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Protein

Putative adrenomedullin-5-like protein

Gene

ADM5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Probable non-functional remnant of adrenomedullin-5.1 Publication

Enzyme and pathway databases

BioCyciZFISH:G66-33843-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative adrenomedullin-5-like protein
Gene namesi
Name:ADM5
Synonyms:C19orf76
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:27293. ADM5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000224420.
PharmGKBiPA165393101.

Polymorphism and mutation databases

BioMutaiADM5.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000039255119 – 153Putative adrenomedullin-5-like proteinAdd BLAST135

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi39 ↔ 44By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiC9JUS6.
PRIDEiC9JUS6.

Expressioni

Gene expression databases

BgeeiENSG00000224420.
GenevisibleiC9JUS6. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000393631.

Structurei

3D structure databases

ProteinModelPortaliC9JUS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adrenomedullin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JMZP. Eukaryota.
ENOG41116Z5. LUCA.
GeneTreeiENSGT00730000112484.
HOGENOMiHOG000170821.
InParanoidiC9JUS6.
OMAiAQCPARW.
OrthoDBiEOG091G1284.
PhylomeDBiC9JUS6.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C9JUS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIHILILLL LLAFSAQGDL DTAARRGQHQ VPQHRGHVCY LGVCRTHRLA
60 70 80 90 100
EIIYWIRCLH QGALGEGQPR APGPLQLWAP PVARGGSPAR FPGFRPAARG
110 120 130 140 150
LAQCPARWVT SGTARPLLGF SLPICMLELL LHISSPLTPA PETVFPSPSP

GCD
Length:153
Mass (Da):16,532
Last modified:November 3, 2009 - v1
Checksum:i2AC1CFBEB867B30D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011495 Genomic DNA. No translation available.
CH471177 Genomic DNA. Translation: EAW52522.1.
BC032764 mRNA. No translation available.
CCDSiCCDS46146.1.
RefSeqiNP_001094810.1. NM_001101340.1.
UniGeneiHs.311193.
Hs.607562.

Genome annotation databases

EnsembliENST00000420022; ENSP00000393631; ENSG00000224420.
GeneIDi199800.
KEGGihsa:199800.
UCSCiuc002pph.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011495 Genomic DNA. No translation available.
CH471177 Genomic DNA. Translation: EAW52522.1.
BC032764 mRNA. No translation available.
CCDSiCCDS46146.1.
RefSeqiNP_001094810.1. NM_001101340.1.
UniGeneiHs.311193.
Hs.607562.

3D structure databases

ProteinModelPortaliC9JUS6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000393631.

Polymorphism and mutation databases

BioMutaiADM5.

Proteomic databases

PaxDbiC9JUS6.
PRIDEiC9JUS6.

Protocols and materials databases

DNASUi199800.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000420022; ENSP00000393631; ENSG00000224420.
GeneIDi199800.
KEGGihsa:199800.
UCSCiuc002pph.3. human.

Organism-specific databases

CTDi199800.
GeneCardsiADM5.
HGNCiHGNC:27293. ADM5.
neXtProtiNX_C9JUS6.
OpenTargetsiENSG00000224420.
PharmGKBiPA165393101.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JMZP. Eukaryota.
ENOG41116Z5. LUCA.
GeneTreeiENSGT00730000112484.
HOGENOMiHOG000170821.
InParanoidiC9JUS6.
OMAiAQCPARW.
OrthoDBiEOG091G1284.
PhylomeDBiC9JUS6.

Enzyme and pathway databases

BioCyciZFISH:G66-33843-MONOMER.

Miscellaneous databases

GenomeRNAii199800.
PROiC9JUS6.

Gene expression databases

BgeeiENSG00000224420.
GenevisibleiC9JUS6. HS.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiADM5_HUMAN
AccessioniPrimary (citable) accession number: C9JUS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: November 3, 2009
Last modified: November 2, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.