ID   C9JU58_HUMAN            Unreviewed;       156 AA.
AC   C9JU58;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=VPS41 subunit of HOPS complex {ECO:0000313|Ensembl:ENSP00000412974.1};
DE   Flags: Fragment;
GN   Name=VPS41 {ECO:0000313|Ensembl:ENSP00000412974.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000412974.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000412974.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000412974.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC004850; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC005247; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC011292; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; C9JU58; -.
DR   SMR; C9JU58; -.
DR   MassIVE; C9JU58; -.
DR   MaxQB; C9JU58; -.
DR   PeptideAtlas; C9JU58; -.
DR   ProteomicsDB; 11689; -.
DR   Antibodypedia; 13056; 158 antibodies from 31 providers.
DR   Ensembl; ENST00000413141.5; ENSP00000412974.1; ENSG00000006715.16.
DR   UCSC; uc064cyw.1; human.
DR   HGNC; HGNC:12713; VPS41.
DR   VEuPathDB; HostDB:ENSG00000006715; -.
DR   GeneTree; ENSGT00390000000481; -.
DR   HOGENOM; CLU_1690780_0_0_1; -.
DR   ChiTaRS; VPS41; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000006715; Expressed in calcaneal tendon and 185 other cell types or tissues.
DR   ExpressionAtlas; C9JU58; baseline and differential.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR045111; Vps41/Vps8.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR12616; VACUOLAR PROTEIN SORTING VPS41; 1.
DR   PANTHER; PTHR12616:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:C9JU58,
KW   ECO:0007829|MaxQB:C9JU58};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   NON_TER         156
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000412974.1"
SQ   SEQUENCE   156 AA;  17875 MW;  1998158CE9E4AE23 CRC64;
     MPKKLQSESP VKINQISLDE SGEHMGVCSE DGKVQVFGLY SGEEFHETFD CPIKIIAVHP
     HFVRSSCKQF VTGGKKLLLF ERSWMNRWKS AVLHEGEGNI RSVKWRGHLI AWANNMGVKI
     FDIISKQRIT NVPRDDISLR PDMYPCSLCW KDNVTL
//