C9JTQ0 (ANR63_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ankyrin repeat domain-containing protein 63

Gene names

Name:

ANKRD63

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 5 ANK repeats.

Ontologies

Keywords
Domain	ANK repeat Repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 380	380	Ankyrin repeat domain-containing protein 63		PRO_0000411002
Regions
	Repeat	11 – 40	30	ANK 1
	Repeat	46 – 79	34	ANK 2
	Repeat	83 – 112	30	ANK 3
	Repeat	116 – 145	30	ANK 4
	Repeat	153 – 182	30	ANK 5

Sequences

	Sequence		Length	Mass (Da)
	C9JTQ0 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 68DE84AAC8CD0106	FASTA	380	39,620
	10 20 30 40 50 60 MLKPKDLCPR AGTRTFLEAM QAGKVHLARF VLDALDRSII DCRAEQGRTP LMVAVGLPDP 70 80 90 100 110 120 ALRARFVRLL LEQGAAVNLR DERGRTALSL ACERGHLDAV QLLVQFSGDP EAADSAGNSP 130 140 150 160 170 180 VMWAAACGHG AVLEFLVRSF RRLGLRLDRT NRAGLTALQL AAARGHGTCV QALTGPWGRA 190 200 210 220 230 240 AAAAAARGSN SDSPPGRPAP AASPEHRRPS PRRLPRPLLA RFARAAGGHG GEAGSAGKNS 250 260 270 280 290 300 GRHRAQGSER PELGRSMSLA LGAVTEEEAA RLRAGALMAL PNSPQSSGTG RWRSQEVLEG 310 320 330 340 350 360 APPTLAQAPI GLSPHPEGGP GSGRLGLRRR STAPDIPSLV GEAPGPESGP ELEANALSVS 370 380 VPGPNPWQAG TEAVVLRAQR

References

[1]

"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC020658 Genomic DNA. No translation available.
IPI	IPI00888968.
RefSeq	NP_001177408.1. NM_001190479.1.
UniGene	Hs.711376.
3D structure databases
ProteinModelPortal	C9JTQ0.
SMR	C9JTQ0. Positions 14-173.
ModBase	Search...
Proteomic databases
PaxDb	C9JTQ0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000434396; ENSP00000399547; ENSG00000230778.
GeneID	100131244.
KEGG	hsa:100131244.
UCSC	uc021sjf.1. human.
Organism-specific databases
CTD	100131244.
GeneCards	GC15M040574.
HGNC	HGNC:40027. ANKRD63.
neXtProt	NX_C9JTQ0.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0666.
HOGENOM	HOG000231848.
OMA	HGAVLEF.
OrthoDB	EOG4NGGN5.
Gene expression databases
Bgee	C9JTQ0.
Family and domain databases
Gene3D	1.25.40.20. 1 hit.
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. [Graphical view]
Pfam	PF12796. Ank_2. 1 hit. [Graphical view]
SMART	SM00248. ANK. 3 hits. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 2 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	100131244.
NextBio	20773248.

Entry information

Entry name

ANR63_HUMAN

Accession

Primary (citable) accession number: C9JTQ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 27, 2011
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.