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C9JXS9

- C9JXS9_HUMAN

UniProt

C9JXS9 - C9JXS9_HUMAN

Protein
Submitted name:

Intersectin-1

Gene

ITSN1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. kinase activator activity Source: Ensembl

    GO - Biological processi

    1. negative regulation of neuron apoptotic process Source: Ensembl
    2. positive regulation of protein kinase B signaling Source: Ensembl
    3. small GTPase mediated signal transduction Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Intersectin-1Imported
    Gene namesi
    Name:ITSN1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 21

    Organism-specific databases

    HGNCiHGNC:6183. ITSN1.

    Subcellular locationi

    GO - Cellular componenti

    1. endocytic vesicle Source: Ensembl
    2. lamellipodium Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiC9JXS9.
    BgeeiC9JXS9.

    Structurei

    3D structure databases

    ProteinModelPortaliC9JXS9.
    SMRiC9JXS9. Positions 1-78.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di1.10.238.10. 1 hit.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    [Graphical view]
    SMARTiSM00027. EH. 1 hit.
    [Graphical view]
    PROSITEiPS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 1 hit.
    PS50031. EH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    C9JXS9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ   50
    SGLPQPVLAQ IWALADMNND GRMDQVEF 78
    Length:78
    Mass (Da):8,812
    Last modified:November 3, 2009 - v1
    Checksum:i25517C39A0DE9508
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei78 – 781Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP000308 Genomic DNA. No translation available.
    AP000309 Genomic DNA. No translation available.
    AP000310 Genomic DNA. No translation available.
    AP000311 Genomic DNA. No translation available.
    AP000312 Genomic DNA. No translation available.
    AP000313 Genomic DNA. No translation available.
    KF457227 Genomic DNA. No translation available.
    KF511399 Genomic DNA. No translation available.
    KF511404 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000451686; ENSP00000407132; ENSG00000205726.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP000308 Genomic DNA. No translation available.
    AP000309 Genomic DNA. No translation available.
    AP000310 Genomic DNA. No translation available.
    AP000311 Genomic DNA. No translation available.
    AP000312 Genomic DNA. No translation available.
    AP000313 Genomic DNA. No translation available.
    KF457227 Genomic DNA. No translation available.
    KF511399 Genomic DNA. No translation available.
    KF511404 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9JXS9.
    SMRi C9JXS9. Positions 1-78.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000451686 ; ENSP00000407132 ; ENSG00000205726 .

    Organism-specific databases

    HGNCi HGNC:6183. ITSN1.
    GenAtlasi Search...

    Miscellaneous databases

    NextBioi 35488228.

    Gene expression databases

    ArrayExpressi C9JXS9.
    Bgeei C9JXS9.

    Family and domain databases

    Gene3Di 1.10.238.10. 1 hit.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    [Graphical view ]
    SMARTi SM00027. EH. 1 hit.
    [Graphical view ]
    PROSITEi PS00018. EF_HAND_1. 1 hit.
    PS50222. EF_HAND_2. 1 hit.
    PS50031. EH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 21."
      Chromosome 21 mapping and sequencing consortium
      Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
      , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
      Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9JXS9_HUMAN
    AccessioniPrimary (citable) accession number: C9JXS9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3