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Protein

RNA polymerase sigma factor

Gene

rpoE

Organism
Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
  4. sigma factor activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA-templated transcription, initiation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Sigma factorUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma factorUniRule annotation
Gene namesi
Name:rpoEImported
Ordered Locus Names:EcDH1_1095Imported, ECDH1ME8569_2500Imported
OrganismiEscherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)Imported
Taxonomic identifieri536056 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000002619: Chromosome, UP000004998: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymeraseImported

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2MAONMR-A1-92[»]
2MAPNMR-A1-92[»]
ProteinModelPortaliC9R146.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sigma-70 factor family. ECF subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000094755.
KOiK03088.
OMAiDAENYES.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR000838. RNA_pol_sigma70_ECF_CS.
IPR007627. RNA_pol_sigma70_r2.
IPR013249. RNA_pol_sigma70_r4_t2.
IPR014286. RNA_pol_sigma70_RpoE.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF08281. Sigma70_r4_2. 1 hit.
[Graphical view]
SUPFAMiSSF88659. SSF88659. 1 hit.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02939. RpoE_Sigma70. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiPS01063. SIGMA70_ECF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9R146-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSEQLTDQVL VERVQKGDQK AFNLLVVRYQ HKVASLVSRY VPSGDVPDVV
60 70 80 90 100
QEAFIKAYRA LDSFRGDSAF YTWLYRIAVN TAKNYLVAQG RRPPSSDVDA
110 120 130 140 150
IEAENFESGG ALKEISNPEN LMLSEELRQI VFRTIESLPE DLRMAITLRE
160 170 180 190
LDGLSYEEIA AIMDCPVGTV RSRIFRAREA IDNKVQPLIR R
Length:191
Mass (Da):21,696
Last modified:November 24, 2009 - v1
Checksum:iC71EEF5939C3611E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001637 Genomic DNA. Translation: ACX38769.1.
AP012030 Genomic DNA. Translation: BAJ44356.1.
RefSeqiYP_006091058.1. NC_017625.1.
YP_006129901.1. NC_017638.1.

Genome annotation databases

EnsemblBacteriaiACX38769; ACX38769; EcDH1_1095.
BAJ44356; BAJ44356; ECDH1ME8569_2500.
GeneIDi12704680.
12870299.
KEGGiedh:EcDH1_1095.
edj:ECDH1ME8569_2500.
PATRICi36694329. VBIEscCol36761_1152.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001637 Genomic DNA. Translation: ACX38769.1.
AP012030 Genomic DNA. Translation: BAJ44356.1.
RefSeqiYP_006091058.1. NC_017625.1.
YP_006129901.1. NC_017638.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2MAONMR-A1-92[»]
2MAPNMR-A1-92[»]
ProteinModelPortaliC9R146.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX38769; ACX38769; EcDH1_1095.
BAJ44356; BAJ44356; ECDH1ME8569_2500.
GeneIDi12704680.
12870299.
KEGGiedh:EcDH1_1095.
edj:ECDH1ME8569_2500.
PATRICi36694329. VBIEscCol36761_1152.

Phylogenomic databases

HOGENOMiHOG000094755.
KOiK03088.
OMAiDAENYES.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR014284. RNA_pol_sigma-70_dom.
IPR000838. RNA_pol_sigma70_ECF_CS.
IPR007627. RNA_pol_sigma70_r2.
IPR013249. RNA_pol_sigma70_r4_t2.
IPR014286. RNA_pol_sigma70_RpoE.
IPR013325. RNA_pol_sigma_r2.
IPR013324. RNA_pol_sigma_r3_r4.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04542. Sigma70_r2. 1 hit.
PF08281. Sigma70_r4_2. 1 hit.
[Graphical view]
SUPFAMiSSF88659. SSF88659. 1 hit.
SSF88946. SSF88946. 1 hit.
TIGRFAMsiTIGR02939. RpoE_Sigma70. 1 hit.
TIGR02937. sigma70-ECF. 1 hit.
PROSITEiPS01063. SIGMA70_ECF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1Imported and DH1Imported.
  2. "Comparison of sequence reads obtained from three next-generation sequencing platforms."
    Suzuki S., Ono N., Furusawa C., Ying B.-W., Yomo T.
    PLoS ONE 6:E19534-E19534(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1Imported and DH1Imported.
  3. "Structural basis for -10 promoter element melting by environmentally induced sigma factors."
    Campagne S., Marsh M.E., Capitani G., Vorholt J.A., Allain F.H.
    Nat. Struct. Mol. Biol. 21:269-276(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 1-92.

Entry informationi

Entry nameiC9R146_ECOD1
AccessioniPrimary (citable) accession number: C9R146
Entry historyi
Integrated into UniProtKB/TrEMBL: November 24, 2009
Last sequence update: November 24, 2009
Last modified: February 4, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.