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C9R146

- C9R146_ECOD1

UniProt

C9R146 - C9R146_ECOD1

Protein

RNA polymerase sigma factor

Gene

rpoE

Organism
Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (24 Nov 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
    3. sequence-specific DNA binding transcription factor activity Source: InterPro
    4. sigma factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: InterPro

    Keywords - Molecular functioni

    Sigma factorUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA polymerase sigma factorUniRule annotation
    Gene namesi
    Name:rpoEImported
    Ordered Locus Names:EcDH1_1095Imported, ECDH1ME8569_2500Imported
    OrganismiEscherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)Imported
    Taxonomic identifieri536056 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000002619: Chromosome

    Subcellular locationi

    Keywords - Cellular componenti

    DNA-directed RNA polymeraseImported

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2MAONMR-A1-92[»]
    2MAPNMR-A1-92[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the sigma-70 factor family. ECF subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000094755.
    KOiK03088.
    OMAiIDNKIQP.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR014284. RNA_pol_sigma-70_dom.
    IPR000838. RNA_pol_sigma70_ECF_CS.
    IPR007627. RNA_pol_sigma70_r2.
    IPR013249. RNA_pol_sigma70_r4_t2.
    IPR014286. RNA_pol_sigma70_RpoE.
    IPR013325. RNA_pol_sigma_r2.
    IPR013324. RNA_pol_sigma_r3_r4.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF04542. Sigma70_r2. 1 hit.
    PF08281. Sigma70_r4_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF88659. SSF88659. 1 hit.
    SSF88946. SSF88946. 1 hit.
    TIGRFAMsiTIGR02939. RpoE_Sigma70. 1 hit.
    TIGR02937. sigma70-ECF. 1 hit.
    PROSITEiPS01063. SIGMA70_ECF. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C9R146-1 [UniParc]FASTAAdd to Basket

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    MSEQLTDQVL VERVQKGDQK AFNLLVVRYQ HKVASLVSRY VPSGDVPDVV    50
    QEAFIKAYRA LDSFRGDSAF YTWLYRIAVN TAKNYLVAQG RRPPSSDVDA 100
    IEAENFESGG ALKEISNPEN LMLSEELRQI VFRTIESLPE DLRMAITLRE 150
    LDGLSYEEIA AIMDCPVGTV RSRIFRAREA IDNKVQPLIR R 191
    Length:191
    Mass (Da):21,696
    Last modified:November 24, 2009 - v1
    Checksum:iC71EEF5939C3611E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001637 Genomic DNA. Translation: ACX38769.1.
    AP012030 Genomic DNA. Translation: BAJ44356.1.
    RefSeqiYP_006091058.1. NC_017625.1.
    YP_006129901.1. NC_017638.1.

    Genome annotation databases

    EnsemblBacteriaiACX38769; ACX38769; EcDH1_1095.
    BAJ44356; BAJ44356; ECDH1ME8569_2500.
    GeneIDi12704680.
    12870299.
    KEGGiedh:EcDH1_1095.
    edj:ECDH1ME8569_2500.
    PATRICi36694329. VBIEscCol36761_1152.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001637 Genomic DNA. Translation: ACX38769.1 .
    AP012030 Genomic DNA. Translation: BAJ44356.1 .
    RefSeqi YP_006091058.1. NC_017625.1.
    YP_006129901.1. NC_017638.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2MAO NMR - A 1-92 [» ]
    2MAP NMR - A 1-92 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACX38769 ; ACX38769 ; EcDH1_1095 .
    BAJ44356 ; BAJ44356 ; ECDH1ME8569_2500 .
    GeneIDi 12704680.
    12870299.
    KEGGi edh:EcDH1_1095.
    edj:ECDH1ME8569_2500.
    PATRICi 36694329. VBIEscCol36761_1152.

    Phylogenomic databases

    HOGENOMi HOG000094755.
    KOi K03088.
    OMAi IDNKIQP.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR014284. RNA_pol_sigma-70_dom.
    IPR000838. RNA_pol_sigma70_ECF_CS.
    IPR007627. RNA_pol_sigma70_r2.
    IPR013249. RNA_pol_sigma70_r4_t2.
    IPR014286. RNA_pol_sigma70_RpoE.
    IPR013325. RNA_pol_sigma_r2.
    IPR013324. RNA_pol_sigma_r3_r4.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF04542. Sigma70_r2. 1 hit.
    PF08281. Sigma70_r4_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF88659. SSF88659. 1 hit.
    SSF88946. SSF88946. 1 hit.
    TIGRFAMsi TIGR02939. RpoE_Sigma70. 1 hit.
    TIGR02937. sigma70-ECF. 1 hit.
    PROSITEi PS01063. SIGMA70_ECF. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1Imported and DH1Imported.
    2. "Comparison of sequence reads obtained from three next-generation sequencing platforms."
      Suzuki S., Ono N., Furusawa C., Ying B.-W., Yomo T.
      PLoS ONE 6:E19534-E19534(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DH1Imported.
    3. "Structural basis for -10 promoter element melting by environmentally induced sigma factors."
      Campagne S., Marsh M.E., Capitani G., Vorholt J.A., Allain F.H.
      Nat. Struct. Mol. Biol. 21:269-276(2014) [PubMed] [Europe PMC] [Abstract]
      Cited for: STRUCTURE BY NMR OF 1-92.

    Entry informationi

    Entry nameiC9R146_ECOD1
    AccessioniPrimary (citable) accession number: C9R146
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 24, 2009
    Last sequence update: November 24, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3