."
    Campagne S., Marsh M.E., Capitani G., Vorholt J.A., Allain F.H.
    Nat. Struct. Mol. Biol. 21:269-276(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 1-92.

Entry informationi

Entry nameiC9R146_ECOD1
AccessioniPrimary (citable) accession number: C9R146
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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