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Protein
Submitted name:

Probable ATP-dependent DNA helicase DDX11

Gene

DDX11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Probable ATP-dependent DNA helicase DDX11Imported
Gene namesi
Name:DDX11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:2736. DDX11.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PeptideAtlasiC9K0E8.

Expressioni

Gene expression databases

BgeeiENSG00000013573.
ExpressionAtlasiC9K0E8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9K0E8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 302294Helicase ATP-bindingInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili120 – 15132Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00530000063199.
HOGENOMiHOG000070023.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR010614. DEAD_2.
IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
IPR006554. Helicase-like_DEXD_c2.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF06733. DEAD_2. 1 hit.
[Graphical view]
SMARTiSM00488. DEXDc2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51193. HELICASE_ATP_BIND_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C9K0E8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANETQKVGA IHFPFPFTPY SIQEDFMAEL YRVLEAGKIG IFESPTGTGK
60 70 80 90 100
SLSLICGALS WLRDFEQKKR EEEARLLETG TGPLHDEKDE SLCLSSSCEG
110 120 130 140 150
AAGTPRPAGE PAWVTQFVQK KEERDLVDRL KRQEEEEREN LLRLSREMLE
160 170 180 190 200
TGPEAERLEQ LESGEEELVL AEYESDEEKK VASRVDEDED DLEEEHITKI
210 220 230 240 250
YYCSRTHSQL AQFVHEVKKS PFGKDVRLVS LGSRQNLCVN EDVKSLGSVQ
260 270 280 290 300
LINDRCVDMQ RSRHEKKKGA EEEKPKRRRQ EKQAACPFYN HEQMGLLRDE

AL
Length:302
Mass (Da):34,649
Last modified:June 28, 2011 - v2
Checksum:iD03F606FCCBCCEEB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei302 – 3021Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008013 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000438391; ENSP00000407646; ENSG00000013573.
UCSCiuc058mlc.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008013 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9K0E8.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiC9K0E8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000438391; ENSP00000407646; ENSG00000013573.
UCSCiuc058mlc.1. human.

Organism-specific databases

HGNCiHGNC:2736. DDX11.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000063199.
HOGENOMiHOG000070023.

Gene expression databases

BgeeiENSG00000013573.
ExpressionAtlasiC9K0E8. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR010614. DEAD_2.
IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
IPR006554. Helicase-like_DEXD_c2.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF06733. DEAD_2. 1 hit.
[Graphical view]
SMARTiSM00488. DEXDc2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51193. HELICASE_ATP_BIND_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC9K0E8_HUMAN
AccessioniPrimary (citable) accession number: C9K0E8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: June 28, 2011
Last modified: September 7, 2016
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.