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Protein
Submitted name:

Synaptotagmin-1

Gene

SYT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Synaptotagmin-1Imported
Gene namesi
Name:SYT1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:11509. SYT1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei59 – 8022HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiC9JX50.
PeptideAtlasiC9JX50.

Expressioni

Gene expression databases

BgeeiENSG00000067715.
ExpressionAtlasiC9JX50. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000261205.

Structurei

3D structure databases

ProteinModelPortaliC9JX50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IT3Q. Eukaryota.
ENOG410Z15P. LUCA.
GeneTreeiENSGT00760000118973.
HOGENOMiHOG000232127.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
InterProiIPR000008. C2_dom.
IPR001565. Synaptotagmin.
IPR015428. Synaptotagmin1.
[Graphical view]
PANTHERiPTHR10024:SF239. PTHR10024:SF239. 1 hit.
PRINTSiPR00399. SYNAPTOTAGMN.
SUPFAMiSSF49562. SSF49562. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JX50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSESHHEAL AAPPVTTVAT VLPSNATEPA SPGEGKEDAF SKLKEKFMNE
60 70 80 90 100
LHKIPLPPWA LIAIAIVAVL LVLTCCFCIC KKCLFKKKNK KKGKEKGGKN
110 120 130 140 150
AINMKDVKDL GKTMKDQALK DDDAETGLTD GEEKEEPKEE EKLGKLQYSL
160 170 180
DYDFQNNQLL VGIIQAAELP ALDMGGTSDP YV
Length:182
Mass (Da):19,873
Last modified:February 17, 2016 - v7
Checksum:iFC7A34EFD0065F02
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei182 – 1821Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027288 Genomic DNA. No translation available.
AC073570 Genomic DNA. No translation available.
AC073572 Genomic DNA. No translation available.
AC073606 Genomic DNA. No translation available.
AC073616 Genomic DNA. No translation available.
AC078917 Genomic DNA. No translation available.
AC090709 Genomic DNA. No translation available.
KF455679 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000446242; ENSP00000401559; ENSG00000067715.
UCSCiuc058rgr.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC027288 Genomic DNA. No translation available.
AC073570 Genomic DNA. No translation available.
AC073572 Genomic DNA. No translation available.
AC073606 Genomic DNA. No translation available.
AC073616 Genomic DNA. No translation available.
AC078917 Genomic DNA. No translation available.
AC090709 Genomic DNA. No translation available.
KF455679 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9JX50.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000261205.

Proteomic databases

PaxDbiC9JX50.
PeptideAtlasiC9JX50.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000446242; ENSP00000401559; ENSG00000067715.
UCSCiuc058rgr.1. human.

Organism-specific databases

HGNCiHGNC:11509. SYT1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IT3Q. Eukaryota.
ENOG410Z15P. LUCA.
GeneTreeiENSGT00760000118973.
HOGENOMiHOG000232127.

Miscellaneous databases

ChiTaRSiSYT1. human.

Gene expression databases

BgeeiENSG00000067715.
ExpressionAtlasiC9JX50. baseline and differential.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
InterProiIPR000008. C2_dom.
IPR001565. Synaptotagmin.
IPR015428. Synaptotagmin1.
[Graphical view]
PANTHERiPTHR10024:SF239. PTHR10024:SF239. 1 hit.
PRINTSiPR00399. SYNAPTOTAGMN.
SUPFAMiSSF49562. SSF49562. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC9JX50_HUMAN
AccessioniPrimary (citable) accession number: C9JX50
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: February 17, 2016
Last modified: September 7, 2016
This is version 56 of the entry and version 7 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.