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Protein
Submitted name:

cAMP-dependent protein kinase type I-beta regulatory subunit

Gene

PRKAR1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei202cAMP 1UniRule annotation1
Binding sitei211cAMP 1UniRule annotation1

GO - Molecular functioni

Keywordsi

LigandcAMP, cAMP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP-dependent protein kinase type I-beta regulatory subunitImported
Gene namesi
Name:PRKAR1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000188191.14.
HGNCiHGNC:9390. PRKAR1B.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188191.

PTM / Processingi

Proteomic databases

MaxQBiC9JSK5.
PeptideAtlasiC9JSK5.
PRIDEiC9JSK5.

Expressioni

Gene expression databases

BgeeiENSG00000188191.
ExpressionAtlasiC9JSK5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JSK5.
SMRiC9JSK5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini137 – 252Cyclic nucleotide-bindingInterPro annotationAdd BLAST116
Domaini255 – 297Cyclic nucleotide-bindingInterPro annotationAdd BLAST43

Phylogenomic databases

eggNOGiKOG1113. Eukaryota.
COG0664. LUCA.
GeneTreeiENSGT00530000062947.
HOGENOMiHOG000196669.

Family and domain databases

CDDicd00038. CAP_ED. 2 hits.
Gene3Di1.20.890.10. 1 hit.
2.60.120.10. 2 hits.
InterProiView protein in InterPro
IPR012198. cAMP_dep_PK_reg_su.
IPR003117. cAMP_dep_PK_reg_su_I/II_a/b.
IPR036536. cAMP_dep_PK_reg_su_sf.
IPR018490. cNMP-bd-like.
IPR018488. cNMP-bd_CS.
IPR000595. cNMP-bd_dom.
IPR014710. RmlC-like_jellyroll.
PfamiView protein in Pfam
PF00027. cNMP_binding. 1 hit.
PF02197. RIIa. 1 hit.
PIRSFiPIRSF000548. PK_regulatory. 1 hit.
SMARTiView protein in SMART
SM00100. cNMP. 1 hit.
SM00394. RIIa. 1 hit.
SUPFAMiSSF47391. SSF47391. 1 hit.
SSF51206. SSF51206. 2 hits.
PROSITEiView protein in PROSITE
PS00888. CNMP_BINDING_1. 1 hit.
PS00889. CNMP_BINDING_2. 1 hit.
PS50042. CNMP_BINDING_3. 2 hits.

Sequencei

Sequence statusi: Fragment.

C9JSK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASPPACPSE EDESLKGCEL YVQLHGIQQV LKDCIVHLCI SKPERPMKFL
60 70 80 90 100
REHFEKLEKE ENRQILARQK SNSQSDSHDE EVSPTPPNPV VKARRRRGGV
110 120 130 140 150
SAEVYTEEDA VSYVRKVIPK DYKTMTALAK AISKNVLFAH LDDNERSDIF
160 170 180 190 200
DAMFPVTHIA GETVIQQGNE GDNFYVVDQG EVDVYVNGEW VTNISEGGSF
210 220 230 240 250
GELALIYGTP RAATVKAKTD LKLWGIDRDS YRRILMGSTL RKRKMYEEFL
260 270 280 290
SKVSILESLE KWERLTVADA LEPVQFEDGE KIVVQGEPGD DFYIITE
Length:297
Mass (Da):33,632
Last modified:November 3, 2009 - v1
Checksum:i39B000C2D9D417E6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei297Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC144411 Genomic DNA. No translation available.
AC147651 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000430040; ENSP00000402648; ENSG00000188191.
UCSCiuc064asz.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9JSK5_HUMAN
AccessioniPrimary (citable) accession number: C9JSK5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: January 31, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported