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Protein
Submitted name:

cAMP-dependent protein kinase type I-beta regulatory subunit

Gene

PRKAR1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei202cAMP 1UniRule annotation1
Binding sitei211cAMP 1UniRule annotation1

GO - Molecular functioni

Keywordsi

LigandcAMP, cAMP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP-dependent protein kinase type I-beta regulatory subunitImported
Gene namesi
Name:PRKAR1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000188191.14
HGNCiHGNC:9390 PRKAR1B

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188191

PTM / Processingi

Proteomic databases

MaxQBiC9JSK5
PeptideAtlasiC9JSK5
PRIDEiC9JSK5

Expressioni

Gene expression databases

BgeeiENSG00000188191
ExpressionAtlasiC9JSK5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JSK5
SMRiC9JSK5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini137 – 252Cyclic nucleotide-bindingInterPro annotationAdd BLAST116
Domaini255 – 297Cyclic nucleotide-bindingInterPro annotationAdd BLAST43

Phylogenomic databases

eggNOGiKOG1113 Eukaryota
COG0664 LUCA
GeneTreeiENSGT00530000062947
HOGENOMiHOG000196669

Family and domain databases

CDDicd00038 CAP_ED, 2 hits
Gene3Di2.60.120.10, 2 hits
InterProiView protein in InterPro
IPR012198 cAMP_dep_PK_reg_su
IPR003117 cAMP_dep_PK_reg_su_I/II_a/b
IPR018490 cNMP-bd-like
IPR018488 cNMP-bd_CS
IPR000595 cNMP-bd_dom
IPR014710 RmlC-like_jellyroll
PfamiView protein in Pfam
PF00027 cNMP_binding, 1 hit
PF02197 RIIa, 1 hit
PIRSFiPIRSF000548 PK_regulatory, 1 hit
SMARTiView protein in SMART
SM00100 cNMP, 1 hit
SM00394 RIIa, 1 hit
SUPFAMiSSF51206 SSF51206, 2 hits
PROSITEiView protein in PROSITE
PS00888 CNMP_BINDING_1, 1 hit
PS00889 CNMP_BINDING_2, 1 hit
PS50042 CNMP_BINDING_3, 2 hits

Sequencei

Sequence statusi: Fragment.

C9JSK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASPPACPSE EDESLKGCEL YVQLHGIQQV LKDCIVHLCI SKPERPMKFL
60 70 80 90 100
REHFEKLEKE ENRQILARQK SNSQSDSHDE EVSPTPPNPV VKARRRRGGV
110 120 130 140 150
SAEVYTEEDA VSYVRKVIPK DYKTMTALAK AISKNVLFAH LDDNERSDIF
160 170 180 190 200
DAMFPVTHIA GETVIQQGNE GDNFYVVDQG EVDVYVNGEW VTNISEGGSF
210 220 230 240 250
GELALIYGTP RAATVKAKTD LKLWGIDRDS YRRILMGSTL RKRKMYEEFL
260 270 280 290
SKVSILESLE KWERLTVADA LEPVQFEDGE KIVVQGEPGD DFYIITE
Length:297
Mass (Da):33,632
Last modified:November 3, 2009 - v1
Checksum:i39B000C2D9D417E6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei297Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC144411 Genomic DNA No translation available.
AC147651 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000430040; ENSP00000402648; ENSG00000188191
UCSCiuc064asz.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JSK5_HUMAN
AccessioniPrimary (citable) accession number: C9JSK5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: April 25, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health