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C9JXS9

- C9JXS9_HUMAN

UniProt

C9JXS9 - C9JXS9_HUMAN

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Protein
Submitted name:

Intersectin-1

Gene

ITSN1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. kinase activator activity Source: Ensembl

GO - Biological processi

  1. negative regulation of neuron apoptotic process Source: Ensembl
  2. positive regulation of protein kinase B signaling Source: Ensembl
  3. small GTPase mediated signal transduction Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intersectin-1Imported
Gene namesi
Name:ITSN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 21

Organism-specific databases

HGNCiHGNC:6183. ITSN1.

Subcellular locationi

GO - Cellular componenti

  1. endocytic vesicle Source: Ensembl
  2. lamellipodium Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiC9JXS9.
ExpressionAtlasiC9JXS9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JXS9.
SMRiC9JXS9. Positions 1-78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118985.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
[Graphical view]
SMARTiSM00027. EH. 1 hit.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
PS50031. EH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C9JXS9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ
60 70
SGLPQPVLAQ IWALADMNND GRMDQVEF
Length:78
Mass (Da):8,812
Last modified:November 3, 2009 - v1
Checksum:i25517C39A0DE9508
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei78 – 781Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP000308 Genomic DNA. No translation available.
AP000309 Genomic DNA. No translation available.
AP000310 Genomic DNA. No translation available.
AP000311 Genomic DNA. No translation available.
AP000312 Genomic DNA. No translation available.
AP000313 Genomic DNA. No translation available.
KF457227 Genomic DNA. No translation available.
KF511399 Genomic DNA. No translation available.
KF511404 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000451686; ENSP00000407132; ENSG00000205726.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP000308 Genomic DNA. No translation available.
AP000309 Genomic DNA. No translation available.
AP000310 Genomic DNA. No translation available.
AP000311 Genomic DNA. No translation available.
AP000312 Genomic DNA. No translation available.
AP000313 Genomic DNA. No translation available.
KF457227 Genomic DNA. No translation available.
KF511399 Genomic DNA. No translation available.
KF511404 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali C9JXS9.
SMRi C9JXS9. Positions 1-78.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000451686 ; ENSP00000407132 ; ENSG00000205726 .

Organism-specific databases

HGNCi HGNC:6183. ITSN1.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118985.

Miscellaneous databases

NextBioi 35488228.

Gene expression databases

Bgeei C9JXS9.
ExpressionAtlasi C9JXS9. baseline and differential.

Family and domain databases

Gene3Di 1.10.238.10. 1 hit.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
[Graphical view ]
SMARTi SM00027. EH. 1 hit.
[Graphical view ]
PROSITEi PS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
PS50031. EH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 21."
    Chromosome 21 mapping and sequencing consortium
    Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
    , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
    Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JXS9_HUMAN
AccessioniPrimary (citable) accession number: C9JXS9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3