C9QUE6 (C9QUE6_ECOD1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr EMBL BAJ45766.1
Ordered Locus Names:	EcDH1_3940, ECDH1ME8569_3910 EMBL BAJ45766.1

Organism

Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1) [Complete proteome] [HAMAP] EMBL ACX41540.1

Taxonomic identifier

536056 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 EMBL ACX41540.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C9QUE6 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: FDE9B438115342C2	FASTA	359	39,153
	10 20 30 40 50 60 MQAATVVINR RALRHNLQRL RELAPASKMV AVVKANAYGH GLLETARTLP DADAFGVARL 70 80 90 100 110 120 EEALRLRAGG ITKPVLLLEG FFDARDLPTI SAQHFHTAVH NEEQLAALEE ASLDEPVTVW 130 140 150 160 170 180 MKLDTGMHRL GVRPEQAEAF YHRLTQCKNV RQPVNIVSHF ARADEPKCGA TEKQLAIFNT 190 200 210 220 230 240 FCEGKPGQRS IAASGGILLW PQSHFDWVRP GIILYGVSPL EDRSTGADFG CQPVMSLTSS 250 260 270 280 290 300 LIAVREHKAG EPVGYGGTWV SERDTRLGVV AMGYGDGYPR AAPSGTPVLV NGREVPIVGR 310 320 330 340 350 VAMDMICVDL GPQAQDKAGD PVILWGEGLP VERIAEMTKV SAYELITRLT SRVAMKYVD

References

[1]

"Complete sequence of Escherichia coli DH1." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Keasling J.D. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1.

[2]

"Comparison of sequence reads obtained from three next-generation sequencing platforms." Suzuki S., Ono N., Furusawa C., Ying B.W., Yomo T. PLoS ONE 6:E19534-E19534(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1 and DH1 EMBL BAJ45766.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001637 Genomic DNA. Translation: ACX41540.1. AP012030 Genomic DNA. Translation: BAJ45766.1.
RefSeq	YP_006093829.1. NC_017625.1. YP_006131311.1. NC_017638.1.
3D structure databases
SMR	C9QUE6. Positions 1-359.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACX41540; ACX41540; EcDH1_3940. BAJ45766; BAJ45766; ECDH1ME8569_3910.
GeneID	12707582. 12871823.
KEGG	edh:EcDH1_3940. edj:ECDH1ME8569_3910.
PATRIC	36700522. VBIEscCol36761_4188.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031446.
KO	K01775.
OMA	HQLETAV.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C9QUE6_ECOD1

Accession

Primary (citable) accession number: C9QUE6

Entry history

Integrated into UniProtKB/TrEMBL:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)