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C9QVN0

- C9QVN0_ECOD1

UniProt

C9QVN0 - C9QVN0_ECOD1

Protein

Glutamate decarboxylase

Gene

gadA

Organism
Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (24 Nov 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Name:gadAImported
    Ordered Locus Names:EcDH1_0196Imported, ECDH1ME8569_3396Imported
    OrganismiEscherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1)Imported
    Taxonomic identifieri536056 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000002619: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliC9QVN0.
    SMRiC9QVN0. Positions 4-452.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiMIGRLFN.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
    PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C9QVN0-1 [UniParc]FASTAAdd to Basket

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    MDQKLLTDFR SELLDSRFGA KAISTIAESK RFPLHEMRDD VAFQIINDEL    50
    YLDGNARQNL ATFCQTWDDE NVHKLMDLSI NKNWIDKEEY PQSAAIDLRC 100
    VNMVADLWHA PAPKNGQAVG TNTIGSSEAC MLGGMAMKWR WRKRMEAAGK 150
    PTDKPNLVCG PVQICWHKFA RYWDVELREI PMRPGQLFMD PKRMIEACDE 200
    NTIGVVPTFG VTYTGNYEFP QPLHDALDKF QADTGIDIDM HIDAASGGFL 250
    APFVAPDIVW DFRLPRVKSI SASGHKFGLA PLGCGWVIWR DEEALPQELV 300
    FNVDYLGGQI GTFAINFSRP AGQVIAQYYE FLRLGREGYT KVQNASYQVA 350
    AYLADEIAKL GPYEFICTGR PDEGIPAVCF KLKDGEDPGY TLYDLSERLR 400
    LRGWQVPAFT LGGEATDIVV MRIMCRRGFE MDFAELLLED YKASLKYLSD 450
    HPKLQGIAQQ NSFKHT 466
    Length:466
    Mass (Da):52,685
    Last modified:November 24, 2009 - v1
    Checksum:i86F963E710553E22
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001637 Genomic DNA. Translation: ACX37890.1.
    AP012030 Genomic DNA. Translation: BAJ45252.1.
    RefSeqiYP_006090179.1. NC_017625.1.
    YP_006130797.1. NC_017638.1.

    Genome annotation databases

    EnsemblBacteriaiACX37890; ACX37890; EcDH1_0196.
    BAJ45252; BAJ45252; ECDH1ME8569_3396.
    GeneIDi12703755.
    12871008.
    KEGGiedh:EcDH1_0196.
    edj:ECDH1ME8569_3396.
    PATRICi36692377. VBIEscCol36761_0202.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001637 Genomic DNA. Translation: ACX37890.1 .
    AP012030 Genomic DNA. Translation: BAJ45252.1 .
    RefSeqi YP_006090179.1. NC_017625.1.
    YP_006130797.1. NC_017638.1.

    3D structure databases

    ProteinModelPortali C9QVN0.
    SMRi C9QVN0. Positions 4-452.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACX37890 ; ACX37890 ; EcDH1_0196 .
    BAJ45252 ; BAJ45252 ; ECDH1ME8569_3396 .
    GeneIDi 12703755.
    12871008.
    KEGGi edh:EcDH1_0196.
    edj:ECDH1ME8569_3396.
    PATRICi 36692377. VBIEscCol36761_0202.

    Phylogenomic databases

    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi MIGRLFN.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1Imported and DH1Imported.
    2. "Comparison of sequence reads obtained from three next-generation sequencing platforms."
      Suzuki S., Ono N., Furusawa C., Ying B.-W., Yomo T.
      PLoS ONE 6:E19534-E19534(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DH1Imported.

    Entry informationi

    Entry nameiC9QVN0_ECOD1
    AccessioniPrimary (citable) accession number: C9QVN0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 24, 2009
    Last sequence update: November 24, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3