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C9K0E8

- C9K0E8_HUMAN

UniProt

C9K0E8 - C9K0E8_HUMAN

Protein
Submitted name:

Probable ATP-dependent RNA helicase DDX11

Gene

DDX11

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 2 (28 Jun 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. ATP-dependent DNA helicase activity Source: InterPro
    3. DNA binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Probable ATP-dependent RNA helicase DDX11Imported
    Gene namesi
    Name:DDX11Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:2736. DDX11.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: HPA

    Expressioni

    Gene expression databases

    ArrayExpressiC9K0E8.
    BgeeiC9K0E8.

    Structurei

    3D structure databases

    ProteinModelPortaliC9K0E8.
    SMRiC9K0E8. Positions 15-59.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000070023.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    InterProiIPR028331. DDX11/DDX12.
    IPR010614. DEAD_2.
    IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
    IPR006554. Helicase-like_DEXD_c2.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR11472:SF35. PTHR11472:SF35. 1 hit.
    PfamiPF06733. DEAD_2. 1 hit.
    [Graphical view]
    SMARTiSM00488. DEXDc2. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 2 hits.
    PROSITEiPS51193. HELICASE_ATP_BIND_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    C9K0E8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MANETQKVGA IHFPFPFTPY SIQEDFMAEL YRVLEAGKIG IFESPTGTGK    50
    SLSLICGALS WLRDFEQKKR EEEARLLETG TGPLHDEKDE SLCLSSSCEG 100
    AAGTPRPAGE PAWVTQFVQK KEERDLVDRL KRQEEEEREN LLRLSREMLE 150
    TGPEAERLEQ LESGEEELVL AEYESDEEKK VASRVDEDED DLEEEHITKI 200
    YYCSRTHSQL AQFVHEVKKS PFGKDVRLVS LGSRQNLCVN EDVKSLGSVQ 250
    LINDRCVDMQ RSRHEKKKGA EEEKPKRRRQ EKQAACPFYN HEQMGLLRDE 300
    AL 302
    Length:302
    Mass (Da):34,649
    Last modified:June 28, 2011 - v2
    Checksum:iD03F606FCCBCCEEB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei302 – 3021Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008013 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000438391; ENSP00000407646; ENSG00000013573.
    UCSCiuc001qvo.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC008013 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9K0E8.
    SMRi C9K0E8. Positions 15-59.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000438391 ; ENSP00000407646 ; ENSG00000013573 .
    UCSCi uc001qvo.2. human.

    Organism-specific databases

    HGNCi HGNC:2736. DDX11.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000070023.

    Miscellaneous databases

    NextBioi 35488572.

    Gene expression databases

    ArrayExpressi C9K0E8.
    Bgeei C9K0E8.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    InterProi IPR028331. DDX11/DDX12.
    IPR010614. DEAD_2.
    IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
    IPR006554. Helicase-like_DEXD_c2.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR11472:SF35. PTHR11472:SF35. 1 hit.
    Pfami PF06733. DEAD_2. 1 hit.
    [Graphical view ]
    SMARTi SM00488. DEXDc2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 2 hits.
    PROSITEi PS51193. HELICASE_ATP_BIND_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The finished DNA sequence of human chromosome 12."
      Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9K0E8_HUMAN
    AccessioniPrimary (citable) accession number: C9K0E8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: June 28, 2011
    Last modified: October 1, 2014
    This is version 33 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3