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Protein
Submitted name:

Alpha-2-HS-glycoprotein

Gene

AHSG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-2-HS-glycoproteinImported
Gene namesi
Name:AHSGImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:349. AHSG.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000145192.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500299787219 – 368Sequence analysisAdd BLAST350

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi89 ↔ 100PROSITE-ProRule annotation
Disulfide bondi147 ↔ 150PROSITE-ProRule annotation
Disulfide bondi209 ↔ 220PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

MaxQBiC9JV77.
PaxDbiC9JV77.
PeptideAtlasiC9JV77.
PRIDEiC9JV77.

Expressioni

Gene expression databases

BgeeiENSG00000145192.
ExpressionAtlasiC9JV77. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JV77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 133Cystatin fetuin-A-typeInterPro annotationAdd BLAST107
Domaini145 – 256Cystatin fetuin-A-typeInterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the fetuin family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IK8F. Eukaryota.
ENOG4111RIP. LUCA.
GeneTreeiENSGT00530000063413.
HOGENOMiHOG000290189.
OMAiETTCHVL.
OrthoDBiEOG091G0FHG.

Family and domain databases

CDDicd00042. CY. 2 hits.
InterProiView protein in InterPro
IPR000010. Cystatin_dom.
IPR025760. Cystatin_Fetuin_A.
IPR001363. Prot_inh_fetuin_CS.
PfamiView protein in Pfam
PF00031. Cystatin. 1 hit.
SMARTiView protein in SMART
SM00043. CY. 2 hits.
PROSITEiView protein in PROSITE
PS51529. CYSTATIN_FETUIN_A. 2 hits.
PS01255. FETUIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C9JV77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSLVLLLCL AQLWGCHSAP HGPGLIYRQP NCDDPETEEA ALVAIDYINQ
60 70 80 90 100
NLPWGYKHTL NQIDEVKVWP QQPSGELFEI EIDTLETTCH VLDPTPVARC
110 120 130 140 150
SVRQLKEHAV EGDCDFQLLK LDGKFSVVYA KCDSSPADSA EDVRKVCQDC
160 170 180 190 200
PLLAPLNDTR VVHAAKAALA AFNAQNNGSN FQLEEISRAQ LVPLPPSTYV
210 220 230 240 250
EFTVSGTDCV AKEATEAAKC NLLAEKQYGF CKATLSEKLG GAEVAVTCMV
260 270 280 290 300
FQTQPVSSQP QPEGANEAVP TPVVDPDAPP SPPLGAPGLP PAGSPPDSHV
310 320 330 340 350
LLAAPPGHQL HRAHYDLRHT FMGVVSLGSP SGEVSHPRKT RTVVQPSVGA
360
AAGPVVPPCP GRIRHFKV
Length:368
Mass (Da):39,412
Last modified:November 3, 2009 - v1
Checksum:iCDA313F3C7DEB940
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC068631 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000273784; ENSP00000273784; ENSG00000145192.
UCSCiuc062rbw.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiC9JV77_HUMAN
AccessioniPrimary (citable) accession number: C9JV77
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: July 5, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported