C9QVB2 (C9QVB2_ECOD1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595

Gene names

Name:	ppc HAMAP-Rule MF_00595 EMBL BAJ45680.1
Ordered Locus Names:	EcDH1_4030, ECDH1ME8569_3824 EMBL BAJ45680.1

Organism

Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1) [Complete proteome] [HAMAP] EMBL ACX41630.1

Taxonomic identifier

536056 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	883 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. SAAS SAAS022805 HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. SAAS SAAS021135 HAMAP-Rule MF_00595
Cofactor	Magnesium By similarity. SAAS SAAS021135 HAMAP-Rule MF_00595
Subunit structure	Homotetramer By similarity. HAMAP-Rule MF_00595
Sequence similarities	Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Ontologies

Keywords
Biological process	Carbon dioxide fixation SAAS SAAS021135 HAMAP-Rule MF_00595
Ligand	Magnesium SAAS SAAS021135 HAMAP-Rule MF_00595 Pyruvate EMBL ACX41630.1
Molecular function	Lyase SAAS SAAS021135 HAMAP-Rule MF_00595 EMBL ACX41630.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	138	1	By similarity HAMAP-Rule MF_00595
	Active site	546	1	By similarity HAMAP-Rule MF_00595

Sequences

	Sequence		Length	Mass (Da)
	C9QVB2 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 2620A776CF1F2EBC	FASTA	883	99,063
	10 20 30 40 50 60 MNEQYSALRS NVSMLGKVLG ETIKDALGEH ILERVETIRK LSKSSRAGND ANRQELLTTL 70 80 90 100 110 120 QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPKGEAASN PEVIARTLRK LKNQPELSED 130 140 150 160 170 180 TIKKAVESLS LELVLTAHPT EITRRTLIHK MVEVNACLKQ LDNKDIADYE HNQLMRRLRQ 190 200 210 220 230 240 LIAQSWHTDE IRKLRPSPVD EAKWGFAVVE NSLWQGVPNY LRELNEQLEE NLGYKLPVEF 250 260 270 280 290 300 VPVRFTSWMG GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDIQVLVSEL SMVEATPELL 310 320 330 340 350 360 ALVGEEGAAE PYRYLMKNLR SRLMATQAWL EARLKGEELP KPEGLLTQNE ELWEPLYACY 370 380 390 400 410 420 QSLQACGMGI IANGDLLDTL RRVKCFGVPL VRIDIRQEST RHTEALGELT RYLGIGDYES 430 440 450 460 470 480 WSEADKQAFL IRELNSKRPL LPRNWQPSAE TREVLDTCQV IAEAPQGSIA AYVISMAKTP 490 500 510 520 530 540 SDVLAVHLLL KEAGIGFAMP VAPLFETLDD LNNANDVMTQ LLNIDWYRGL IQGKQMVMIG 550 560 570 580 590 600 YSDSAKDAGV MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP 610 620 630 640 650 660 PGSLKGGLRV TEQGEMIRFK YGLPEITVSS LSLYTGAILE ANLLPPPEPK ESWRRIMDEL 670 680 690 700 710 720 SVISCDVYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP AKRRPTGGVE SLRAIPWIFA 730 740 750 760 770 780 WTQNRLMLPA WLGAGTALQK VVEDGKQSEL EAMCRDWPFF STRLGMLEMV FAKADLWLAE 790 800 810 820 830 840 YYDQRLVDKA LWPLGKELRN LQEEDIKVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN 850 860 870 880 VLQAELLHRS RQAEKEGQEP DPRVEQALMV TIAGIAAGMR NTG

References

[1]

"Complete sequence of Escherichia coli DH1." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Keasling J.D. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1.

[2]

"Comparison of sequence reads obtained from three next-generation sequencing platforms." Suzuki S., Ono N., Furusawa C., Ying B.-W., Yomo T. PLoS ONE 6:e19534-e19534(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1 and DH1 EMBL BAJ45680.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001637 Genomic DNA. Translation: ACX41630.1. AP012030 Genomic DNA. Translation: BAJ45680.1.
RefSeq	YP_006093919.1. NC_017625.1. YP_006131225.1. NC_017638.1.
3D structure databases
SMR	C9QVB2. Positions 4-883.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACX41630; ACX41630; EcDH1_4030. BAJ45680; BAJ45680; ECDH1ME8569_3824.
GeneID	12707684. 12873737.
KEGG	edh:EcDH1_4030. edj:ECDH1ME8569_3824.
PATRIC	36700736. VBIEscCol36761_4283.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000238648.
KO	K01595.
OMA	AIPWVFG.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase-like_dom. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C9QVB2_ECOD1

Accession

Primary (citable) accession number: C9QVB2

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	May 29, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)