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Protein
Submitted name:

T-cell immunoreceptor with Ig and ITIM domains

Gene

TIGIT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
T-cell immunoreceptor with Ig and ITIM domainsImported
Gene namesi
Name:TIGITImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi

Organism-specific databases

EuPathDBiHostDB:ENSG00000181847.11
HGNCiHGNC:26838 TIGIT

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei121 – 142HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000181847

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JZW6

Expressioni

Gene expression databases

BgeeiENSG00000181847
ExpressionAtlasiC9JZW6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JZW6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 87Ig-likeInterPro annotationAdd BLAST87

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410JBCH Eukaryota
ENOG4111CNN LUCA
GeneTreeiENSGT00390000012671
HOGENOMiHOG000154582

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Fragment.

C9JZW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTGTIETTG NISAEKGGSI ILQCHLSSTT AQVTQVNWEQ QDQLLAICNA
60 70 80 90 100
DLGWHISPSF KDRVAPGPGL GLTLQSLTVN DTGEYFCIYH TYPDGTYTGR
110 120 130 140 150
IFLEVLESSV AEHGARFQIP LLGAMAATLV VICTAVIVVV ALTRKKKALR
160
IHSVEGDLRR KSA
Length:163
Mass (Da):17,616
Last modified:November 3, 2009 - v1
Checksum:iC6583E4DFD609A67
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei163Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093010 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000484319; ENSP00000419706; ENSG00000181847
UCSCiuc062mqp.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JZW6_HUMAN
AccessioniPrimary (citable) accession number: C9JZW6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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