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C9JZU8

- C9JZU8_HUMAN

UniProt

C9JZU8 - C9JZU8_HUMAN

Protein
Submitted name:

Protein kinase C delta type

Gene

PRKCD

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. protein kinase C activity Source: Ensembl

    GO - Biological processi

    1. B cell proliferation Source: Ensembl
    2. defense response to bacterium Source: Ensembl
    3. immunoglobulin mediated immune response Source: Ensembl
    4. interleukin-10 production Source: Ensembl
    5. interleukin-12 production Source: Ensembl
    6. negative regulation of actin filament polymerization Source: Ensembl
    7. negative regulation of filopodium assembly Source: Ensembl
    8. negative regulation of insulin receptor signaling pathway Source: Ensembl
    9. negative regulation of peptidyl-tyrosine phosphorylation Source: Ensembl
    10. negative regulation of platelet aggregation Source: Ensembl
    11. positive regulation of apoptotic signaling pathway Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein kinase C delta typeImported
    Gene namesi
    Name:PRKCDImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:9399. PRKCD.

    Subcellular locationi

    GO - Cellular componenti

    1. cell-cell junction Source: Ensembl
    2. cytoplasm Source: Ensembl
    3. nuclear matrix Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiC9JZU8.
    BgeeiC9JZU8.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliC9JZU8.
    SMRiC9JZU8. Positions 1-77.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di2.60.40.150. 1 hit.
    InterProiIPR000008. C2_dom.
    [Graphical view]
    SUPFAMiSSF49562. SSF49562. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    C9JZU8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPFLRIAFN SYELGSLQAE DEANQPFCAV KMKEALSTER GKTLVQKKPT   50
    MYPEWKSTFD AHIYEGRVIQ IVLMRAA 77
    Length:77
    Mass (Da):8,796
    Last modified:November 3, 2009 - v1
    Checksum:i5D66D54545233D3E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei77 – 771Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC097015 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000478843; ENSP00000419726; ENSG00000163932.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC097015 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9JZU8.
    SMRi C9JZU8. Positions 1-77.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi C9JZU8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000478843 ; ENSP00000419726 ; ENSG00000163932 .

    Organism-specific databases

    HGNCi HGNC:9399. PRKCD.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi PRKCD. human.
    NextBioi 35488490.

    Gene expression databases

    ArrayExpressi C9JZU8.
    Bgeei C9JZU8.

    Family and domain databases

    Gene3Di 2.60.40.150. 1 hit.
    InterProi IPR000008. C2_dom.
    [Graphical view ]
    SUPFAMi SSF49562. SSF49562. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
      , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
      Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
      Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9JZU8_HUMAN
    AccessioniPrimary (citable) accession number: C9JZU8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3