Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CASP8 and FADD-like apoptosis regulator

Gene

CFLAR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CASP8 and FADD-like apoptosis regulatorImported
Gene namesi
Name:CFLARImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:1876. CFLAR.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000003402.

PTM / Processingi

Proteomic databases

MaxQBiC9JV51.
PaxDbiC9JV51.
PeptideAtlasiC9JV51.
PRIDEiC9JV51.

Expressioni

Gene expression databases

BgeeiENSG00000003402.
ExpressionAtlasiC9JV51. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JV51.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 73DED (death effector)InterPro annotationAdd BLAST73
Domaini92 – 118DED (death effector)InterPro annotationAdd BLAST27

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
GeneTreeiENSGT00530000064199.
HOGENOMiHOG000069972.

Family and domain databases

InterProiView protein in InterPro
IPR011029. DEATH-like_dom.
IPR001875. DED_dom.
PfamiView protein in Pfam
PF01335. DED. 1 hit.
SMARTiView protein in SMART
SM00031. DED. 1 hit.
SUPFAMiSSF47986. SSF47986. 2 hits.
PROSITEiView protein in PROSITE
PS50168. DED. 2 hits.

Sequencei

Sequence statusi: Fragment.

C9JV51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL
60 70 80 90 100
SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI
110
GEDLDKSDVS SLIFLMKD
Length:118
Mass (Da):13,689
Last modified:November 3, 2009 - v1
Checksum:i7235F3EEBB51963F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei118Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007283 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000417748; ENSP00000412882; ENSG00000003402.
UCSCiuc061rie.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiC9JV51_HUMAN
AccessioniPrimary (citable) accession number: C9JV51
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: July 5, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported