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Protein
Submitted name:

Tissue factor pathway inhibitor

Gene

TFPI

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Tissue factor pathway inhibitorImported
Gene namesi
Name:TFPIImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000003436.14.
HGNCiHGNC:11760. TFPI.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000003436.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501408688729 – 106Sequence analysisAdd BLAST78

Expressioni

Gene expression databases

BgeeiENSG00000003436.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 104BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4295. Eukaryota.
ENOG410XQNP. LUCA.
GeneTreeiENSGT00740000114929.
HOGENOMiHOG000231818.

Family and domain databases

CDDicd00109. KU. 1 hit.
Gene3Di4.10.410.10. 1 hit.
InterProiView protein in InterPro
IPR002223. Kunitz_BPTI.
IPR036880. Kunitz_BPTI_sf.
IPR020901. Prtase_inh_Kunz-CS.
IPR029864. TFPI1.
PANTHERiPTHR10083:SF317. PTHR10083:SF317. 1 hit.
PfamiView protein in Pfam
PF00014. Kunitz_BPTI. 1 hit.
PRINTSiPR00759. BASICPTASE.
SMARTiView protein in SMART
SM00131. KU. 1 hit.
SUPFAMiSSF57362. SSF57362. 1 hit.
PROSITEiView protein in PROSITE
PS00280. BPTI_KUNITZ_1. 1 hit.
PS50279. BPTI_KUNITZ_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JQ14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYTMKKVHA LWASVCLLLN LAPAPLNADS EEDEEHTIIT DTELPPLKLM
60 70 80 90 100
HSFCAFKADD GPCKAIMKRF FFNIFTRQCE EFIYGGCEGN QNRFESLEEC

KKMCTR
Length:106
Mass (Da):12,216
Last modified:November 3, 2009 - v1
Checksum:iC94ABD71E05B6455
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei106Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007319 Genomic DNA. No translation available.
AC098485 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000421427; ENSP00000408170; ENSG00000003436.
ENST00000437725; ENSP00000388159; ENSG00000003436.
UCSCiuc061qmw.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9JQ14_HUMAN
AccessioniPrimary (citable) accession number: C9JQ14
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported